Synthesis and Characterization of Chitosan-Polyvinyl Alcohol Blended with Cloisite 30B for Controlled Release of the Anticancer Drug Curcumin

Parida, Umesh Kumar; Nayak, A.; Binhani, Birendra Kumar; Nayak, Padma L.

doi:10.4236/jbnb.2011.24051

Cited by 121 publications

(67 citation statements)

References 32 publications

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“…The bands at 1595 and 1658 cm -1 ascribed to bending variation of the N-H (N-acetylated residue, amide II band) and the carbonyl (C=O) stretching in amide I, respectively [32]. The absorption bands at 2877 cm -1 related to typical stretching of C-H [39]. and the peaks at 3179 cm -1 pertaining to O-H stretching and N-H stretching of chitosan [32].…”

Section: Ft-ir Analysismentioning

confidence: 97%

“…The bands at 1640 and 1692 cm -1 are connected to C=O stretching of chitosan. The peaks at 2881 cm -1 attributed to typical stretching of C-H and eventually the collected peaks at 3169, 3282 and 3422 cm -1 belong to N-H symmetrical vibrations concerned with amide II that exists in N-acetyl glucosamine unit of chitosan and vibration of O-H in chitosan and additive materials [39]. In both hydrogel samples after NaOH addition, the intensity of C-O bands with the centrality ~1090 cm -1 and C-H bands with the centrality ~2880 cm -1 became low; because CH3COONa salt is formed by NaOH addition and the intensity of C-O an C-H peaks decreased.…”

Section: Ft-ir Analysismentioning

confidence: 98%

“…The bands at 1640 and 1697 cm -1 connected to C=O stretching of chitosan. The peaks at 2871 cm -1 related to stretching of C-H and finally the accumulated peaks at 3182, 3293 and 3421 cm -1 belong to N-H symmetrical vibrations concerned with Amide II that exists in N-acetyl glucosamine unit of chitosan and vibration of O-H of chitosan [39] and additive materials. FTIR spectra of MH hydrogel showed bands at 518, 643, 833 and 1022 cm -1 attributed to bending and symmetric stretching of PO 4 3-and P-O of the used buffer and also culture medium in this hydrogel.…”

Section: Ft-ir Analysismentioning

confidence: 99%

See 2 more Smart Citations

pH-Sensitive Chitosan Hydrogel with Instant Gelation for Myocardial Regeneration

Alimirzaei¹,

Vasheghani‐Farahani²,

Ghiaseddin³

et al. 2017

J Tissue Sci Eng

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Section: Ft-ir Analysismentioning

confidence: 97%

Section: Ft-ir Analysismentioning

confidence: 98%

Section: Ft-ir Analysismentioning

confidence: 99%

See 1 more Smart Citation

pH-Sensitive Chitosan Hydrogel with Instant Gelation for Myocardial Regeneration

Alimirzaei¹,

Vasheghani‐Farahani²,

Ghiaseddin³

et al. 2017

J Tissue Sci Eng

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“…Its properties mainly depend on the degree of hydrolysis [6]. Its non-toxicity, water-solubility, biocompatibility and biodegradability make it widely applicable in biomedical field [11][12][13][14][15].…”

Section: Fabrication and Characterization Of Biodegradable Poly(vinylmentioning

confidence: 99%

Fabrication and Characterization of Biodegradable Poly(vinyl alcohol)/Chitosan Blends

Pokhrel¹,

Adhikari²,

Yadav³

2017

Asian J. Chem.

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Poly(vinyl alcohol)/chitosan (PVA/CS) blends were prepared by solution casting method using glutaraldehyde as a cross linking agent. Fourier transform infrared spectroscopy (FTIR) and microhardness technique were employed to study the intermolecular interactions between constituents of polymer blends and mechanical properties respectively. The degradation properties of PVA/CS films were studied by composting method. FTIR spectra of poly(vinyl alcohol) and PVA/CS blends showed some variations in the absorption bands which reflected interactions between the components of blends. The mechanical stiffness of PVA/CS blends was enhanced by chitosan upto 40 % loading and it was found optimum composition for the maximum enhancement of mechanical properties of the blend. The degradation rate of blends was found increased with the increase in chitosan content.

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“…All chitosan-derived blends cross-linked with GA, have shown the presence of the imine (C=N) band. The imine band was formed by the nucleophilic reaction of the amine from chitosan with the aldehyde group of GA. 31 Due to imine band instability with temperature and pH, this group can transform to a C-N group. 32 …”

Section: Atr-ftir Analysismentioning

confidence: 99%

Chemical cross-linking of chitosan/polyvinyl alcohol electrospun nanofibers

Pouranvari¹,

Ebrahimi²,

Javadi³

et al. 2016

Mater. Tehnol.

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Electrospun nanofibrous scaffolds have great potential for many biomedical applications. In the present study, we fabricated and characterized chitosan/polyvinyl alcohol (Chi/PVA) nanofibrous scaffolds through electrospinning. Cross-linking was performed using chemically with 5 % glutaraldehyde vapor. The morphology and chemical banding of the electrospun nanofibers before and after cross-linking were evaluated using scanning electron microscopy (SEM) and Attenuated Total ReflectanceFourier Transform InfraRed (ATR-FTIR) spectroscopy. SEM micrographs and FTIR spectra showed that the cross-linking process was accomplished successfully. With the biocompatibility and non-toxicity of chitosan and PVA, it is expected that this electrospun nanofibrous scaffold could be an excellent candidate for biomedical applications. Keywords: electrospinning, chitosan, polyvinyl alcohol, cross-linking Mre`e iz elektro spredenih nanovlaken imajo velik potencial za uporabo v biomedicini. V {tudiji smo izdelali in karakterizirali nanovlaknasto mre`o, izdelano z elektro predenjem nanovlaken iz hitosan/polivinil alkohola (Chi/PVA). Zamre`enje je bilo izdelano s pomo~jo kemijske metode s 5 % glutaraldehidne pare. Morfologija in kemijsko povezovanje elektro predenih nanovlaken, pred in po zamre`enju, sta bila ocenjena z uporabo vrsti~nega elektronskega mikroskopa (SEM) in z metodo z oslabljenim odbojem infrarde~e spektroskopije s Fourierjevo transformacijo (ATR-FTIR). SEM-posnetki in FTIR-spekter sta pokazala, da je bil postopek zamre`enja uspe{no dose`en. Glede na biokompatibilnost in netoksi~nost hitosana in PVA se pri~akuje, da bodo mre`e iz elektro spredenih nanovlaken odli~en element za uporabo v biomedicini.

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Synthesis and Characterization of Chitosan-Polyvinyl Alcohol Blended with Cloisite 30B for Controlled Release of the Anticancer Drug Curcumin

Abstract: ABSTRACT

Cited by 121 publications

References 32 publications

pH-Sensitive Chitosan Hydrogel with Instant Gelation for Myocardial Regeneration

pH-Sensitive Chitosan Hydrogel with Instant Gelation for Myocardial Regeneration

Fabrication and Characterization of Biodegradable Poly(vinyl alcohol)/Chitosan Blends

Chemical cross-linking of chitosan/polyvinyl alcohol electrospun nanofibers

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