Robust nanocoatings based on ionic silicones

Puciul-Malinowska, Agnieszka; Zapotoczny, Szczepan

doi:10.1039/c8nr03090a

Cited by 5 publications

(6 citation statements)

References 51 publications

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“…The concept of the LbL technique was adapted for colloidal particles that serve as removable templates leading to the formation of the capsules with liquid cores [ 32 ]. Such a procedure enables the utilization of macromolecules of complex structure [ 34 ] varying in charge or glass transition [ 35 ] to reach the coatings and capsules of desired functionality [ 36 , 37 ].…”

Section: Fabrication Of Polymer Core-shell Nanocapsulesmentioning

confidence: 99%

Polymer Capsules with Hydrophobic Liquid Cores as Functional Nanocarriers

et al. 2020

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Recent developments in the fabrication of core-shell polymer nanocapsules, as well as their current and future applications, are reported here. Special attention is paid to the newly introduced surfactant-free fabrication method of aqueous dispersions of nanocapsules with hydrophobic liquid cores stabilized by amphiphilic copolymers. Various approaches to the efficient stabilization of such vehicles, tailoring their cores and shells for the fabrication of multifunctional, navigable nanocarriers and/or nanoreactors useful in various fields, are discussed. The emphasis is placed on biomedical applications of polymer nanocapsules, including the delivery of poorly soluble active compounds and contrast agents, as well as their use as theranostic platforms. Other methods of fabrication of polymer-based nanocapsules are briefly presented and compared in the context of their biomedical applications.

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Section: Fabrication Of Polymer Core-shell Nanocapsulesmentioning

confidence: 99%

Polymer Capsules with Hydrophobic Liquid Cores as Functional Nanocarriers

et al. 2020

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“…Zwitterionic groups such as sulfobetaines and carboxybetaines are commonly used due to their enhanced wettability caused by the polarity of the charged groups. 87−92 LbL coatings have been formed on silicones to modify surfaces properties, 93 with potential for superior stability versus grafted polymer chains. 94 LBL coatings are comprised of alternating layers held together by secondary forces.…”

Section: Surface Modificationsmentioning

confidence: 99%

Biomedical Silicones: Leveraging Additive Strategies to Propel Modern Utility

Marmo

Grunlan

2023

ACS Macro Lett.

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Silicones have a long history of use in biomedical devices, with unique properties stemming from the siloxane (Si–O–Si) backbone that feature a high degree of flexibility and chemical stability. However, surface, rheological, mechanical, and electrical properties of silicones can limit their utility. Successful modification of silicones to address these limitations could lead to superior and new biomedical devices. Toward improving such properties, recent additive strategies have been leveraged to modify biomedical silicones and are highlighted herein.

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“…PEMs obtained from two oppositely-charged derivatives of the same polymer have already been reported, both for synthetic polymers, e.g., silicones [ 32 ] or PAH [ 33 , 34 ] and a natural polymer, i.e., chitosan [ 29 , 35 ]. However, these studies included PEMs obtained using just one pair (two in one case [ 33 ]), so they did not allow drawing conclusions on the influence of polymer substitution on the PEM behavior.…”

Section: Introductionmentioning

confidence: 99%

Tuning the Surface Properties of Poly(Allylamine Hydrochloride)-Based Multilayer Films

et al. 2021

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The layer-by-layer (LbL) method of polyelectrolyte multilayer (PEM) fabrication is extremely versatile. It allows using a pair of any oppositely charged polyelectrolytes. Nevertheless, it may be difficult to ascribe a particular physicochemical property of the resulting PEM to a structural or chemical feature of a single component. A solution to this problem is based on the application of a polycation and a polyanion obtained by proper modification of the same parent polymer. Polyelectrolyte multilayers (PEMs) were prepared using the LbL technique from hydrophilic and amphiphilic derivatives of poly(allylamine hydrochloride) (PAH). PAH derivatives were obtained by the substitution of amine groups in PAH with sulfonate, ammonium, and hydrophobic groups. The PEMs were stable in 1 M NaCl and showed three different modes of thickness growth: exponential, mixed exponential-linear, and linear. Their surfaces ranged from very hydrophilic to hydrophobic. Root mean square (RMS) roughness was very variable and depended on the PEM composition, sample environment (dry, wet), and the polymer constituting the topmost layer. Atomic force microscopy (AFM) imaging of the surfaces showed very different morphologies of PEMs, including very smooth, porous, and structured PEMs with micellar aggregates. Thus, by proper choice of PAH derivatives, surfaces with different physicochemical features (growth type, thickness, charge, wettability, roughness, surface morphology) were obtained.

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Robust nanocoatings based on ionic silicones

Cited by 5 publications

References 51 publications

Polymer Capsules with Hydrophobic Liquid Cores as Functional Nanocarriers

Polymer Capsules with Hydrophobic Liquid Cores as Functional Nanocarriers

Biomedical Silicones: Leveraging Additive Strategies to Propel Modern Utility

Tuning the Surface Properties of Poly(Allylamine Hydrochloride)-Based Multilayer Films

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