“Study of Total Cholesterol (Tc), Triacylglycerols (Tg), High Density Lipoprotein Cholesterol (Hdl-C) in Type Ii Diabetes Mellitus.”

Abstract

Objective: There are probably 100 million people in the world with diabetes mellitus (DM), and incidences of diabetes are on the rise. Dyslipidemia is one of the common disorders which are seen in most of the diabetes patients, which causes cardiovascular disorders. The aim of this study is to investigate the total cholesterol (TC), triacylglycerols (TGs), high-density lipoprotein cholesterol (HDL-C) in Type 2 DM, and healthy controls. Methods:The study was conducted on 50 controls and 50 Type 2 diabetic subjects between age group of 30 and 60 years. Serum TC was determined by an enzymatic (cholesterol oxidase/phenol-aminophenazone [PAP]) colorimetric method and TGs were determined by an enzymatic (glycerol phosphate oxidase-PAP) method, and HDL-C was estimated by a precipitant method. Statistical analysis was done using unpaired t-test. Results:The mean value of TC, TGs, and HDL-C in normal subjects is 165.5±24.24, 118.7±41.58, 28.38±7.85 mg/dl, respectively, and the value of TC, TGs, and HDL-C in diabetic patients is 179±31.69, 164.35±27.93, 25.4±6.86 mg/dl, respectively. The observed difference in the means of TC, TGs, and HDL-C in normal and diabetic are statistically significant (p<0.05). Conclusion:From the present study, it is concluded that TC, TGs, and HDL-C levels for all persons with Type 2 DM should be done as a routine test. Furthermore, early diagnosis and treatment of dyslipidemia can be used as a preventive measure for the development of cardiovascular disease in Type 2 diabetes.

Systemic Review: Sexual Dysfunction in Women with type 2 Diabetes Mellitus

“…Another major reason that potentiates the risk of sexual impairment is social, cultural risk factor which consists of financial issues, limited social relations, employment status and lack of exercise (Peng et al, 2005). Apart from this, there are other factors that contribute to the development of sexual dysfunction such as aging, (Bhasin et al, 2007) cardiovascular diseases, (Maiorino et al, 2014) Hypertension, (Park et al, 2002) genitourinary disease (Feldhaus-Dahir, 2009) and many more chronic diseases (Patil et al, 2017;Kim and Son, 2006). Diabetes mellitus itself is responsible for the high incidence of sexual problems.…”

Virtual Screening and Molecular Dynamics Simulation of Compounds From the Herbal Database of Indonesia Against Histone Deacetylase 2

“…Diabetes mellitus is a metabolic disorder caused by insufficient insulin production or the inability of the body to effectively use the insulin produced, resulting in an increase of glucose concentration in the blood (called hyperglycemia) [4]. This is due to the fact that insulin performs as a hormone that regulates blood sugar balance and does not work properly [5].…”