Short‐term clinical effects of adjunctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial

Braun, Andreas; Dehn, Claudia; Krause, Felix; Jepsen, Søren

doi:10.1111/j.1600-051x.2008.01303.x

Cited by 256 publications

(278 citation statements)

References 45 publications

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“…In all cases except for GR, better results were obtained in the group treated with PDT; however, there was no difference in the recession in the 2 groups. 14 In another clinical trial that was conducted in 2008 by Christodoulides et al, 24 patients with chronic periodontitis were randomly divided into 2 groups: 1-treatment with SRP, 2-treatment with SRP and PDT (diode laser 670 nm and power of 75 mW) and no statistically significant difference was seen between the 2 groups, and only BOP showed significant improvements in the group treated with SRP and PDT, compared to the one treated with SRP alone. 15 In another clinical trial conducted in 2009 by Chondros et al, 24 patients with chronic periodontitis were divided into 2 groups: group 1-treatment by SRP and group 2-treatment with SRP and PDT (670 nm, 75 mW laser diode and photosensitizer phenothiazine chloride for 60 seconds), respectively.…”

Section: Review Of Literaturementioning

confidence: 99%

The Effect of Photodynamic Therapy in the Treatment of Chronic Periodontitis: A Review of Literature

et al. 2017

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Introduction: Chronic periodontitis is the most common periodontal disease which is related to the chronic accumulation of bacterial plaque. Since mechanical methods are not sufficient in the treatment of this disease, administration of local/systemic antibiotic is recommended following mechanical debridement. However, side effects of antibiotics such as microbial resistance and patient allergy led to development of alternative methods. One of these suggested methods is the antimicrobial photodynamic therapy (aPDT). PDT is a local noninvasive treatment modality without the side effects caused by antibiotics. The aim of this study was to review the articles related to the application of PDT with laser in the treatment of chronic periodontitis. Review of literature:In the present review of literature, the authors used key words such as chronic periodontitis, laser and photodynamic therapy, and conducted a literature search via Google Scholar and PubMed for the period of 1990 to 2015. A total of 47 articles in English were found. The articles that were not associated with the topic of research and review articles were deleted and only clinical trials were evaluated. After reviewing 23 articles' abstracts, the full texts of 16 articles were analyzed. Conclusion: Considering the safety, the lack of side effects and general advantages like more patient compliance, the PDT treatment with scaling and root planing (SRP) is recommended as an efficient adjunctive modality for the treatment of localized chronic periodontitis especially during the maintenance phase in non-surgical treatment.

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Section: Review Of Literaturementioning

confidence: 99%

The Effect of Photodynamic Therapy in the Treatment of Chronic Periodontitis: A Review of Literature

et al. 2017

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“…Eight out of the 18 studies have reported statistically significantly higher improvements in probing depth (PD) reduction and/or clinical attachment (CAL) gain following SRP + PDT compared to SRP alone, [21][22][23][24][25][26][27][28] _ENREF_22while the rest of 10 studies have failed to reveal statistically significant differences in these parameters. 29,[30][31][32][33][34][35][36][37][38] An additional improvement for the reduction of bleeding on probing (BOP) following the use of PDT was reported in 5 out of the 19 papers.…”

Section: Use Of Pdt As Adjunct To Nonsurgical Periodontal Therapy In mentioning

confidence: 99%

“…29,[30][31][32][33][34][35][36][37][38] An additional improvement for the reduction of bleeding on probing (BOP) following the use of PDT was reported in 5 out of the 19 papers. 22,26,28,31,32 Changes of microbiological parameters were evaluated in 8 of 18 studies. Four studies have found a statistically significant effect of the additional use of PDT on the reduction of periodontal pathogens, 28,35,37,38 while 4 studies have failed to reveal any differences between the treatments groups.…”

Section: Use Of Pdt As Adjunct To Nonsurgical Periodontal Therapy In mentioning

confidence: 99%

Is Photodynamic Therapy an Effective Treatment for Periodontal and Peri-Implant Infections?

Sculean

Aoki

Romanos

et al. 2015

Dental Clinics of North America

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“…The majority of reports indicate that PDT only results in decreasing the inflammation severity and there is insufficient evidence in relation to the effect of PDT on periodontitis. [35][36][37] Shibli et al 38 showed the effect of PDT on the pathogens within periodontal pockets. Meisel and Kocher 20 showed that the use of photosensitizing dyes and their activation with laser beams might result in the destruction of pathogens responsible for periodontal diseases and peri-implantitis.…”

Section: Effectiveness Of Photodynamic Therapy In Treatment Of Peri-imentioning

confidence: 99%

Evaluation of Effectiveness of Photodynamic Therapy With Low-level Diode Laser in Nonsurgical Treatment of Peri-implantitis

et al. 2017

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Introduction: Side effects related to antibiotic therapy for peri-implantitis are rare in laser therapy (LT); therefore, the aim of this study was to evaluate the effectiveness of LT and photodynamic therapy (PDT) on patients with primary peri-implantitis. Methods: In this randomized clinical trial, 40 implants presenting primary peri-implantitis in 20 patients with a mean age of 52.6 years old were included using the simple sampling technique. Periodontal treatment comprising scaling and root planing (SRP) was accomplished for the whole mouth while mechanical debridement with titanium curettes and air polishing with sodium bicarbonate powder was accomplished around the implants. The implants were randomly divided into two groups and treated with LT (control) and PDT (test). The clinical indices were measured at baseline, 6 weeks and 3 months after treatment. Real-time polymerase chain reaction (PCR) was used for analysis of microbial samples at baseline and 3-month follow-up. Data were analyzed with SPSS 20, using repeated-measures analysis of variance (ANOVA) and Friedman's and MannWhitney tests (α = 0.05). Results: Both groups showed statistically significant improvements in terms of bleeding on probing (P < 0.001), probing pocket depth (PPD) (P = 0.006) and modified plaque index (P < 0.001), with no significant differences between the 2 groups (P > 0.05). The number of Aggregatibacter actinomycetemcomitans (P = 0.022), Tannerella forsythia (P = 0.038) and Porphyromonas gingivalis (P = 0.05) in the test group and Porphyromonas gingivalis (P = 0.015) in the control group significantly decreased. Conclusion:The results suggested that LT and PDT have significant short-term benefits in the treatment of primary peri-implantitis.

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Short‐term clinical effects of adjunctive antimicrobial photodynamic therapy in periodontal treatment: a randomized clinical trial

Abstract: In patients with chronic periodontitis, clinical outcomes of conventional subgingival debridement can be improved by adjunctive aPDT.

Cited by 256 publications

References 45 publications

The Effect of Photodynamic Therapy in the Treatment of Chronic Periodontitis: A Review of Literature

The Effect of Photodynamic Therapy in the Treatment of Chronic Periodontitis: A Review of Literature

Is Photodynamic Therapy an Effective Treatment for Periodontal and Peri-Implant Infections?

Evaluation of Effectiveness of Photodynamic Therapy With Low-level Diode Laser in Nonsurgical Treatment of Peri-implantitis

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