Resistência à mupirocina entre isolados de Staphylococcus aureus de profissionais de enfermagem

Abstract

RESUMO ABSTRACT Objectives:To assess colonization by Staphylococcus aureus sensitive and resistant to methicillin found in the saliva of nurses and, to recognize the mupirocin profile of resistance. Methods: It was collected three saliva samples of 356 (94.2%) professional research participants, totaling 1068 samples processed. All ethical aspects were covered. Microbiological analysis included the phenotypic identification, according to the standards of the Clinical and Laboratory Standards Institute. Results: In the first collection were obtained 73 individuals colonized by Staphylococcus aureus, 48 in the second and 37 in the third, totaling 158 samples of Staphylococcus aureus. Of these, 24 (15.2%) were resistant to oxacillin and 30 resistant to mupirocin (18.9%). Mupirocin resistance was observed sharply in the Staphylococcus aureus resistant to methicillin (MRSA); of 24 MRSA, 17 (70.8%) were resistant to this antibiotic. Conclusion: The results indicated that mupirocin resistance is a major problem since this antibiotic is an excellent ally in the measures taken to control infection in health services. Keywords: Staphylococcus aureus; Drug resistance, multiple; Mupirocin ; Nursing team RESUMEN Objetivos: Evaluar la colonización por Staphylococcus aureus sensibles y resistentes al meticilín en la saliva de profesionales de enfermería y, reconocer el perfil de resistencia a la mupirocina. Métodos: Fueron recolectadas tres muestras de saliva de 356 (94,2%) profesionales participantes de la investigación, totalizando 1.068 muestras procesadas. Todos los aspectos éticos fueron contemplados. El análisis microbiológico comprendió la identificación fenotípica, según normas del Clinical and Laboratory Standards Institute. Resultados: Fueron obtenidos 73 individuos colonizados por Staphylococcus aureus en la primera recolección, 48 en la segunda y 37 en la tercera, sumando 158 muestras aisladas de Staphylococcus aureus. De esas, 24 (15,2%) eran resistentes a la oxacilina y 30 resistentes a al mupirocina (18,9%). La resistencia al mupirocina fue observada de forma pronunciada en los Staphylococcus aureus resistentes a la metacilina (MRSA); de los 24 MRSA, 17 (70,8%) se presentaron resistentes a este antimicrobiano. Conclusión: Los resultados indicaron que la resistencia a la mupirocina es un importante problema, ya que ese antibiótico es un excelente aliado en las medidas de control de las infecciones de servicios de salud.

Staphylococcus Aureus in Nursing Professionals and the Microorganism’s Susceptibility Profile to Antimicrobials

“…[2][3][4][5][6][7][8][9] Asymptomatic carriers of Staphylococcus aureus may act as disseminators of the microorganism to a population susceptible to colonization. 10 Approximately 20% of the population may be considered persistent carriers, 60% transitory carriers, and the remaining 20% do not present colonization by Staphylococcus aureus.…”

Virulence Factors in Methicillin-Resistant <i>Staphylococcus aureus</i> Isolated from ICU Units in Brazil

“…In the United States there is about 94,000 individuals infected with MRSA and about 18% result in death. Most invasive MRSA infections (86%) occurred in individuals with previous exposure to a hospital environment or the health care service [20].…”

Colonização bacteriana e resistência antimicrobiana em trabalhadores de saúde: revisão integrativa

“…In various studies on healthcare workers, scientific evidence has shown the presence of methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus ssp, Enterococcus faecalis, Acinetobacter baumannii, Streptococcus ssp and Serratia ssp, colonizing the nasal cavity, white coats and saliva of hospital workers. (2)(3)(4) Direct contact between health workers and infected patients can propagate the contamination of these superbugs, which increases the possibility of professionals acquiring resistance to available antimicrobials for treating diseases. (2) To prevent this risk, individual and collective protection measures need to be adopted.…”

“…(2)(3)(4) Direct contact between health workers and infected patients can propagate the contamination of these superbugs, which increases the possibility of professionals acquiring resistance to available antimicrobials for treating diseases. (2) To prevent this risk, individual and collective protection measures need to be adopted. Workers should use personal protective equipment (PPE) that is appropriate for the type of work being performed and under adequate working conditions.…”