Renal Involvement in Snakebite

Further Observations of Renal Insufficiency in Snakebite

“…The interstitial lesions consisted of edema and cellular infil trations. The findings were in accord with those observed in the previous reports [1,2,4,8]. Although glomerulonephritis and nephrotic syndrome have been described in man [11,12], this has not been our experience [2], In these two cases the glomerular changes in general were not remarkable except for mild mesangial proliferation.…”

“…Venous changes evidenced by necrosis of the wall and luminal occlusion by platelet thrombus were also noted. Since arteritis was present at the level of interlobular and arcuate arteris, the lesions could have been missed in the previous observations [2], No artery was seen in those sections. Arteritis persisted, although milder in degree, 4-6 weeks later.…”

“…Glomerulonephritis and nephrotic synsdrome are occasionally observed [11,12]. Renal infarct has been described [13], In our previous reports acute tubular necrosis with renal failure has been shown in patients bitten by seasnakes and Russell's vipers [1,2]. Further renal histological study in two additional patients with immuno fluorescent techniques forms the basis of this presentation.…”

“…Renal involve ment in man is usually in the form of acute renal failure secondary either to the tubular necrosis or cortical necrosis [1][2][3][4][5][6][7][8][9][10]. Glomerulonephritis and nephrotic synsdrome are occasionally observed [11,12].…”

Snakebite nephropathy (Review Article)

“…The incidence of proteinuria in snakebite is variable depending on the kind of snakes involved and there is also geographical variation. In a series of 400 tropical snakebite patients proteinuria was observed in 4% 16 . The magnitude of proteinuria is less than 500 mg/24 h, and this is usually a transient finding which completely resolves when the patient recovers.…”