Study of lipid profile in adult women with acne

Abstract

ObjectiveThe aim of this study was to establish the lipid profile of female patients with acne in the Acne-in-Adult-Women Ambulatory Care Clinic in order to observe the prevalence of dyslipidemia in those patients.MethodsThis is a retrospective transversal study that evaluated the medical records of 416 patients who attended at the Acne-in-Adult-Women Ambulatory Care Clinic, at the Dermatology Department, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil, in the year 2012. Relevant data included age and clinical classification of acne. The lipid profile was analyzed according to the results of laboratory tests ordered during outpatient visits, which included total and fractionated cholesterol levels and triglycerides.ResultsThe epidemiological study sample was of 219 patients, with ages ranging from 21 to 61 years (mean of 32.23 years). The predominant clinical grade was papule-pustule acne (grade II) with 156 patients (71%). Regarding the lipid profile of the patients, there was a high increase in total cholesterol levels in 17.35% of the cases. High-density lipoprotein levels were low in 11.42% of the patients, with normal prevalence in 194 subjects. Low-density lipoprotein levels were normal in most patients (60.27%). Very-low-density lipoprotein values were normal in almost all patients (94.06%) and increased in only 13 patients (5.94%). Only 18 patients presented high levels of triglycerides (8.22%).ConclusionThe conclusion was that patients with grades II and III acne are more likely to have total cholesterol and low-density lipoprotein altered. A correct and early diagnosis can be an important measure for the prevention of the metabolic syndrome in these patients.

<p>Correlation Between Lipid Profile and Acne Vulgaris</p>

“…Furthermore, he said there was no significant difference between the grade of acne and patients' lipid profile, which was in agreement with our result. 23 As mentioned above, many studies have revealed lipid profile changes in acne patients, but, on the other hand, a few other studies showed similar values for lipid profile parameters in patients and controls. Ekiz et al reported that there was no relationship between acne and thyroid function, TG, TC, and LDL.…”

Biochemical and hormonal abnormalities in adult female acne

“…We did not find any statistically significant association between acne severity and lipid profile. Romanska‐Gocka et al 29 and da Cunha et al 6 in their studies reported no association between acne severity and lipid profile. Our results were consistent with their results.…”

“…Our results were consistent with their results. However, both these studies included patients with age ≥20 years 6,29 …”

“…In past few years, acne is considered as a chronic systemic disease, rather than a transient pubertal dermatological disease 5 . Lipid alterations like high serum total cholesterol (TC), triglycerides (TG) and low high density lipoprotein (HDL) have also been linked to acne 6 …”

“…5 Lipid alterations like high serum total cholesterol (TC), triglycerides (TG) and low high density lipoprotein (HDL) have also been linked to acne. 6…”