Relationship between cognitive function and regional cerebral blood flow in different types of dementia

Abstract

Close coupling was evident between reduced rCBF and cognitive dysfunction in patients with dementia. Use of neuropsychologic tests and rCBF determinations in combination should enhance diagnostic accuracy.

Frontal dysfunctions of ALS-PBP patients in relation to their bulbar symptoms and rCBF decline

“…Accumulation of transactivation responsive region (TAR) DNA-binding protein of 43 kDa (TDP-43) in most cases of ALS and an FTD subtype (frontotemporal lobar degeneration with ubiquitinated inclusions) provided clear evidence of the close relationship between these two disorders, as well as identification of FUS as the novel pathological protein in both disorders [29]. Relationships between cognitive impairment and rCBF have been identified in different types of dementia such as Alzheimer's disease (AD), FTD and ALS [30,31]. In the present study, we investigated rCBF using the latest easy Z-score imaging system (eZIS) ver.…”

Three-dimensional stereotactic ROI template for measuring regional cerebral blood flow in 99mTc-ECD SPECT: comparison with the manual tracing method

“…The reproducibility and accuracy of the rCBF values obtained using the 3DSRT method have already been reported [16][17][18][19][20][21]. It is thought to be important to understand the differences in the rCBF values obtained using the 3DSRT method and the manual tracing method before the 3DSRT method is widely used.…”

“…Then, the rCBF value in each segment is automatically measured. A number of studies have already demonstrated the reproducibility and accuracy of the rCBF values obtained using the 3DSRT method [16][17][18][19][20][21].…”

A Meta-Analysis of Acupuncture Use in the Treatment of Cognitive Impairment After Stroke

“…The correlation between cognition and cerebral blood flow may partly explain the cognitive-enhancing effect of acupuncture. 34 Dos Santos and colleagues 35 suggested that electroacupuncture may prevent atrophy of some limbic structures, and thus improve cognitive deficits in pilocarpineepileptic rats. The authors of that study postulated that this effect may depend on the serotonergic system.…”