Roles and applications of probiotic Lactobacillus strains

Zhang, Zhongwang; Lv, Jing; Pan, Li; Zhang, Yongguang

doi:10.1007/s00253-018-9217-9

Cited by 160 publications

(97 citation statements)

References 84 publications

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“…Some of the reported beneficial effects of probiotics in human health include anticancer [99][100][101][102][103][104][105][106][107][108][109][110][111], anti-allergic [112,113], anti-diabetic [114][115][116], anti-obesity [117][118][119][120], anti-pathogenic [121,122], immunomodulatory [123], and anti-inflammatory [124][125][126][127] activities [128], as reported in Table 1.…”

Section: Health Promoting Effect Of Prebiotics Probiotics and Synbimentioning

confidence: 99%

An Updated Overview on Nanonutraceuticals: Focus on Nanoprebiotics and Nanoprobiotics

Durazzo

Nazhand

Lucarini

et al. 2020

IJMS

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Over the last few years, the application of nanotechnology to nutraceuticals has been rapidly growing due to its ability to enhance the bioavailability of the loaded active ingredients, resulting in improved therapeutic/nutraceutical outcomes. The focus of this work is nanoprebiotics and nanoprobiotics, terms which stand for the loading of a set of compounds (e.g., prebiotics, probiotics, and synbiotics) in nanoparticles that work as absorption enhancers in the gastrointestinal tract. In this manuscript, the main features of prebiotics and probiotics are highlighted, together with the discussion of emerging applications of nanotechnologies in their formulation. Current research strategies are also discussed, in particular the promising use of nanofibers for the delivery of probiotics. Synbiotic-based nanoparticles represent an innovative trend within this area of interest. As only few experimental studies on nanoprebiotics and nanoprobiotics are available in the scientific literature, research on this prominent field is needed, covering effectiveness, bioavailability, and safety aspects.

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Section: Health Promoting Effect Of Prebiotics Probiotics and Synbimentioning

confidence: 99%

An Updated Overview on Nanonutraceuticals: Focus on Nanoprebiotics and Nanoprobiotics

Durazzo

Nazhand

Lucarini

et al. 2020

IJMS

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“…48 In another study, 3-phenyllactic acid is thought to display antimicrobial properties and to be associated with phenylalanine metabolism. 49 In addition, the occurrence of 3-phenylpropionic acid is associated with microbially transformed plant polyphenols such as flavanols, flavanones and tannins. 50 Putrescin is a polyamine produced by the breakdown of amino acids and mainly produced by the microbiota.…”

Section: The Fecal Metabolome and Lipidomementioning

confidence: 99%

“…They can derive from food, the microbiota converting food constituents, or they can be primary bacterial or host metabolites. According to the literature, Phenyl lactic acids are mostly associated with lactic acid bacteria and they have antifungal and antimicrobial properties 49 . Additionally, with a focus on integration with metagenomic analysis, the high variability seen in these ten healthy subjects is probably due to variations in both food intake and in microbiota composition 57 .…”

Section: Correlation Between Fecal Lipids and Polar Metabolitesmentioning

confidence: 99%

Describing the fecal metabolome in cryogenically collected samples from healthy participants

Trošt

Ahonen

Suvitaival

et al. 2019

Preprint

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Introduction:The chemical composition of feces plays an important role in human metabolism. Metabolomics and lipidomics are valuable tools for screening the metabolite composition in feces. Here we set out to describe fecal metabolite composition in healthy participants in frozen stools.Methods: Frozen stool samples were collected from 10 healthy volunteers and cryogenically drilled in four areas along the specimen. Polar metabolites were analyzed using derivatization followed by two-dimensional gas chromatography and time of flight mass spectrometry. Lipids were detected using ultra highperformance liquid chromatography coupled with quadruple time-of-flight mass spectrometry. The technical variation threshold was set to 30% in pooled quality control samples and metabolite variation was then assessed in four areas per specimen. A data-generated network using metabolites found in all areas was computed for healthy participants.Results: 2326 metabolic features were detected. Out of a total of 298 metabolites that were annotated we report here 185 that showed a technical variation of x< 30%. These metabolites included amino acids, fatty acid derivatives, carboxylic acids and phenolic compounds. Lipids predominantly belonged to the groups of diacylglycerols, triacylglycerols and ceramides. Metabolites varied between sampling areas (14%-80%). A network using metabolites present in all areas showed two main clusters, DAG lipids and phenyllactic acid. Conclusions:In feces from healthy participants, the main groups detected were phenolic compounds, ceramides, diacylglycerols and triacylglycerols. Metabolite levels differed considerably depending on the sampling area.

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“…Probiotics are living micro‐organisms that provide a potential alternative strategy to antibiotics, as they are useful in maintaining gut microbial balance by reducing the pathogenic microbes and thereby improve host health (Yadav and Shukla ). Specifically, the micro‐organisms most frequently used as probiotic agents are Lactobacillus , which are the major component of gastrointestinal flora (Zhang et al ). Some strains of Lactobacillus , such as L. plantarum , L. reuteri , and L. gasseri , have been recently identified from piglet gastrointestinal tract, which are reported as one of the most promising probiotics on account of their beneficial effects on gastrointestinal health and growth in weaned piglets (Hu et al ; Xin et al ; Wang et al ).…”

Section: Introductionmentioning

confidence: 99%

Isolation of swine‐derived Lactobacillus plantarum and its synergistic antimicrobial and health‐promoting properties with ZnO nanoparticles

Zheng

et al. 2020

J Appl Microbiol

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Aims The purpose of this study was to isolate Lactobacillus from gastrointestinal tract of healthy postweaning piglets and investigate its synergistic antimicrobial and probiotic effects with ZnO nanoparticles (nZnO). Methods and Results Of the 128 isolates, Lactobacillus plantarum BLPL03 was selected based on its excellent acid and bile salt tolerance properties. Lactobacillus plantarum BLPL03 was sensitive to β‐lactams, macrolides, amphenicols and cephalosporins, whereas it displayed the steady resistance to aminoglycosides, tetracyclines, quinolones and peptide antibiotics. In vitro analysis of antibacterial activities showed that L. plantarum BLPL03 inhibited the four common food‐borne pathogenic bacteria including Escherichia coli O157:H7 CMCC 44828, Salmonella Typhimurium ATCC 13311, Staphylococcus aureus CMCC 26003 and Listeria monocytogenes CMCC 54007 in synergy with nZnO. Furthermore, the quantitative polymerase chain reaction test demonstrated that the combined administration of L. plantarum BLPL03 fermentation liquor (LFL) and nZnO synergistically elevated the faecal number of Bifidobacterium by 73·19‐fold, and reduced the two potential enteropathogenic bacteria Enterobacteriaceae and Clostridium perfringens in mice challenged with Salm. Typhimurium. Finally, dietary supplementation with low dose of nZnO (20 mg kg−1) when combined with LFL administration enhanced final body weight, fur appearance and average daily gain, and decreased feed conversion ratio and diarrhoea incidence in weaned piglets. The faecal Bifidobacterium and Lactobacillus of piglets were dramatically enhanced by 81·96‐ and 3·15‐fold, respectively, after administration of a mixture of nZnO and LFL. Meanwhile, combination of nZnO with LFL resulted in low levels of Bacteroides, Enterococcus, and Enterobacteriaceae. Conclusions A combination of nZnO and LFL exhibits potential health‐benefit properties for the control of gut microbial composition by their synergistic antimicrobial and probiotic effects. Significance and Impact of the Study This study may provide a potential nutritional strategy to improve performance and gut health of animals with gut microbiota disorders caused by pathogen infections and weanling, and so on.

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Roles and applications of probiotic Lactobacillus strains

Cited by 160 publications

References 84 publications

An Updated Overview on Nanonutraceuticals: Focus on Nanoprebiotics and Nanoprobiotics

An Updated Overview on Nanonutraceuticals: Focus on Nanoprebiotics and Nanoprobiotics

Describing the fecal metabolome in cryogenically collected samples from healthy participants

Isolation of swine‐derived Lactobacillus plantarum and its synergistic antimicrobial and health‐promoting properties with ZnO nanoparticles

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