2014
DOI: 10.4236/aim.2014.44027
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Virulence Factors in Methicillin-Resistant <i>Staphylococcus aureus</i> Isolated from ICU Units in Brazil

Abstract: Species of Staphylococcus are common in hospital infection (HI). Methicillin resistant S. aureus(MRSA) has also become a serious problem in Brazilian HI. The aim of this study was to characterize the pathogenicity of methicillin-resistant S. aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) isolated in public hospitals. The clinical isolates were obtained from intensive care unit. The MRSA and MSSA strains were genotyped by PCR for detection genes related to virulence factors. Moreover, the … Show more

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Cited by 6 publications
(13 citation statements)
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“…2,8,20 In Brazil, the investigators were able to detect sea (3.23%) and seb (54.84%) genes, respectively, but failed to detect the sec gene. 3 In this study, the occurrence of eta and tst genes was 5.2 and 10.5%, respectively. Previous studies have found wide variation (0.2% to 94.4%) in the occurrence of the eta gene in Staphylococcus aureus.…”
Section: Discussionmentioning
confidence: 46%
“…2,8,20 In Brazil, the investigators were able to detect sea (3.23%) and seb (54.84%) genes, respectively, but failed to detect the sec gene. 3 In this study, the occurrence of eta and tst genes was 5.2 and 10.5%, respectively. Previous studies have found wide variation (0.2% to 94.4%) in the occurrence of the eta gene in Staphylococcus aureus.…”
Section: Discussionmentioning
confidence: 46%
“…Preview studies have shown that MRSA strains have more virulence genes than MSSA strains, which can explain the higher intensity of the inflammatory response developed by the MRSA strain (Lim, Yeo, Suhaili, & Thong, 2012). Moreover, the MRSA strain studied in this paper was analyzed and its virulence factors were identified as Spa, PVL and Sea genes as well as it is a strong producer of biofilm (Souza et al, 2014). Figure 1.…”
Section: Resultsmentioning
confidence: 98%
“…14 (1.45%), as well as we were not identified (no growth) 797 (82.67%) ( Fig. 2 and Table 3) [17][18][19].…”
Section: Total Bacterial Count Of Indoor and Outdoor Patientsmentioning
confidence: 92%
“…Science 1960s, S. aureus initially described, on the other hand, S. aureus, is principally amalgamated with skin, skin glands and mucous membrane of warmblooded animals so an adaptable microbe as well as a frequent invader of animals, and humans [3]. The organism is favour nosocomial bacteria implicate with several infections, including pneumonia, septic arthritis, osteomyelitis, endocarditis, toxic-shock syndrome and food poisoning [4][5][6][7]. Many scientists are of the opinion that, (healthcare associated methicillinresistant S. aureus, HA-MRSA), the burden of MRSA colonisation and infection has recently enlarged to further ecological slot [8].…”
Section: Introductionmentioning
confidence: 99%