Terpenes from Inula verbascifolia

Ahmed, Ahmed A.; Mohamed, Abou El‐Hamd H.; Τζακου, Ολγα; Petropoulou, Alexandra; Hassan, Mohamed E.; El‐Maghraby, M. A.; Zeller, Klaus‐Peter

doi:10.1016/s0031-9422(02)00478-8

Cited by 11 publications

(25 citation statements)

References 5 publications

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“…A germacrene C-4 − C-5 epoxide would lead to a guaiane, whereas a germacrene C-1 − C-10 epoxide would lead to a eudesmane (Brown et al, 1975;Piet et al, 1995). The previously reported germacrene from I. verbascifolia was a germacrene C-4 − C-5 epoxide (Ahmed et al, 2003), thus agreeing well with the two new guaianolides reported here.…”

Section: Resultssupporting

confidence: 86%

“…Our previous work on I. verbascifolia afforded the isolation of two new xanthanes and a new germacrane (Ahmed et al, 2003), while in the present work two new guaianes were isolated, complementing the set of the previously reported compounds. Thus, the phytochemistry of I. verbascifolia is in agreement with that of the other species of the genus Inula.…”

Section: Resultssupporting

confidence: 81%

“…Plants of the genus Inula have been shown to contain high levels of sesquiterpene lactones and have recently received considerable attention due to their antineoplastic and anti-infl ammatory effects Harvala et al, 2002;Hua et al, 2012;Kang et al, 2004;Konishi et al, 2002;Li et al, 2012;Won et al, 2004;Chia and Hsin, 2007). In continuation of our investigation of the medicinal plants of the Asteraceae family (Ahmed et al, 2003), we investigated the chemical constituents of I. verbascifolia. (Willd.)…”

Section: Introductionmentioning

confidence: 99%

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New Guaianolide-Type Sesquiterpene Lactones from Inula verbascifolia

Mohamed

Mahmoud²,

Abdel-Latif³

et al. 2013

Zeitschrift Für Naturforschung C

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Section: Resultssupporting

confidence: 86%

Section: Resultssupporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

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New Guaianolide-Type Sesquiterpene Lactones from Inula verbascifolia

Mohamed

Mahmoud²,

Abdel-Latif³

et al. 2013

Zeitschrift Für Naturforschung C

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“…The investigation on Inula species has brought various significant bioactive components of this genus into view. These components are sesquiterpenes, lactones, flavonoids, glycosidases and phenolic compounds (Ulubelen et al, 1987;Vajs et al, 1989;Shao et al, 1996;Ahmed et al, 2003;Qi et al, 2008). It is difficult to obtain pure genomic DNA from these species, which are rich in secondary components.…”

Section: Introductionmentioning

confidence: 99%

Comparative Analysis of the Genomic DNA Isolation Methods on <i>Inula</i> sp. (Asteraceae)

et al. 2016

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Simple, fast, low-cost and high throughput protocols are required for DNA isolation of plant species. In this study, phenol chloroform isoamyl alcohol and commercial (Sigma) DNA isolation kit methods were applied on some Inula species that belong to Asteraceae family. Genomic DNA amounts, A260, A280, A260/A230 and purity degrees (A260/A280) that were obtained through both methods were measured through electrophoresis and spectrophotometer. Additionally, PCR amplification was realized by primer pairs specific to nrDNA ITS, cpDNA ndhF (972F-1603R) and trnL-F regions. Results showed that maximum genomic DNA in nanograms obtained by phenol chloroform isoamyl alcohol method. The study also revealed that I. macrocephala had the maximum DNA and I. heterolepis had the minimum DNA amount. A260/A280 purity degrees showed that the highest and lowest purity in gDNAs obtained through phenol-chloroform isoamyl alcohol method were in I.aucheriana and I. salicina, respectively. The highest and lowest purity degrees of gDNAs obtained through commercial kit was observed in I. fragilis and I. macrocephala samples, respectively. PCR amplification results showed that while band profiles of each three regions (ITS, trnL-F and ndhF) did not yield positive results in PCR amplifications using phenol-chloroform isoamyl alcohol method; PCR band profiles obtained through commercial kit yielded positive results. As a result, it is fair to say that the relation of genomic DNA with PCR was found to be more efficient although the maximum amount of genomic DNA was obtained through phenol chloroform isoamyl alcohol method.

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“…verbascifolia was included in the project ''Evaluation and introduction of autochthonous ornamental plants in floriculture'' for its characterization and valorization as, for instance, a garden plant. Moreover, some Greek subspecies of I. verbascifolia produce volatile compounds (Tzakou et al, 2001;Ahmed et al, 2003) as well as compounds with potential anti-tumour activity (Harvala et al, 2002). Other members of the genus are also known for their volatile compounds , and are very often used in herbal medicine (Blaschek et al, 1998), or have some components with positive effects on different diseases (Tripathi et al, 1988;Newall et al, 1996;Miller, 1998, etc.).…”

Section: Introductionmentioning

confidence: 99%