Reaktionen mit Aminoguanidin, II. Umsetzung von Aminoguanidin mit Lactonen und Carbonsäureanhydriden

Ried, Walter; Valentin, Joachim

doi:10.1002/cber.19681010629

Cited by 12 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hapten Synthesis and Verification. the Alfred Bader Library of Rare Chemicals (Milwaukee, WI) or can be prepared from Ñ-aminoguanidine and -butyrolactone by the method of Ried and Valentin (1968). The amino groups in haptens were protected via sulfenylation with 2-nitrobenzenesulfenyl chloride as described below.…”

Section: Instruments Proton Nuclear Magnetic Resonance ( Nmr)mentioning

confidence: 99%

Immunochemical approach to the detection of aminotriazoles using selective amino group protection by chromophores

Jung

Székacs

et al. 1991

J. Agric. Food Chem.

View full text Add to dashboard Cite

A selective approach for amino masking and hapten design for aminotriazole conjugates is described. Haptenic 1,2,4-triazole and 3-amino-l ,2,4-triazole compounds were conjugated to proteins through spacer arms on the C5 ring carbon, containing hydroxyl or mercapto groups. The amino groups present in several haptens were protected via sulfenylation, using a chromophoric protecting reagent, 2-nitrophenylsulfenyl chloride. Protection of haptens, conjugation to proteins, and deprotection on the proteins were followed by UV spectroscopy, monitoring the specific absorbance of the protecting group at 349 nm. Homoand heterobifunctional spacers allowing spacer, hapten, and multiple heterology were used for the protein conjugates for immunizing and coating. Antisera raised against aminotriazole conjugates in New Zealand white rabbits and Swiss Webster mice were found to be specific for amitrole. Inhibition tests resulted in 60% inhibition by amitrole, indicating low-affinity antibodies. Antibody binding to the various antigens synthesized was characterized in a qualitative immunoassay.

show abstract

Section: Instruments Proton Nuclear Magnetic Resonance ( Nmr)mentioning

confidence: 99%

Immunochemical approach to the detection of aminotriazoles using selective amino group protection by chromophores

Jung

Székacs

et al. 1991

J. Agric. Food Chem.

View full text Add to dashboard Cite

show abstract

Chemical Abstract and Journal References for 1,2,4‐Triazoles

1981

Chemistry of Heterocyclic Compounds: A Series of Monographs

View full text Add to dashboard Cite

Theoretische und spektroskopische Untersuchungen an Indigofarbstoffen, XVI. Lichtabsorption und Konstitution der Verknüpfungsisomeren des Indigo

Wille

Lüttke

1973

Chem. Ber.

View full text Add to dashboard Cite

Durch die Synthese der beidcu verbleibenden lndigoisomeren 3-0xo-2-(3-oxo-1 -isoindolinylidenjindolin (5) und 2-0xo-3-(3-oxo-1-isoindolinylidenjindolin (6) wurdc die Gruppe der sechs moglichen Verkniipfungsisomercn 4-9 aus den ,,Halften" Phthalimidin (l), Indoxyl (2) und Oxindol (3) vervollstandigt. An diesen Isomcren und einigen verwandten Tc-Elektronensystemen, die als Bauelemente dieser Verbindungen angesehen wcrden konnen, wurden PPP-Rechnungen ausgefiihrt. Die Rechnungen zeigten, daR die A bsorptionsbanden der Vinylogeil des Iiidigogrundchromophors 7-B bei sehr langen Wellenlangen auftreten sollten. Anhand dicser Vinylogen und einiger anderer Ti-Elektronensysteme konnte die Farbe der Verkniipfungsisomeren 4-9 erkliirt werden. Diese Vorstelliingen uber die Farbe der indigoiden Farbstoffe werden im Hinblick auf das Polymethin-Modell diskutiert. Theoretical and Spectroscopical Investigations on Indigo Dyes, XVI Light Absorption and Constitution of the Combination Isomers of IndigoWith the synthesis of the remaining two indigo isomers 3-oxo-2-(3-oxo-1-isoindolinylidene)indoline (5) and 2-oxo-3-(3-oxo-1-isoindolinylidene)indoline (6) the series of the six possible combination isomers 4-9 of indigo from the ,,halves" phthalimidine (I), indoxyl (2), and oxindole (3) was completed. PPP-calculations were performed on these isomers and some related rc-electron systems that may be considered as building blocks of these compounds. The calculations showed that the absorption bands of vinylogs of the basic indigo chromophore 7-B should occur at very long wave lengths. The colour of the combination isomers 4 -9 could be explained on the basis of these vinylogs and some other Tc-electron systems. These concepts concerning the colour of indigoid dyes are discussed with refcrencc to the polymethinc-model. Im Rahmen unserer Arbeiten iiber Indigofarbstoffe interessierte uns, wie die Lichtabsorption der sechs lsomeren 4-9 des Indigo, die formal durch die Verkniipfung der drei Grundmolekiile Phthalimidin (l), Indoxyl(2) und Oxindol (3) zustande kommen, von ihrer Konstitution abhangt.Von diesen sechs moglichen Isomeren waren bisher nur vier, namlich Bismetaindolon (4)2), Indigo (7), Indirubin (8)') und Isoindigo (9)4) bekannt. Fur das hier 1) XV. Mitteil.: L. Fitjer und W. Liirtke, Chem. Ber. 105, 937 (1972) 2) A . Dunet und A . Willernart, C. R. Acad. Sci. 226, 1286Sci. 226, (1948. 3) A . Wuhl und P. Bugard, Bull. SOC.

show abstract

Reaktionen mit Aminoguanidin, II. Umsetzung von Aminoguanidin mit Lactonen und Carbonsäureanhydriden

Cited by 12 publications

References 8 publications

Immunochemical approach to the detection of aminotriazoles using selective amino group protection by chromophores

Immunochemical approach to the detection of aminotriazoles using selective amino group protection by chromophores

Chemical Abstract and Journal References for 1,2,4‐Triazoles

Theoretische und spektroskopische Untersuchungen an Indigofarbstoffen, XVI. Lichtabsorption und Konstitution der Verknüpfungsisomeren des Indigo

Contact Info

Product

Resources

About