Satellite association and translocation mongolism.

DNA replication studies of human D-group chromosomes in satellite associations

“…In at least two studies, families with chromosomally abnormal individuals have been shown to have an increased incidence of satellite association Zellweger et al, 1966). The incidence of satellite associations (F roland and M ikkelsen, 1964;Cohen and Shaw, 1967), types and frequency distributions of G and D chromosomes in associations (van B rink et al, 1962;Cohen and Shaw, 1967) variations among individuals (Engmann, 1967;Ford and W oollam, 1967) have now been studied.…”

Chromosomal Satellite Association in Women Using Oral Contraceptives and their Progeny

“…The frequencies with which the acrocentric chromosomes occur in dividing cells of normal subjects vary, (Froland 1964, Reitalu 1964, and Bishun 1966) the significance of which has recently been reviewed by Zellweger et al (1966). The latter postulated that an increased frequency of D and G chromosome associations tends to render the progeny of the individuals more susceptible to D/G and G/G translocations.…”

Assessment of Cytotoxicity and Genotoxicity in Patients with Rheumatoid Arthritis and its Relation to Disease Activity and Medications

“…33 . Lezhava et al 34 have mentioned that the associations of human acrocentric chromosomes account for elevated incidence of chromosome rearrangements and consequently, can cause chromosomal disorders.…”

“…Lezhava et al 34 have mentioned that the associations of human acrocentric chromosomes account for elevated incidence of chromosome rearrangements and consequently, can cause chromosomal disorders. The normal range of Sat Ass established by examining 1161 metaphase plates of 22 controls ranged from 2-27% with a mean of 13.3% 33 . In the present study, the mean of Sat Ass in the control group was 6.2±6.49, in RA patients was 38.16±14.77.…”