Surveilan Pneumokokus dan Dampak Pneumonia pada Anak Balita

Purniti, Putu Siadi; Subanada, Ida Bagus; Kari, Ilkka; Arhana, Bnp; Iswari, Ida Sri; Tarini, Ni Made Adi

doi:10.14238/sp12.5.2011.359-64

Cited by 3 publications

(3 citation statements)

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“…So far, studies in Indonesia failed to reveal the burden of pneumococcal diseases in Indonesia probably due to technical problems [20] , [21] , thus, limiting the availability of data needed to develop appropriate policies and strategies to control pneumococcal disease, which is considered as one of the most important infectious diseases, in particular for toddlers and elderly worldwide. This underscores the need for surveillance of pneumococcal disease in Indonesia using locally implementable laboratory methods.…”

Section: Discussionmentioning

confidence: 99%

Nasopharyngeal Carriage of Streptococcus pneumonia in Pneumonia-Prone Age Groups in Semarang, Java Island, Indonesia

et al. 2014

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Introduction Streptococcus pneumoniae is a worldwide occurring pathogen Nasopharyngeal carriage of Streptococcus pneumoniae precedes pneumonia and other pneumococcal diseases in the community. Little is known about S. pneumoniae carriage in Indonesia, complicating strategies to control pneumococcal diseases. We investigated nasopharyngeal carriage of S. pneumoniae in Semarang, Indonesia.MethodsA population-based survey was performed in Semarang, Indonesia. Nasopharyngeal swabs and questionnaires were taken from 496 healthy young (6–60 month-old) children and 45–70 year-old adults.ResultsForty-three percent of children aged 6–60 months and 11% of adults aged 45–75 years carried S. pneumoniae. Determinants of carriage were being a child (OR 7.7; 95% CI = 4.5–13.0), passive smoking (OR 2.1; 95% CI = 1.3–3.4), and contact with toddler(s) at home (OR 3.0; 95% CI = 1.9–4.7). The most frequent serotypes found were 6A/B and 15B/C. The current commercially available vaccines cover <50% serotypes found in children. Twenty-four percent of S. pneumoniae strains were penicillin non-susceptible, and 45% were resistant to cotrimoxazol.ConclusionsThe limited coverage of commercially available vaccines against the serotypes found in this population, and the high proportion of non-susceptibility to penicillin and cotrimoxazol suggest the need for region-specific information and strategies to control S. pneumoniae.

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Section: Discussionmentioning

confidence: 99%

Nasopharyngeal Carriage of Streptococcus pneumonia in Pneumonia-Prone Age Groups in Semarang, Java Island, Indonesia

et al. 2014

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“…19 Meanwhile, an active hospital-based surveillance of IPD and pneumonia among children in Bali, Indonesia showed that no pneumococcus was identified from 736 subjects recruited during a period of 1 year. 20 These findings may indicate that the rate of blood culture positivity for pneumococcus is poor, despite the fact that microbiological confirmation is needed for IPD diagnosis. Some possible causes of this issue are prior antibiotic use, fastidious characteristic of the bacteria (particularly toward carbon dioxide), pneumococcal autolysis during the stationary phase, or technical errors during sample collection and handling.…”

Section: Discussionmentioning

confidence: 99%

Pediatric Invasive Pneumococcal Disease (IPD) in Yogyakarta, Indonesia: A Case Series

Arguni

Wijaya

Indrawanti

et al. 2022

Global Pediatric Health

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Given the fact that invasive pneumococcal disease (IPD) has a high clinical burden, particularly among children in developing countries, data on its occurrence and clinical profile in Indonesia is still insufficient. We presented 3 cases of IPD in children who were admitted to Dr. Sardjito General Hospital, Yogyakarta, Indonesia between 2016 and 2019. While our first 2 patients had milder course of disease, our third patient who presented with meningoencephalitis had poor outcome. Risk factors shown in our cases were young age and malignancy history. Multiple antibiotic resistance was observed in our isolates. The fact that none of our patients have received pneumococcal vaccination marks the necessity of this vaccine especially for at-risk children.

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“…The condition occurs primarily in cases of malnutrition with unhealthy environmental conditions (Health Office 2010). In Dr. Soetomo Hospital (period January 2007-December 2008 there are 66% of patients pneu-monia infant community with a mortality rate of 4% (Nata-prawira et al 2010, Purniti et al 2011, Setyoning-rum & Setiawati 2011, Asih et al 2011. The magnitude of the incident showed this age group susceptible to pneumonia due to weak/incomplete immune system and in patients suffering from recurrent infections occurs as a result of a defect complex system of defense mechanisms (PrabhuDas et al 2011, Jesenak et al 2011.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Antibiotics Use in Pediatric Pneumonia Patients Aged 3 Months - 5 Years

Aryani¹,

Hasmono²,

Zairina³

et al. 2017

FMI

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Surveilan Pneumokokus dan Dampak Pneumonia pada Anak Balita

Cited by 3 publications

References 1 publication

Nasopharyngeal Carriage of Streptococcus pneumonia in Pneumonia-Prone Age Groups in Semarang, Java Island, Indonesia

Nasopharyngeal Carriage of Streptococcus pneumonia in Pneumonia-Prone Age Groups in Semarang, Java Island, Indonesia

Pediatric Invasive Pneumococcal Disease (IPD) in Yogyakarta, Indonesia: A Case Series

Analysis of Antibiotics Use in Pediatric Pneumonia Patients Aged 3 Months - 5 Years

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