Silky Co₃O₄ nanostructures for the selective and sensitive enzyme free sensing of uric acid

Abstract

In this study, simple, new and functional silky nanostructures of Co3O4 are prepared by hydrothermal method.

Electrochemical Ultrasensitive Sensing of Uric Acid on Non-Enzymatic Porous Cobalt Oxide Nanosheets-Based Sensor

“…The achieved sensing performance results are shown in Table 1 . As shown in Table 1 , the cobalt oxide/GCE sensor showed ultra-high sensitivity compared to previously reported literature [ 11 , 24 , 30 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ]. Furthermore, the DPV technique showed ~7.58 times high sensitivity (3566.5 µAmM −1 cm −2 ) compared to CV’s measured sensitivity (470.4 µAmM −1 cm −2 ).…”

“…The XRD pattern confirms the crystalline nature of nanomaterial, and the obtained pattern is well indexed (JCPDS card no. 42-1467) [ 30 ]. The diffraction peaks of cobalt oxide are observed at 2Ɵ values of 22.1°, 31.1°, 36.6°, 38.1°, 44.6°, 55.4°, 59.6°, and 66.7°, corresponding to the miller indices of [111], [220], [311], [222], [400], [422], [511], and [440], respectively.…”

A non-enzymatic electrochemical sensor composed of nano-berry shaped cobalt oxide nanostructures on a glassy carbon electrode for uric acid detection

“…The CV curve shows a clear voltammetry (0.69 V) peak, ascribed to the uric acid oxidation. 30 A substantial response of the Co 3 O 4 nano-berry/GCE for uric acid was observed compared to the response in only buffer solution. This implies that Co 3 O 4 nano-berries fixed onto the GCE could oxidize uric acid effectively and increase the peak current.…”

“…The most acceptable detection mechanism involves two proton and electron transfer, which is shown in Scheme 2. 30,35,37 The unique nano-berry nanostructure of Co 3 O 4 provided a large surface area with abundant catalytic sites for uric acid oxidation. Another possible reason for non-enzymatic oxidation of uric acid could be the p-type semiconducting nature of Co 3 O 4 , which provided hole concentration in excess and resulted in easy capture of electrons from uric acid oxidation.…”

Hexagonal cobalt oxide nanosheet-based enzymeless electrochemical uric acid sensor with improved sensitivity

“…[13][14][15] Recently, different nanostructured materials (i.e., CeO 2 , Co 3 O 4 , CuO, Cu 2 O, Fe 2 O 3 , MgO, MnO 2 , MoS 2 , NiO, SnO 2 , and ZnO) have been used to fabricate electrochemical-based enzymeless UA sensors. [16][17][18][19] Among these nanomaterials, cobalt oxide has gained interest as an superior electrochemical material for electrodes and offers excellent catalytic properties. 20 Various morphologies of the cobalt oxide have been synthesised using chemical vapour deposition, sol-gel techniques, chemical precursor routes, and electrophoretic deposition techniques.…”