Special Micronutrient Concerns in Premature Infants: Implications for Enteral and Parenteral Feeding

Sh, Zlotkin

doi:10.1159/000074725

Cited by 4 publications

(4 citation statements)

References 15 publications

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“…While physiologically serum zinc levels also decrease in 0 to 6-month-old babies due to the decreasing amounts of zinc in breast milk, while less zinc is stored in the body. 8,13 This result differed from other research conducted by Diaz-gomez et al, 8 in which 5 mg zinc supplementation was given to preterm infants. After three months of supplementation, the serum zinc level increased significantly from 69 (SD 20) μg/ dL to 113 (SD 25) μg/dL (P=0.003).…”

Section: Figurementioning

confidence: 63%

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Linear growth patterns in small for gestational age and preterm infants after zinc supplementation

Setiawan

Sarosa

Setiawati

2015

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Background Low birth weight (LBW) infants are at risk for growth disturbances due to intrauterine zinc deficiency. Zinc supplementation is expected to improve the linear growth of LBW babies.Objective To assess the effect of zinc supplementation on linear growth in preterm and small for gestational age (SGA) infants.Methods This quasi-experimental study had a pre-and post-test design. Subjects were LBW infants hospitalized in Kariadi Hospital during March-December 2011, consisted of SGA and preterm neonates. All subjects were given 5 mg of zinc syrup daily for 3 months. Subjects' head circumference, weight, and length were measured monthly. Serum zinc levels were measured before and after supplementation. Data were analyzed with Chi-square test, independent T-test, and general linear model repeated measure.Results A total of 61 subjects were enrolled consisted of 31 preterm and 30 SGA neonates. Mean serum zinc levels in the preterm group were 168.2 (SD 54.5) μg/dL pre-supplementation and 163.6 (SD 50.7) μg/dL post-supplementation (P=0.049), while mean serum zinc levels in the SGA group were 174.8 (SD 46.6) μg/dL pre-supplementation and 167.4 (SD 49.4) μg/dL post-supplementation (P=0.271). Median percentage preterm weight and length increased from 87.3 to 102.4% in the third month (P<0.001) and from 95.8 to 103.9% in the third month (P<0.001), respectively. Median percentage SGA weight and length increased from 73.5 to 98.3% in the third month (P<0.001) and from 94.5 to 102.2% in the third month (P<0.001), respectively. ConclusionBoth, the preterm and SGA infants exhibit catch-up growth after three months of zinc supplementation. [Paediatr Indones. 2015;55:23-8.].

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Section: Figurementioning

confidence: 63%

“…5 Zinc toxicity may be detected by clinical manifestations such as nausea, epigastric pain, diarrhea, lethargy, and muscle pain. 13 Serum zinc levels in subjects remained below the maximum daily level and there were no toxicity clinical manifestations in subjects during monitoring.…”

Section: Figurementioning

confidence: 88%

Linear growth patterns in small for gestational age and preterm infants after zinc supplementation

Setiawan

Sarosa

Setiawati

2015

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“…Zinc is an essential trace mineral that is intricately associated with growth and development (2)(3)(4). It is of particular importance in vulnerable populations such as ELBW infants who have rapid growth and periods of critical illness (17,33,34).…”

Section: Discussionmentioning

confidence: 99%

“…None of the infants in our study displayed classic signs of zinc deficiency. It is possible, however, that they had subclinical zinc deficiency, a condition that has been of concern in preterm infant nutrition (34,43,44).…”

Section: Discussionmentioning

confidence: 99%

Enteral Zinc Supplementation and Growth in Extremely‐Low‐Birth‐Weight Infants With Chronic Lung Disease

Shaikhkhalil

Curtiss

Puthoff³

et al. 2014

J. pediatr. gastroenterol. nutr.

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Objective Zinc deficiency causes growth deficits. Extremely-low-birth-weight (ELBW) infants with chronic lung disease (CLD), also known as bronchopulmonary dysplasia, experience growth failure and are at risk for zinc deficiency. We hypothesized that enteral zinc supplementation would increase weight gain and linear growth. Methods A cohort of infants was examined retrospectively at a single center between January 2008 and December 2011. CLD was defined as the need for oxygen at 36 weeks postmenstrual age. Zinc supplementation was started in infants who had poor weight gain. Infants’ weight gain and linear growth were compared before and after zinc supplementation using the paired t test. Results A total of 52 ELBW infants with CLD met entry criteria. Mean birth weight was 682 ± 183 g, and gestational age was 25.3 ± 2 weeks. Zinc supplementation started at postmenstrual age 33 ± 2 weeks. Most infants received fortified human milk. Weight gain increased from 10.9 before supplementation to 19.9 g · kg−1 · day−1 after supplementation (P < 0.0001). Linear growth increased from 0.7 to 1.1 cm/week (P = 0.001). Conclusions Zinc supplementation improved growth in ELBW infants with CLD receiving human milk. Further investigation is warranted to reevaluate zinc requirements, markers, and balance.

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Chromium content in different kinds of Spanish infant formulae and estimation of dietary intake by infants fed on reconstituted powder formulae

Sola-Larrañaga¹,

Navarro-Blasco²

2006

Food Additives and Contaminants

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Special Micronutrient Concerns in Premature Infants: Implications for Enteral and Parenteral Feeding

Cited by 4 publications

References 15 publications

Linear growth patterns in small for gestational age and preterm infants after zinc supplementation

Linear growth patterns in small for gestational age and preterm infants after zinc supplementation

Enteral Zinc Supplementation and Growth in Extremely‐Low‐Birth‐Weight Infants With Chronic Lung Disease

Chromium content in different kinds of Spanish infant formulae and estimation of dietary intake by infants fed on reconstituted powder formulae

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