Staphylococcus warneri endocarditis after implantation of a lumbar disc prosthesis in an immunocompetent patient

Clonality, virulence and the occurrence of genes encoding antibiotic resistance among Staphylococcus warneri isolates from bloodstream infections

“…Coagulase-negative Staphylococcus warneri is an opportunistic pathogen causing severe infections such as bacteraemia, endocarditis, vertebral osteomyelitis, ventriculoperitoneal shunt-associated meningitis, discitis, subdural empyema, urinary tract infections and sepsis in neonates (Kloos & Schleifer, 1975;Kamath et al, 1992;Torre et al, 1992;Wood et al, 1992;Buttery et al, 1997;Mehr et al, 2002;Announ et al, 2004;Stöllberger et al, 2006;Arslan et al, 2011;Legius et al, 2012). These infections occur predominantly in immunocompromised patients and those with indwelling medical devices (Arciola et al, 2005;von Eiff et al, 2006).…”

An Unusual Presentation of Endocarditis Caused by Staphylococcus warneri

“…These incidences often involved certain medical devices, such as the insertion of prosthetic heart valves or shunts in immunosuppressed patients [1, 6]. One clinical case described an unusual endocarditis from an immunocompetent individual who had a native aortic valve that was contaminated with S. warneri, and a prosthetic lumbar disc implanted 26 months prior was suggested as the probable source of infection [5]. Apparently there was precedence of another endocarditis case which developed one year after the implantation of a hip prosthesis [6].…”

Sepsis with multiple abscesses caused by staphylococcus warneri: a case report

“…Therefore, although previous intravenous drug abuse may have constituted a risk factor, we believe that recent intravenous drug abuse was not the route of infection in our patient. Most patients with invasive S. warneri infection have a subacute or even quite insidious course of disease [3,5,6,10]. In contrast, our patient presented with acute disease that did not differ from sepsis caused by more virulent coagulase-positive staphylococci.…”

“…On Gram stain, it appears as gram-positive cocci forming spherical cells in tetrads and clusters [2]. Like other coagulase-negative staphylococci, S. warneri generally causes infections in individuals with heart valve prostheses, cerebrospinal fluid derivation shunts, orthopedic endoprostheses, and peripheral and central venous catheters, in particular in the intensive care unit setting [3][4][5][6][7][8]. A case of Staphylococcus warneri sepsis with multiple abscesses in an immunocompetent patient free from risk factors for coagulase-negative staphylococcal infection is presented.…”