Study of Blood Compatible Polymers I. Modification of Poly(vinyl alcohol)

Synthesis and Characterization of Chitosan-Polyvinyl Alcohol Blended with Cloisite 30B for Controlled Release of the Anticancer Drug Curcumin

“…Blending leads to an intermolecular interaction between two polymers and this improves mechanical strength of the blends. Kim and other research workers [7,8] have also supported these results. Due to possibility of interaction between -OH and -NH 2 groups in these two polymers, blending improves mechanical properties of the films.…”

“…Moreover, an increase in the intensity and a shift in the band associated with the bend vibration of the CH 2 (1406 cm -1 ) group was observed. As expected, because the blend crosslinking reaction was conducted at pH (4.00 ± 0.05), covalent chemical bonds have preferentially occurred in the chitosan amine groups and less in the PVA hydroxyl groups [7]. Chemical crosslinking of the chitosan/PVA blends can be explained by the Schiff base formation as verified by the 1634 and 1550 cm -1 bands associated with the C=N and NH 2 groups, respectively [8].…”

“…It comprises an unbranched chain consisting of β-(1, 4)-2-amino-2-deoxy-D-glucopyranose, and it is a unique basic linear polysaccharide [4,[7][8][9]. The hydrophilicity of the polymer due to amine functionality in most repeat units makes the polymer soluble in dilute acid [10].…”

Preparation and Characterization of Cassava Starch - Polyvinyl Alcohol nanocomposites for Control Drug Release of Paclitaxel

“…These new systems can hinder solubility problems, protect the drug from the external environment such as photodegradation and pH changes, while reducing dose dumping by controlling the release profile. Moreover, controlled targeting at the site of action and reduced time of exposure at non-targeting tissues in-creases the efficacy of treatments and reduce toxicity and side effects thus improving patient compliance and convenience (Jegal et al, 1999;Kamath et al, 1993;Kas et al, 1997;Mathew et al, 1992).…”

Preparation of a Chemical Polyblend Sizing Agent via Polymerization of Acrylic Acid with Polyvinyl Alcohol

“…Graft copolymerization was extensively used to modify the properties of PVOH [6] . Grafting with methacrylic acid, AA, or acrylamide [7][8][9] improved the mechanical properties of sized sample and enhanced their desizability.…”