Separation of acidic compounds and determination of shikimic acid in water extracts of several conifers by HPLC

Zhang, Junmin; Shi, Xiao Feng; Fu, Si Wu; Zhao, Jin; Guo, Yu Lin

doi:10.1007/s10600-013-0718-6

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…Employing intensive extraction methods allows for a significant increase in extraction yields [106]. Following evaporation, the extracts are treated with activated carbon to obtain a purified material [107], although the use of ion exchange resins is more efficient. Anionexchange resins selectively absorb shikimic and other organic acids, which are subsequently desorbed using an alkaline eluent, followed by evaporation and crystallization [79].…”

Section: Preparation and Properties Of Aqueous Extractsmentioning

confidence: 99%

Strategy of Coniferous Needle Biorefinery into Value-Added Products to Implement Circular Bioeconomy Concepts in Forestry Side Stream Utilization

Klavins,

Almonaitytė,

Šalaševičienė

et al. 2023

Molecules

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Sustainable development goals require a reduction in the existing heavy reliance on fossil resources. Forestry can be considered a key resource for the bioeconomy, providing timber, energy, chemicals (including fine chemicals), and various other products. Besides the main product, timber, forestry generates significant amounts of different biomass side streams. Considering the unique and highly complex chemical composition of coniferous needle/greenery biomass, biorefinery strategies can be considered as prospective possibilities to address top segments of the bio-based value pyramid, addressing coniferous biomass side streams as a source of diverse chemical substances with applications as the replacement of fossil material-based chemicals, building blocks, food, and feed and applications as fine chemicals. This study reviews biorefinery methods for coniferous tree forestry biomass side streams, exploring the production of value-added products. Additionally, it discusses the potential for developing further biorefinery strategies to obtain products with enhanced value.

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Section: Preparation and Properties Of Aqueous Extractsmentioning

confidence: 99%

Strategy of Coniferous Needle Biorefinery into Value-Added Products to Implement Circular Bioeconomy Concepts in Forestry Side Stream Utilization

Klavins,

Almonaitytė,

Šalaševičienė

et al. 2023

Molecules

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“…The chemical constituents of pine needles of CD were investigated in our lab. More than 40 pure compounds, including lignans, flavonoids, phenolic compounds and their glycosides [10–16], were isolated from petroleum ether, ethyl acetate and n -butanol extracts of pine needles. The antitumor activity of isolated flavonoids was investigated in greater depth [17].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the anti-cancer potential of Cedrus deodara total lignans by inducing apoptosis of A549 cells

Shi

Zhang

et al. 2019

BMC Complement Altern Med

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BackgroundCedrus deodara (Roxb.) Loud (normally called as deodar), one out of four species in the genus Cedrus, exhibits widely biological activities. The Cedrus deodara total lignans from the pine needles (CTL) were extracted. The aim of the study was to investigate the anticancer potential of the CTL on A549 cell line.MethodsWe extracted the CTL by ethanol and assessed the cytotoxicity by CCK-8 method. Cell cycle and apoptosis were detected by a FACS Verse Calibur flow cytometry.ResultsThe CTL were extracted by means of ethanol hot refluxing and the content of total lignans in CTL was about 55.77%. By the CCK-8 assays, CTL inhibited the growth of A549 cells in a dose-dependent fashion, with the IC50 values of 39.82 ± 1.74 μg/mL. CTL also inhibited the growth to a less extent in HeLa, HepG2, MKN28 and HT-29 cells.ConclusionAt low doses, the CTL effectively inhibited the growth of A549 cells. By comparison of IC50 values, we found that A549 cells might be more sensitive to the treatment with CTL. In addition, CTL were also able to increase the population of A549 cells in G2/M phase and the percentage of apoptotic A549 cells. CTL may have therapeutic potential in lung adenocarcinoma cancer by regulating cell cycle and apoptosis.

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Compounds from Lotus corniculatus

Yang

Chen

et al. 2019

Chem Nat Compd

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Separation of acidic compounds and determination of shikimic acid in water extracts of several conifers by HPLC

Cited by 3 publications

References 11 publications

Strategy of Coniferous Needle Biorefinery into Value-Added Products to Implement Circular Bioeconomy Concepts in Forestry Side Stream Utilization

Strategy of Coniferous Needle Biorefinery into Value-Added Products to Implement Circular Bioeconomy Concepts in Forestry Side Stream Utilization

Evaluation of the anti-cancer potential of Cedrus deodara total lignans by inducing apoptosis of A549 cells

Compounds from Lotus corniculatus

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