School reopening and risks accelerating the COVID-19 pandemic: A systematic review and meta-analysis protocol

Abstract

Background One of the most recent concerns of this pandemic regards the role of schools reopening in disease transmission, as well as the impact of keeping schools closed. While school reopening seems critical for the education and mental health of children, adolescents, and adults, so far the literature has not systematically reached a consensus whether to recommend the return to schools in a way that would be safe for students and staff. Objective To synthesize and critically evaluate the scientific evidence on the potential risk of accelerating the Coronavirus Disease 2019 (COVID-19) pandemic among children, adolescents, young adults, and adults with school reopening. Methods This systematic review and meta-analysis protocol was elaborated following the PRISMA-P. We will include all observational study designs, which report on the potential risk of accelerating the COVID-2019 pandemic with school reopening. Electronic databases included were MEDLINE/PubMed, Cochrane Library, EMBASE, Web of Science, SCOPUS and CNKI. Additional sources will be also retrieved, including Clinical trials.gov-NIH, The British Library, Pro Quest Dissertations Database, Public Health Gray Literature Sources and Health Evidence, Google Scholar, and pre-prints [medRXiv]. No restriction to language or date will be used as search strategy. In an independently manner, two investigators will select studies, perform data extraction, as well as perform a critical appraisal of the risk of bias and overall quality of the selected observational studies, based on their designs. The heterogeneity among the studies will be assessed using the I2 statistic test. According to the results of this test, we will verify whether a meta-analysis is feasible. If feasibility is confirmed, a random-effect model analysis will be carried out. For data analysis, the calculation of the pooled effect estimates will consider a 95% CI and alpha will be set in 0.05 using the R statistical software, v.4.0.4. In addition, we will rate the certainty of evidence based on Cochrane methods and in accordance with the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Expected results This systematic review and meta-analysis will provide better insights into safety in the return to school in the context of the COVID-2019 pandemic, at a time when vaccination advances unevenly in several countries around the world. Hence, consistent data and robust evidence will be provided to help decision-makers and stakeholders in the current pandemic scenario. PROSPERO registration number CRD42021265283; https://clinicaltrials.gov.

Analysis of Survival of Patients Hospitalized with COVID-19 in Espírito Santo, Brazil

“…The findings of the current study showed that chronic cardiovascular disease, including hypertension, is a factor associated with a higher risk for death and a shorter survival among hospitalized patients, thus corroborating the literature [ 25 ]. The impact of COVID-19 on the cardiovascular system is worth noting, as individuals with pre-existing disease are among the most affected by the disease and have a more severe clinical course [ 24 , 25 , 26 , 27 , 28 , 29 , 30 ].…”

Essential core competencies for scope of practice of paediatric oncology nurses in Latin America: a scoping review protocol

“…Initially, we will identify the existence of an index of specific subject titles in each database (such as MeSH terms , CINAHL Headings , Entree terms and the DeCS) and their synonyms (keywords). Subsequently, the search terms were combined using the Boolean operators ‘AND’ and ‘OR’ 35–37. The search strategy that combines the controlled descriptors and keywords used in each database is depicted on the online supplemental file 1.…”

“…Subsequently, the search terms were combined using the Boolean operators 'AND' and 'OR'. [35][36][37] The search strategy that combines the controlled descriptors and keywords used in each database is depicted on the online supplemental file 1.…”

Palliative care in the treatment of women with breast cancer: a scoping review protocol

“…Initially, we will identify the existence of an index of specific subject in each database (with MeSH terms, Emtree, DeCS, and CINAHL headings) and their synonyms (keywords). The search terms will then be combined using the Boolean operators “AND” and “OR” [29,30].…”

“…The data will be extracted through a form designed by a research team member adapted to the data extraction template proposed by the JBI and considering previously published extraction forms [29,33-36]. The information to be extracted includes a) study identification and objectives; b) study population and baseline characteristics; c) study design; d) sample size; e) results; f) main findings; g) clinical and epidemiological significance; h) conclusions, i) implications, and j) limitations.…”