Sign of Leser-Trélat and mycosis fungoides

McCrary, Monica L.; Davis, Loretta S.

doi:10.1016/s0190-9622(98)70143-4

Cited by 12 publications

(4 citation statements)

References 6 publications

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“…A few cases of cutaneous T-cell lymphoma associated with eruptive seborrheic keratoses have been reported [ 1 , 5 , 6 , 7 , 8 ]. Systemic lymphoma and leukemia were also associated with this manifestation in a recent review of the literature [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association

et al. 2018

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Sign of Leser-Trélat is a rare paraneoplastic cutaneous manifestation, characterized by the sudden appearance and rapid increase in size and number of seborrheic keratoses, accompanied by pruritus. Edmund Leser and Ulysse Trélat described this sign in 1890. Since their first description, their conclusions have been considered controversial and some authors assert the absence of a causal link. It seems to be frequently associated with solid tumors and in particular gastrointestinal cancer. Here, we describe a new case associated with a cutaneous T-cell lymphoma and a partial response to extracorporeal photopheresis.

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Section: Discussionmentioning

confidence: 99%

Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association

et al. 2018

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“…We identified 28 individuals with Leser-Trélat signassociated lymphoma and leukemia (Table 1, ) and summarized the characteristics of 15 patients-! A B [3][4][5][6][7][8][9][10][11][12][13][14][15][16]).…”

Section: Case Discussionmentioning

confidence: 99%

Cutaneous T-cell lymphoma-associated Leser-Trélat sign: report and world literature review

Narala

Cohen²

2017

Dermatology Online Journal

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“…Other reported associations include lung cancer, 40 melanoma, 41 and mycosis fungoides. 42 Because both seborrheic keratoses and cancer are prevalent in the elderly, the validity of Leser-Trélat sign has been questioned. 43 An association with malignant acanthosis nigricans has been proposed as one of the features that support the legitimacy of the sign as a paraneoplastic marker.…”

Section: Dermatologic Signsmentioning

confidence: 99%