Retinal Vasospasm During an Attack of Migraine

Killer, Hanspeter E.; Forrer, A.; Flammer, Josef

doi:10.1097/00006982-200304000-00023

Cited by 75 publications

(44 citation statements)

References 2 publications

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“…Additional studies led further support to the idea that some parallelisms in ocular and digital blood flow exist [11,15] and that the presumed ocular vasospastic syndrome is associated with a lack of blood flow autoregulation [12,14,18]. Ocular vasospastic phenomena have also been observed directly in patients with unstable primary angina [2] and with migraine [24]. Ocular vasospastic phenomena have been advocated to be a potential risk factor in various ocular conditions, including glaucoma [1], retinal venous occlusion [30], acute ischaemic optic neuropathy [23], and central serous chorioretinopathy [36].…”

Section: Discussionmentioning

confidence: 92%

“…More recent studies have demonstrated that retinal microvasculature may show abnormalities related to elevated concurrent blood pressure in older people [25,39,42] and to cardiovascular complications [6,26,27,38,40,41,43,44]. From a functional perspective, diseases with vascular dysregulation have been reported to induce vasospasms in the retinal vessels [2,17,24], and retinal blood flow abnormalities have been reported in otherwise healthy subjects with a propensity for systemic vascular dysregulation [13]. It has been suggested that such alterations may play a role in the pathogenesis of glaucoma [8,13] and also in other ocular diseases [9].…”

Section: Introductionmentioning

confidence: 99%

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Retinal vascular diameter in young subjects with a vasospastic propensity

Branca

Orgül

Zawinka

et al. 2005

Graefe's Arch Clin Exp Ophthalmo

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Section: Discussionmentioning

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Retinal vascular diameter in young subjects with a vasospastic propensity

Branca

Orgül

Zawinka

et al. 2005

Graefe's Arch Clin Exp Ophthalmo

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“…Successful treatment with 500 mg of acetazolamide and 0.8 mg of sublingual nitroglycerine for vasospasm has been reported [66], consistent with possible association with low-pressure glaucoma and the nitric oxide theory of pathogenesis. Reports of successful steroid use to abort migraine also exist in the literature [13,32].…”

Section: Other Medicationsmentioning

confidence: 56%

Retinal, ophthalmic, or ocular migraine

Pradhan¹,

Chung

2004

Curr Neurol Neurosci Rep

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Ocular migraine, an uncommon cause of transient monocular visual loss, is an entity physicians should be able to recognize in order to provide appropriate treatment and to avoid unnecessary testing. The following text provides an overview of ocular migraine, including discussion of accepted terminology, clinical presentation, and pathophysiology. An ocular and systemic differential diagnosis, appropriate evaluation, therapy, and prognosis are also discussed.

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“…The evaluation of the eye blood supply of patients during migraine attacks is challenging. Killer et al [35] found that the temporal artery blood flow decreased in migraine headache when the patient had a defect in the left eye vision. Other studies have demonstrated that the central retinal artery and posterior ciliary artery blood flows were more reduced during migraine attacks in patients with migraine without aura compared to healthy controls [36].…”

Section: Discussionmentioning

confidence: 99%

Altered Retinal Nerve Fiber Layer Thickness and Choroid Thickness in Patients with Migraine

Wang

Yang

et al. 2018

Eur Neurol

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Background: Migraine is a chronic neurological disorder. However, its pathogenesis is still unclear. This study aimed to measure the posterior ocular structure in patients with migraine using enhanced depth imaging (EDI)-optical coherence tomography (OCT) and explore the probable pathogenesis of migraine. Methods: A total of 115 patients diagnosed with migraine and 50 healthy volunteers were recruited. These participants underwent an ocular examination to exclude the ocular diseases. Retinal nerve fiber layer thickness, macular thickness, and choroid thickness were assessed using EDI-OCT. Results: The nasal peripapillary retinal nerve fiber layer (pRNFL) was significantly thinner in the migraine with aura group (p = 0.001) than that in the control group. The inferior inner macular layer was thinner in the migraine with aura group (p = 0.005). The 3 subfields of choroid were significantly thinner in the migraine with aura group (p = 0.044, 0.008, and 0.029). However, there was no difference between the migraine without aura group and the control group. The nasal pRNFL in migraine with aura was negatively correlated with the product of duration (months) and number of attacks/month (p = 0.039). Conclusion: The changes in the ocular posterior structure may serve as evidence of the trigeminovascular system mechanism underlying migraine and transneuronal retrograde degeneration of the primary visual cortex, which reflects the cortical spreading depression.

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Retinal Vasospasm During an Attack of Migraine

Cited by 75 publications

References 2 publications

Retinal vascular diameter in young subjects with a vasospastic propensity

Retinal vascular diameter in young subjects with a vasospastic propensity

Retinal, ophthalmic, or ocular migraine

Altered Retinal Nerve Fiber Layer Thickness and Choroid Thickness in Patients with Migraine

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