&lt;p&gt;Correlation Between Lipid Profile and Acne Vulgaris&lt;/p&gt;

Sobhan, Mohammadreza; Seifrabiei, Mohammad Ali; Amerifar, Maryam

doi:10.2147/ccid.s230617

Cited by 19 publications

(21 citation statements)

References 30 publications

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“…This was in concur with Sobhan et al, [20] who found that for cholesterol, a huge distinction was seen between male patients and solid partners (173.9±0.13 and 150.3±0.33 for patients and controls, separately, p=0.04).…”

Section: Discussionsupporting

confidence: 92%

“…In negate with Al Kubaisy et al, [19] who made a cross-sectional investigation led in the Syrian International University for Science and Technology, an example of 500 understudies was picked and discovered that guys have higher predominance of skin break out contrasted with females (42.9% versus 23.6%).Sobhan et al, [20] uncovered that the male to female proportion was about 1:2, however this was not factually huge (P=0.5). Li et al, [21] confirmed in their a meta-examination which was directed in terrain China found a higher pervasiveness pace of skin inflammation in guys than females, because of contrasts in way of life, skincare schedules, and androgen levels.Well, [22] uncovered that Over 90% of guys and 80% of females have encountered skin inflammation by the time of 21.Tan and Bhate, [23] study results uncovered that male patients were all the more oftentimes influenced, especially with more serious types of acne.This doesn't imply that skin inflammation is more normal in female yet it implies that young ladies are more mindful about their facial appearance than young men, and they look for treatment.…”

Section: Discussionmentioning

confidence: 95%

“…Each was inferred by increasing the factor for every district; (factor for temple and each cheek was 2, jawline and nose was 1 and chest and upper back was 3); by the most vigorously weighted sore inside every locale (1 for comedones, 2 for papules, 3 for pustules and 4 for knobs). A score of (1-18) is viewed as mellow; (19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30) moderate; (31)(32)(33)(34)(35)(36)(37)(38) serious; and >39 extreme (9)All studied subjects were tested for:  Serum level of Betatrophin.  Serum fasting insulin level.…”

Section: Patient and Methodsmentioning

confidence: 99%

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Assessment of Serum Level of Betatrophien in Acne Vulgaris Patient

Eleswy

El-Habbak

Khashba

et al. 2020

Benha Journal of Applied Sciences

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Acne, also known as acne vulgaris (AV), is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin. The investigation is expected to evaluate serum level of betartophien protein in patients with skin break out vulgaris and contrast it with its level in solid control. This is A case -control study, was led on 80 patients isolated into 2 groups:(Group A); 60 patients experiencing skin break out vulgaris, (Group B); 20 obviously sound people of coordinated age and sex. All examined subjects were tried forSerum level of Betatrophin. Higher betatrophien level was altogether connected with higher seriousness higher betatrophien level was fundamentally connected with male sexual orientation, PCOD, hairsuitism, androgenetic alopecia. The betatrophien level in AV bunch was essentially higher when contrasted with control gathering . Betatrophien level was proposed to be autonomous indicator of AV defenselessness and seriousness.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 95%

Section: Patient and Methodsmentioning

confidence: 99%

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Assessment of Serum Level of Betatrophien in Acne Vulgaris Patient

Eleswy

El-Habbak

Khashba

et al. 2020

Benha Journal of Applied Sciences

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“…Like our outcomes, Sobhan et al, [9] contemplated lipid profile anomalies in 45 skin inflammation vulgaris patients and 45 solid controls. They referenced that fundamentally more elevated cholesterol level in skin break out patients.…”

Section: Discussionsupporting

confidence: 55%

Evaluation of Serum Chemerin Level in Patients with Acne Vulgaris

Sanad

Ibrahim

Haleem

et al. 2021

Benha Journal of Applied Sciences

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Skin break out vulgaris is a constant cutaneous issue including brokenness of the pilosebaceous unit and is among the most well-known dermatological conditions around the world, with an expected 650 million individuals influenced. Serum chemerin is an adipokine that partakes in the resistant reaction by means of guideline of adipocyte improvement and metabolic capacity. Chemerin applies a critical impact on various resistant cell lines like NKs and DCs. In this way, serum chemerin was accounted for to apply a urgent job in a few provocative sicknesses. The investigation expected to assess serum level of Chemerin in patients with skin break out vulgaris. In addition, investigation of lipid profile boundaries and BMI was performed. The current examination included 50 skin inflammation vulgaris patients and 30 sound control subjects. Assessment of serum level of Chemerin in members and control bunches by protein connected immunosorbent measure (ELISA). Assessment of a lipid profile will be done in patients and control gatherings. Results and end: The base age in the skin inflammation bunch was 16 and the most extreme was 33, while the mean was 24.2 ± 5. The base age in the benchmark group was 17 and the greatest was 35, while the mean was 23.4 ± 4. Serum chemerin was fundamentally higher in skin break out patients contrasted with control subjects and was emphatically corresponded to seriousness of skin break out vulgaris. Assessment of serum lipid profile uncovered that skin inflammation patients had essentially serum cholesterol, TAG, LDL and fundamentally lower HDL contrasted with controls. In addition, skin inflammation patients had essentially higher BMI.

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“…Hence, the relationship of diet and acne development is still disputed ( Bowe et al, 2010 ).The importance of sebaceous glands in acne pathogenesis and evidence that its activity is modulated by dietary lipids provoked many researchers to study association of serum lipids in acne patients ( Sobhan et al, 2020 ). Recently, elevated expression of apolipoprotein a (apo-a), a core protein component of high density lipoprotein cholesterol (HDL-C) has been identified in a proteome analysis of the follicle infundibulum in acne patients ( Bek-Thomsen et al, 2014 ) Increased levels of total cholesterol (TC), but decreased levels of HDL-C and apo-a were consistently observed in acne patients from different populations ( Jiang et al, 2015 , Sobhan et al, 2020 ). In addition, El-Akawi and colleagues reported that serum HDL-C levels decrease with increase in acne severity ( El-Akawi et al, 2007 ).…”

Section: Introductionmentioning

confidence: 99%

Association of TNF-α polymorphisms (−857, −863 and −1031), TNF-α serum level and lipid profile with acne vulgaris

Younis

Shamim

Nisar

et al. 2021

Saudi Journal of Biological Sciences

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Background Acne is an inflammatory condition principally affected by genetic and dietary factors. Investigation into functional polymorphisms of TNF-α gene and their association with acne vulgaris will be helpful in exploring genetic influence on skin immune mediated inflammatory events. In the present study, we analyzed association of TNF-α gene polymorphisms, its expression levels and lipid profiles in a large cohort of acne patients and controls. Methods We used PCR-RFLP to study association of TNF-α polymorphisms at −857C/T, −863C/A and −1031 T/C sites with acne vulgaris. Lipid profiles were measured using enzymatic end-point method. The serum levels of TNF-α and apolipoprotein a were measured using ELISA. NIH, LDlink was used to investigate patterns of linkage disequilibrium across south Asian reference genome (Punjabi from Lahore Pakistan). Results We found that TNF-α −863 polymorphism is strongly associated with acne in overall population as well as in gender and severity based groups of acne patients. Polymorphisms at −863 and −1031 position were in linkage disequilibrium. Importantly, TNF-α serum level was significantly increased in acne patients with severe disease symptoms. Furthermore, levels of total cholesterol (TC) and triglycerides (TG) were significantly increased, whereas high density lipoprotein cholesterol (HDL-C) level was significantly decreased in acne patients. The levels of apolipoprotein a varied widely in studied populations and no significant difference was found in the analyzed groups. Conclusion In conclusion, we found that TNF-α expression increases in acne patients affected by TNF-α polymorphisms, and that the lipid profile is specifically disrupted in acne patients.

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<p>Correlation Between Lipid Profile and Acne Vulgaris</p>

Cited by 19 publications

References 30 publications

Assessment of Serum Level of Betatrophien in Acne Vulgaris Patient

Assessment of Serum Level of Betatrophien in Acne Vulgaris Patient

Evaluation of Serum Chemerin Level in Patients with Acne Vulgaris

Association of TNF-α polymorphisms (−857, −863 and −1031), TNF-α serum level and lipid profile with acne vulgaris

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