Saliva and the Control of Its Secretion

Ekström, Jørgen; Khosravani, Nina; Castagnola, Massimo; Messana, Irene

doi:10.1007/174_2011_481

Cited by 61 publications

(105 citation statements)

References 138 publications

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“…The autonomic innervation of the parotid gland is performed mainly by the glossopharyngeal nerve. Nevertheless, there is evidence that facial nerve, that runs through the gland parenchyma, provides cholinergic innervation to the gland secretory cells participating in the salivary secretion . The amylase is the most abundant salivary protein and approximately 80% of this protein is produced by the parotid gland.…”

Section: Introductionsupporting

confidence: 84%

Salivary parameters and oral health in the Moebius syndrome

Mussi

Moffa

Castro

et al. 2016

Special Care in Dentistry

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Section: Introductionsupporting

confidence: 84%

Salivary parameters and oral health in the Moebius syndrome

Mussi

Moffa

Castro

et al. 2016

Special Care in Dentistry

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“…The development of the latter is explained by the occurrence of perivascular swelling being observed at the sub-microscopic level. It should be mentioned that the excretory ducts are characterized by low water permeability [29]. Thus, detected dystrophic changes, probably, lead to the alterations in electrolyte composition of secondary saliva [3,15].…”

Section: Resultsmentioning

confidence: 99%

Effect of Hyperglycemia on the Excretory Ducts of the Submandibular Gland (Histologic Study)

et al. 2016

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The paper highlights the peculiarities of histological changes in different subdivisions of the intralobular duct of the submandibular gland in rats in case of experimental hyperglycemia. Materials and methods. The study included 40 male Wistar rats weighing 230 to 250g. Experimental hyperglycemia was induced by a single intraperitoneal administration of streptozotocin. Biochemical and morphological investigations were conducted; the morphometric analysis was carried out. Results. Since the 28th day of the experiment, on the background of dynamic increase in the levels of glucose and glycated hemoglobin in the blood, there was observed the development of dystrophic changes in epithelial cells of the granular and striated ducts being accompanied by a gradual decrease in epithelial cell height by 10.28 -29.46% and 10.77 -28.28%, respectively. Morphological changes in the intercalated ducts were detected later -since the 42 nd day of the experiment and the decrease in their epithelial cell height -by 15.60%, was seen on the 70 th day only. Conclusions. Morphological changes in different subdivisions of the intralobular duct are of dystrophic nature and can be histologically detected since the 28 th day of the experiment; they depend on the duration of hyperglycemia and are accompanied by a dynamic decrease in epithelial cell height.

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“…96 Individuals with hyposalivation are more susceptible to dental caries because of the loss of the many protective factors in saliva. 7,97 The reduced flow rate retards oral sugar clearance and also adversely affects salivary buffering of plaque acid. At a low flow rate the salivary bicarbonate concentration is reduced, causing a fall in salivary pH, and although the phosphate concentration is increased at a low flow rate, its effectiveness as a buffer is reduced since the salivary pH will be less than the pK 2 value for phosphate (see Eq.…”

Section: Salivary Inorganic Components Erosion and Dental Cariesmentioning

confidence: 99%

“…1,2 In addition there have been several papers which have summarised a number of functions of saliva. [3][4][5][6][7][8] The World Workshop on Oral Medicine VI was held in Orlando, Florida, in April 2014, and one Group was asked to carry out a review of medication-induced salivary gland dysfunction. This was to include an updated and comprehensive assessment of the functions of saliva, since there have been several recent advances in our understanding of the role of saliva in oral health.…”

Section: Introductionmentioning

confidence: 99%