Seroprevalence of toxoplasmosis in pregnant women

Varella, Ivana Rosângela dos Santos; Darela, Alessandra C.; Nunes, Leandro Meirelles; Müller, R; Wagner, Mário Bernardes

doi:10.2223/jped.940

Cited by 24 publications

(35 citation statements)

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“…Similar results were found in other regions of Brazil, e.g., 69.3% in Sergipe 6 , 73.5% in the indigenous Amazonas population 9 , and 59.8% in Porto Alegre 33 .…”

Section: Discussionsupporting

confidence: 88%

Epidemiologic aspects of toxoplasmosis and evaluation of its seroprevalence in pregnant women

Fonseca

Silva

Fux

et al. 2012

Rev. Soc. Bras. Med. Trop.

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answered a quantitative questionnaire; 49.5% were seropositive for immunoglobulin (Ig) G and 3.6% for IgM. Comparative analysis of congenital toxoplasmosis cases were evaluated in 11 regions and showed an irregular distribution (p < 0.01). This difference was also observed among the pregnant women observed in each location. The results from the questionnaire show that 93% of the pregnant women had no knowledge about toxoplasmosis, and 24% presented with positive serology, but no clinical manifestation. Analysis for pregnant IgG-positive women and the presence of pets showed a statistically significant correlation (p < 0.05), suggesting that the transmission of this disease might occur in the domestic environment. Conclusions: We suggest the implementation of a triage program for pregnant women and health education to encourage their use of SUS services.

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“…Similar results were found in other regions of Brazil, e.g., 69.3% in Sergipe 6 , 73.5% in the indigenous Amazonas population 9 , and 59.8% in Porto Alegre 33 .…”

Section: Discussionsupporting

confidence: 88%

Epidemiologic aspects of toxoplasmosis and evaluation of its seroprevalence in pregnant women

Fonseca

Silva

Fux

et al. 2012

Rev. Soc. Bras. Med. Trop.

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“…Regarding maternal age for acute exposure to Toxoplasma gondii during pregnancy, a mean age of 22.1 years was found, similar to the mean age of 23 years reported by Figueró et al and 26.3 years reported by Varella et al 11,12 . Although in disagreement with other studies, maternal schooling greater than 9 years was not found to be a protective factor against the disease 13,14 .…”

Section: Discussionsupporting

confidence: 87%

Profile of pregnant women and children treated at a reference center for congenital toxoplasmosis in the northern state of Minas Gerais, Brazil

Soares

Carvalho

Caldeira

2012

Rev. Soc. Bras. Med. Trop.

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Introduction:To describe the clinical and epidemiological profile of pregnant women and children treated at a reference outpatient clinic for congenital toxoplasmosis. Methods: Pregnant women potentially exposed to Toxoplasma gondii were observed. Diagnoses were made using serologic tests compatible with acute toxoplasmosis. Children presenting with: Toxoplasma-specific antibodies (IgM or IgA or ascending IgG titers higher than maternal titers in the first 3 months of life) coupled with toxoplasmosis symptoms; intracranial calcifications (by transfontanelar ultrasound or cephalic segment tomography); or retinochoroiditis (by fundoscopy examination) in the first 8 months of life were also included in the study. Results: Fifty-eight mother-child pairs were observed (mean age of the mothers was 22.1 years). Most patients lived in urban areas (86.2%) and had attended less than 8 years of school (51.7%). Diagnosis was made after birth in 19 (32.8%) children. Thirty-four (58.6%) women received some type of treatment during pregnancy. Most (72.4%) of the children did not present with clinical alterations at birth. The main findings were ophthalmological: 20 (34.5%) children with retinochoroiditis, 17 (29.3%) with strabismus, and 7 (12.1%) with nystagmus. Of the children with retinochoroiditis, 9 presented with subnormal vision. Ten (32.3%) out of 31 children presented with intracranial calcifications by cephalic segment congenital toxoplasmosis, and 9 (42.9%) children presented with delayed psychomotor development. Conclusions: Our results highlight a critical situation. Protocols for follow-up of pregnant women and their children must be created to improve medical care and minimize sequelae.

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“…Similar results were found in Porto Alegre (RS), São José do Rio Preto (SP) and Pelotas (RS), detecting 59.8%, 57.3% and 54.8%, respectively (Varella et al, 2003;Galisteu et al, 2007;Cademartori et al, 2008).…”

Section: Discussionsupporting

confidence: 73%

“…Congenital toxoplasmosis happens when primo-infection occurs in the mother during pregnancy and the parasite reaches the fetus through the placenta, causing damages of different severities, depending on the pregnancy age, strain virulence, immune response capability of the pregnant women, or pregnancy stage (Kasper, 2002;Spalding et al, 2003;Varella et al, 2003;Montoya and Rosso, 2005;Montaño et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Toxoplasmosis seroepidemiology in pregnant women in a city in the Northwest region of the Paraná State, Brazil

et al. 2017

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Toxoplasmosis seroepidemiology in pregnant women in a city in the Northwest AbstractToxoplasmosis is a zoonosis caused by the Toxoplasma gondii protozoa. The congenital form happens when the parasite reaches the fetus through the placenta and causes damages of different intensities, which can be consequence of the strain virulence, of the immune response capability of the pregnant woman or even of the pregnancy stage, and can result in fetal death or severe clinical symptomatology. The aim of this paper was to determine the prevalence of antibodies to Toxoplasma gondii antibodies in pregnant woman seen at the Basic Health Units (BHU) in the city of Umuarama (PR) and check for possible toxoplasmosis associations with social-demographic characteristics, behavior and environmental variables. In this study, a total of 813 pregnant women who had their prenatal exams at the BHU in the city of Umuarama (PR) were included. Blood samples collected from these subjects were submitted to IgG and IgM anti-T. gondii antibody survey. Each pregnant woman answered an epidemiological questionnaire for the detection of variables, which were later analyzed by the EpiInfo program. The prevalence detected for IgG and IgM anti-T. gondii antibodies were 56.8% and 1.0%, respectively. The variables age group, education level, per capita income, number of pregnancies, ingestion of fresh sausage, presence of peridomiciliary cats in the backyard and the habit of ingesting farm milk showed association to the infection by T. gondii.Keywords: Toxoplasma gondii; serology; zoonosis; public health, congenital toxoplasmosis. Resumo

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Seroprevalence of toxoplasmosis in pregnant women

Cited by 24 publications

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Epidemiologic aspects of toxoplasmosis and evaluation of its seroprevalence in pregnant women

Epidemiologic aspects of toxoplasmosis and evaluation of its seroprevalence in pregnant women

Profile of pregnant women and children treated at a reference center for congenital toxoplasmosis in the northern state of Minas Gerais, Brazil

Toxoplasmosis seroepidemiology in pregnant women in a city in the Northwest region of the Paraná State, Brazil

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