Prognostic Value of the Disodium Phosphate 32P Uptake Test in Uveal Melanoma

Intravascular Presence of Tumor Cells as Prognostic Parameter in Uveal Melanoma: A 35-Year Survey

“…[23][24][25] However, there is only a limited number of studies in uveal melanoma concerning ingrowth of tumor cells in blood vessels. 17,18 In our center, 715 eyes were enu- Only the primarily enucleated eyes (n ϭ 643) were analyzed. We did not include eyes with prior treatment, such as ruthenium-106 brachytherapy, in our study, due to the fact that the tumor characteristics could have been modified by the prior therapy.…”

“…One study by our group mentioned this parameter, but this study was limited in number of specimens and time. 17 Coupland et al 18 recently studied extraocular extension in relation to vortex veins.…”

Angiogenesis in Uveal Melanoma

“…Several studies have shown that the presence of a high local vascular density in uveal melanomas is associated with worse survival, as is ingrowth of tumour cells into the lumen of tumour blood vessels and into the sclera [5,12,13] . This is a logical finding, as tumour cells Uveal melanoma is the most frequently occurring malignancy in the adult eye.…”