Synthesis, characterization and antimicrobial activities of transition metal complexes of N,N -dialkyl- N′ -(2-chlorobenzoyl)thiourea derivatives

Metal based drugs: design, synthesis and in-vitro antimicrobial screening of Co(II), Ni(II), Cu(II) and Zn(II) complexes with some new carboxamide derived compounds: crystal structures of N-[ethyl(propan-2-yl)carbamothioyl]thiophene-2-carboxamide and its copper(II) complex

“…The IR spectra of all the metal(II) complexes exhibited major changes in comparison to the spectra of the subsequent ligands. The most prominent change observed was, the carbonyl (C¼O) and thiocarbonyl (C¼S) bands originally appearing at 1675-1680 and 1235-1250 cm À1 in the spectra of the ligand, shifted to lower frequency by 13-15 cm À1 at 1660-1670 and 1220-1237 cm À1 , respectively, in the spectra of metal(II) complexes indicating 1,26 the involvement in coordination with the metal(II) ions. The decrease in frequency is due to delocalization of electrons …”

“…The spectra of all the ligands (L 1 -L 3 ) showed a broad singlet peak at 11.53-11.62 ppm due to N-H proton 1,28 and the protons of ethyl and isopropyl groups (C 8 -H, C 9 -H, C 10 -H, C 11 -H and C 12 -H) were observed as doublet to multiplet at 0.93-2.60 ppm. The methyl (CH 3 ) protons of (L 2 ) and C 3 -H to C 5 -H protons of all ligands were observed at 2.45 and 7.10-8.19 ppm as a singlet and doublet, respectively.…”

“…Many biologically active thiourea-based (carboxamide) compounds have been reported possessing antibacterial [1][2][3] , antifungal 4,5 , anticancer 6,7 , antiviral 8 , pesticidal 9 , cytotoxic 10 , herbicidal 11 and insecticidal 12 activities. Thiourea derivatives have been effectively used in organocatalysis 13 and as curing agents for epoxy resins.…”

Deposition and characterization of Cu$_{9}$S$_{5}$ nanocrystals from unsymmetrical [(Hex)(Me)NC(S)NC(O)C$_{6}$H$_{3}$(NO$_{2})_{2}$-3,5]$_{2}$Cu(II) and [(Et)(Bu)NC(S)NC(O)C$_{6}$H$_{4}$-4-NO$_{2}$]$_{2}$Cu(II) complexes by colloidal thermolysis method

“…Arslan and co-workers 19,20 reported the complexation of copper(II) and zinc(II) with acylthiourea ligands and concluded that the coordination was through multifunction S,O-donor atoms, using infrared spectroscopy and X-ray diffractions studies. Binzet and co-workers 21 reported that the complexes of methylthiourea have coordination through sulfur donor atoms.…”

Aerosol-assisted chemical vapor deposition of copper sulfide nanostructured thin film from newly synthesized single-source precursor

“…Besides focusing on the applications of these ligands, special attention has been placed on their coordination Arslan et al 20 and Benzet et al 21 reported the complexation of Cu(II) and Zn(II) with thiourea derivatives and concluded that the coordination was through the sulfur and oxygen atom, using infrared spectroscopy and X-ray diffractions to determine the coordination. In addition, complexes prepared using the alkyl thiourea, such as methylthiourea, showed, using infrared spectroscopy, that the coordination also was through sulfur.…”