Risk factors associated with the progression of COVID-19 in elderly diabetes patients

Abstract

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Risk Factors and Blood Pressure Control Targets Associated With the Clinical Outcome of Elderly COVID-19 Patients With Hypertension: a Retrospective Cohort Study

“…Our study provides the clinical characteristics of elderly concerning the role of comorbidities in the setting of COVID-19. Similar to the previously reported results, hypertension, diabetes, and cardiovascular diseases are the most frequent comorbidities (7,11,12). However, in our cohort, patients with hypertension reach 59.4% (79 of 133), 27.1% of total patients and 39.2% of the hypertension group have adverse clinical outcomes, which are higher than other studies (13).…”

“…In addition to blood pressure, the most effective factor in the progression of COVID-19 hypertension patients in this cohort was maximum BG value, which was out of our expectation. This may be because the maximum BG value presents the worst pancreatic conditions and makes infection di cult to control (11,22). (2) PT level was also an important risk factor for clinical outcome of elderly COVID-19 cases with hypertension, while D-dimer is not mentioned in our study.…”

“…Maximum blood pressure, minimum blood pressure, pulse pressure and mean arterial pressure were all extracted based from the above data. Diabetes, cardiac injury, acute liver injury, and acute kidney injury status were designated based on the patient's medical history and guideline for diagnosis (11).…”

Diabetes mellitus and COVID-19: Understanding the association in light of current evidence

“…Elevated glucose level in diabetic patients is considered an independent risk factor in the early effect of COVID-19[ 24 ]. Elevated glucose level associated with severe pancreatic problems can lead to worsening of the pancreatic condition.…”

Impacto do Diabetes Mellitus sobre o prognóstico da Covid-19

“…Entre estes, 40,4% desenvolveram a forma severa da doença, apresentando complicações associadas a um elevado risco de vida, seguido de contagens maiores de leucócitos e neutrófilos, e uma menor contagem de linfócitos, além de níveis aumentados de proteína C reativa, a qual foi diretamente ligada a incidência de eventos ruins durante o período de internação. A coexistência de DM também se mostrou como fator chave para o desenvolvimento de pneumonia grave, funcionamento anormal de órgãos e um maior risco de progressão da COVID-19 (Zhang et al, 2021).…”