A non-enzymatic electrochemical sensor composed of nano-berry shaped cobalt oxide nanostructures on a glassy carbon electrode for uric acid detection

Abstract

Nanomaterials-based sensors are in demand for early-stage disease detection as a diagnostic tool. Here, we prepare a non-enzymatic electrochemical sensor using hydrothermally synthesized nano-berries shaped cobalt oxide (Co3O4) nanostructures on...

Electrochemical Ultrasensitive Sensing of Uric Acid on Non-Enzymatic Porous Cobalt Oxide Nanosheets-Based Sensor

“…The achieved sensing performance results are shown in Table 1 . As shown in Table 1 , the cobalt oxide/GCE sensor showed ultra-high sensitivity compared to previously reported literature [ 11 , 24 , 30 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ]. Furthermore, the DPV technique showed ~7.58 times high sensitivity (3566.5 µAmM −1 cm −2 ) compared to CV’s measured sensitivity (470.4 µAmM −1 cm −2 ).…”

“…The improved electro-catalytic activity and charge transfer capabilities of metal/metal oxide have attracted considerable interest for their applications in electrode modifications [ 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. Among different metal oxides, cobalt oxide nanomaterials have been utilized to fabricate enzymatic/non-enzymatic sensors where the use of cobalt oxide nanostructures enhances the desired electrochemical properties [ 23 , 24 , 25 , 26 , 27 , 28 , 29 ]. Different methods (i.e., thermal decomposition, sol-gel, surfactant-mediated synthesis, spray-pyrolysis, and polymer-matrix assisted) are utilized for the synthesis of various kinds of cobalt oxide nanostructures.…”

“…Recently, cobalt oxide has attained interest for different applications (i.e., heterogeneous catalysis, lithium-ion batteries, gas sensing, electrochemical sensors, and solar cells). Cobalt oxide nanostructures are the preferred material to modify the electrode, which offers abundant active sites for reaction and easy adsorption/electroactive species diffusion [ 24 ]. Hence, cobalt oxide nanostructures modified sensor electrodes are suitable for the detection of different analytes.…”

“…Hence, cobalt oxide nanostructures modified sensor electrodes are suitable for the detection of different analytes. For example, Nagal et al described the use of nano berry-like cobalt oxide nanostructures for the electrochemical-based enzyme-less uric acid sensor [ 24 ]. Kogularasu et al investigated the impact of cobalt oxide polyhedrons to develop an enzyme-free biosensor detect H 2 O 2 [ 25 ].…”

Novel ratiometric electrochemical sensing platform for uric acid based on electroactive cuprous oxide nanocubes combined with boron carbide

“…Even though GSH and l -Cys can interact with Cu 2 O to cause a small decrease in the Cu oxidation peak current, they do not change the oxidation peak current at 0.25 V. Moreover, the interferences can be masked by the addition of N -ethylmaleimide (NEM) when their contents are too high. 29 Therefore, the final ratio of I 2 / I 1 did not change significantly. Therefore, the results show that the sensor has good selectivity to UA.…”