Surfactant enhanced liquid-phase microextraction of basic drugs of abuse in hair combined with high performance liquid chromatography

Yazdi, Ali Sarafraz; Es’haghi, Zarrin

doi:10.1016/j.chroma.2005.07.110

Cited by 94 publications

(10 citation statements)

References 39 publications

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“…Typically, equilibrium times in LPME are faster and range from ∼30 min [23,33] to 6–7 h [25]. A slow transfer of LAS over the membrane/acceptor interface was previously suspected in SLM extraction of LAS [24].…”

Section: Resultsmentioning

confidence: 99%

“…Reversed micelle extraction of proteins requires extraction times of 24 h [35] to 100 h [36]. In surfactant enhanced LPME of drugs, maximum enrichment was reached after ∼40 min, but it was found that when the sample concentration of (nonionic) surfactant exceeded the critical micelle concentration, E decreased sharply [33]. The interpretation was that drugs were incorporated into the micelles, which could not completely pass the HF pores.…”

Section: Resultsmentioning

confidence: 99%

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Liquid Phase Micro-Extraction of Linear Alkylbenzene Sulfonate Anionic Surfactants in Aqueous Samples

et al. 2011

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Hollow fiber liquid phase micro-extraction (LPME) of linear alkylbenzene sulfonates (LAS) from aqueous samples was studied. Ion pair extraction of C10, C11, C12 and C13 homologues was facilitated with trihexylamine as ion-pairing agent, using di-n-hexylether as solvent for the supported liquid membrane (SLM). Effects of extraction time, acceptor buffer concentration, stirring speed, sample volume, NaCl and humic acids were studied. At 10–50 μg L−1 linear R2-coefficients were 0.99 for C10 and C11 and 0.96 for C12. RSD was typically ∼15%. Three observations were especially made. Firstly, LPME for these analytes was unusually slow with maximum enrichment observed after 15–24 h (depending on sample volume). Secondly, the enrichment depended on LAS sample concentration with 35–150 times enrichment below ∼150 μg L−1 and 1850–4400 times enrichment at 1 mg L−1. Thirdly, lower homologues were enriched more than higher homologues at low sample concentrations, with reversed conditions at higher concentrations. These observations may be due to the fact that LAS and the amine counter ion themselves influence the mass transfer at the water-SLM interface. The observations on LPME of LAS may aid in LPME application to other compounds with surfactant properties or in surfactant enhanced membrane extraction of other compounds.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Liquid Phase Micro-Extraction of Linear Alkylbenzene Sulfonate Anionic Surfactants in Aqueous Samples

et al. 2011

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“…Then the remaining solid matrix was filtered and rinsed with 0.5 mL ethanol and added to the extracted solution. The remaining was diluted with appropriate deionized water .…”

Section: Methodsmentioning

confidence: 99%

Dispersive solid–liquid phase microextraction based on nanomagnetic Preyssler heteropolyacid: A novel method for the preconcentration of nortriptyline

Es’haghi

Hooshmand

2015

J of Separation Science

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In this study, a new, simple, rapid, and efficient method combined with ultraviolet visible spectrophotometry and high-performance liquid chromatography analysis was developed for the extraction and determination of nortriptyline. The tendency of the Preyssler tungsten heteropolyacid, H14 [NaP5 W30 O110 ], immobilized on the surface of mesoporous nanomagnetite to adsorb the drug from the solution has been investigated. This method involves the use of an appropriate mixture of nanosorbent that was homogenized in disperser solvent (1.0 mL, ethanol). At first, the mixture containing the nanomagnetic sorbent and disperser solvent was injected into the aqueous sample, and a cloudy solution was formed. Subsequently, separation of the two phases was carried out using a magnet. In the second stage, analyte was desorbed from the sorbent by methanol as the optimal desorption solvent using sonication method. The elution solvent containing enriched analyte was introduced to the instruments for further analysis. Optimization of experimental conditions with respect to the extraction efficiency was investigated. The method was linear in the range of 25-5000, while the detection limit (LOD = 3SB /m) was 7.9 ng/mL and the limit of quantification (LOQ = 10SB /m) was 26.4 ng/mL. The relative standard deviation was 4.66%. The method was successfully applied to human hair samples.

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“…A new approach is the analysis of fatty acid ethyl esters in hair specimens as possible markers of chronically elevated alcohol consumption by HS-SPME followed by GC/MS [79][80][81], another marker substance in hair being ethyl glucuronide [82][83][84][85]. Recently, with surfactant enhanced liquid-phase microextration (SE-LPME) an alternative concept for three-phase microextraction was introduced [86].…”

Section: Alternative Sample Preparation Techniquesmentioning

confidence: 99%

New trends in hair analysis and scientific demands on validation and technical notes

Mußhoff

Madea

2007

Forensic Science International

116

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Surfactant enhanced liquid-phase microextraction of basic drugs of abuse in hair combined with high performance liquid chromatography

Cited by 94 publications

References 39 publications

Liquid Phase Micro-Extraction of Linear Alkylbenzene Sulfonate Anionic Surfactants in Aqueous Samples

Liquid Phase Micro-Extraction of Linear Alkylbenzene Sulfonate Anionic Surfactants in Aqueous Samples

Dispersive solid–liquid phase microextraction based on nanomagnetic Preyssler heteropolyacid: A novel method for the preconcentration of nortriptyline

New trends in hair analysis and scientific demands on validation and technical notes

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