Resistin concentration is inversely associated with objectively measured physical activity in healthy older women

Regulation of cardiovascular health and disease by visceral adipose tissue‐derived metabolic hormones

“…Serum concentrations of inflammatory adipocytokines, such as leptin and resistin, increase with age and are positively correlated with the accumulation and redistribution of adipose tissue, vascular inflammation and adversely affect cardiac performance and vascular health (Fantin et al., 2020; Unger, 2005; Xu et al., 2020). In older adults, higher concentrations of leptin and resistin are associated with greater risk of physical frailty, health deterioration and reduced chances of an organism's survival (Gencer et al., 2016; Lana et al., 2016; Rava et al., 2020). Older patients with severe aortic valve disease have higher plasma resistin levels, which are associated with increased inflammatory macrophage content and a degree of valvular calcification (Mohty et al., 2010; Sweeney et al., 2021).…”