Senyawa-Senyawa Bioaktif Pada Rumput Laut Cokelat Sargassum Sp. : Ulasan Ilmiah

Rohim, Abdul; Yunianta,; Estiasih, Teti

doi:10.21776/ub.jtp.2019.020.02.5

Cited by 7 publications

(9 citation statements)

References 20 publications

(48 reference statements)

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“…Rohim dkk, (2019) melaporkan Fukoidan termasuk kelas polisakarida sulfasi yang banyak ditemukan pada alga cokelat, khususnya Sargassum sp. Potensi penghambatan enzim cyclooxygenase 1 dan 2 oleh fukoidan lebih baik dibandingkan aspirin (obat non-steroidal antiinflamasi) dan alginat, sehingga potensial sebagai antiinflamasi (Rohim et al, 2019).…”

Section: Journal Of Holistic Nursing and Health Scienceunclassified

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Dampak dan Terapi Non-Farmakologis Periodontitis pada Ibu Hamil; Kajian Literatur

Apriani¹,

Sunarjo

Widyawati

et al. 2022

Holistic Nursing and Health Science

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Introduction: According to WHO, periodontitis is a disease that affects about 20-50% of the world’s population. Periodontitis in pregnancy is often associated with poor pregnancy outcomes. Nowadays, periodontitis therapy is still giving antibiotics and mouth rinses (chlorhexidine) to reduce the dental plaque. However, these therapies have side effects in the form of antibiotic resistance, allergies and mouth irritation. Therefore, a non-conventional therapeutic that is more effective and safe is needed. Brown seaweed (Sargassum sp) is a promising alternative to its natural potential compounds as periodontitis therapy. The purpose of this study was to analyze the effect of Sargassum sp and the impact of periodontitis on pregnancy. Methods: This research is a systematic literature review by searching literature through various databases on; PubMed, Cochrane, ScienceDirect, and Google Scholar. The literature was examined in the span of 2015 to 2020. The criteria and keywords were; Sargassum and Periodontitis; Periodontitis and Pregnancy; Periodontal Disease and Pregnancy. Results: The results of this review found 12 articles that showed that periodontitis is one of the risk factors in pregnancy such as; preeclampsia, LBW, and premature. Furthermore, 9 other articles discussed the antibacterial and anti-inflammatory activity contained in Sargassum sp, which can inhibit the development of P.gingivalis and its virulence factors. Conclusion: The conclusion is metabolites of Sargassum sp “alginate” were able overcomed periodontitis in pregnancy. Thus, further research is expected to be able to intervene directly and analyze more broadly about the effect of Sargassum sp on periodontitis in pregnancy.

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Section: Journal Of Holistic Nursing and Health Scienceunclassified

“…Dengan demikian, senyawa-senyawa bioaktif dari Sargassum sp. dapat digunakan untuk terapi maupun pencegahan berbagai macam penyakit, termasuk penyakit periodontal pada wanita hamil (Rohim et al, 2019).…”

Section: Journal Of Holistic Nursing and Health Scienceunclassified

Dampak dan Terapi Non-Farmakologis Periodontitis pada Ibu Hamil; Kajian Literatur

Apriani¹,

Sunarjo

Widyawati

et al. 2022

Holistic Nursing and Health Science

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“…Red algae (Rhodophyta) have bioactive compounds, namely flavonoids, phenol hydroquinone, and triterpenoids [2]. Phlorotanin, fucoxanthin, fucoidan, alginate, and fucosterol are the dominant bioactive compounds in brown algae (Phaeophyta) [3]. While green algae (Chlorophyta) have alkaloid, saponin, flavonoid, tannin, and triterpenoid [4].…”

Section: Introductionmentioning

confidence: 99%

Bioactive Compounds and Antioxidant Activity of Tropical Red Algae Gracilaria sp. from Bintan Island, Indonesia

Hidayati

Karlina

Ningsih

et al. 2023

IOP Conf. Ser.: Earth Environ. Sci.

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Macroalgae that grow in the tropics are continuously exposed to ultraviolet radiation and sunlight. Macroalgae have self-defense to avoid damage caused by ultraviolet radiation by carrying out secondary metabolism and producing several bioactive compounds. The bioactive compounds produced have the potential to be utilized to inhibit free radicals that can cause degenerative diseases in humans. This research aims to identify bioactive compounds and determine the antioxidant activity, total phenolic compound, total flavonoid compound, and pigment content of red algae Gracilaria sp. from Bintan island. This research has the novelty of the sampling location to be later developed into a sustainable resource in the pharmaceutical field. Gracilaria sp. found in Bintan island was taken, dried in indirect sunlight, and macerated using universal solvent methanol. Phytochemical testing was conducted to determine the presence of flavonoids, steroids, triterpenoids, saponins, and tannins. Antioxidant activity was determined using DPPH as a free radical at the maximum wavelength of DPPH (515 nm) with an incubation time of 55 minutes. Total phenolic and flavonoid compounds were determined using standard solutions of gallic acid and quercetin, respectively. The results showed that the methanol extract of Gracilaria sp. contains flavonoid and tannin compounds, has a chlorophyll-a content of 0.43 mg/g, a carotenoid content of 0.91 µmol/g, the total phenolic compound of 4.67 mg/GAE g, total flavonoid compound of 2.26 mg/QE g and has antioxidant activity with IC50 value of 982.25 ppm. Utilization of Gracilaria sp extract from Bintan waters as a pharmaceutical ingredient is expected to increase prospects and sustainable use in the pharmaceutical and health fields.

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“…Extracts from brown seaweed contain phenols including eckol, phlorotannin, gallic acid, catechins, epicatechin, and phlorotannin [2]. Brown seaweed has bioactive compounds such as polyphenolics, terpenoids, polysaccharides, carotenoids, phenolic acids, chlorophyll, steroids, and glycolipids [3]. Seaweed extraction results show phytochemical components in the form of alkaloid compounds, flavonoids, phenols, and tannins [4].…”

Section: Introductionmentioning

confidence: 99%

“…The biological activity of seaweed bioactive compounds is antioxidant, anticancer, antitumor, anti-inflammatory, antihypertensive, anti-obesity, antidiabetic, antibacterial, antifungal, antiviral, antiallergic (ovalbumin and shrimp), hypocholesterolemia, neuroprotective, skin lightening and intracellular ROS protection [3]. In addition to containing many bioactive substances, seaweed also has antioxidants.…”

Section: Introductionmentioning

confidence: 99%

Effect of Ethanol Solvents in the Extraction Process of Bioactive Compounds from Brown Seaweed (Sargassum sp.) with the Ultrasound Assisted Extraction Method

et al. 2022

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Sargassum sp., part of brown algae, is traditionally used as animal feed. Nonetheless, Sargassum contains phenolic compounds that promise to be the raw material of natural antioxidants. The work is to extract phenolic compounds from Sargassum sp. in ethanol and to investigate the effect of the process on phenol yields. Several dried Sargassum sp. are milled in a certain size and extraction using ultrasound assisted extraction with ethanol solvent. Process variables are the extraction time (30-50 minutes) and the Ratio of Sargassum sp. to ethanol which is 5:100-15:100 (b/v), and power of 170-190 watts. Phenol compounds are quantified using the error acid method. The DPPH method is performed to check the antioxidant activity. To investigate the influence of the process, surface response methods based on central composite designs are applied in this work. 153.334 mgGAE/g in 30-minute extraction conditions, 170 watts of power, and a ratio between masses and solvents of 0.05. The antioxidant activity (IC50) of Sargassum sp. extract is 87.57 ppm.

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Senyawa-Senyawa Bioaktif Pada Rumput Laut Cokelat Sargassum Sp. : Ulasan Ilmiah

Cited by 7 publications

References 20 publications

Dampak dan Terapi Non-Farmakologis Periodontitis pada Ibu Hamil; Kajian Literatur

Dampak dan Terapi Non-Farmakologis Periodontitis pada Ibu Hamil; Kajian Literatur

Bioactive Compounds and Antioxidant Activity of Tropical Red Algae Gracilaria sp. from Bintan Island, Indonesia

Effect of Ethanol Solvents in the Extraction Process of Bioactive Compounds from Brown Seaweed (Sargassum sp.) with the Ultrasound Assisted Extraction Method

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