Rapid printing of bio-inspired 3D tissue constructs for skin regeneration

Zhou, Feifei; Hong, Yi; Liang, Renjie; Zhang, Xianzhu; Liao, Youguo; Jiang, Deming; Zhang, Jiayan; Sheng, Zhaohan; Xie, Chang; Peng, Zhi; Zhuang, Xue; Bunpetch, Varitsara; Zou, Yiwei; Huang, Wenwen; Zhang, Qin; Alakpa, Enateri V.; Zhang, Shufang; Ouyang, Hongwei

doi:10.1016/j.biomaterials.2020.120287

Cited by 165 publications

(140 citation statements)

References 70 publications

Supporting

Mentioning

140

Contrasting

Order By: Relevance

“…Some drug delivery systems have been constructed by 3D printing with excellent physico-mechanical properties ( Ng et al, 2016 ; Hafezi et al, 2019 ; Long et al, 2019 ; Karavasili et al, 2020 ). Printing interconnected microchannels ( Zhou et al, 2020 ) containing hydrogel could mimic functions of living skins that facilitates cell migration, proliferation, and new tissue formation.…”

Section: Fabrication Of Hydrogel For Wound Healingmentioning

confidence: 99%

Biomimetic Hydrogels to Promote Wound Healing

Fan

Saha

Hanjaya‐Putra

2021

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Wound healing is a common physiological process which consists of a sequence of molecular and cellular events that occur following the onset of a tissue lesion in order to reconstitute barrier between body and external environment. The inherent properties of hydrogels allow the damaged tissue to heal by supporting a hydrated environment which has long been explored in wound management to aid in autolytic debridement. However, chronic non-healing wounds require added therapeutic features that can be achieved by incorporation of biomolecules and supporting cells to promote faster and better healing outcomes. In recent decades, numerous hydrogels have been developed and modified to match the time scale for distinct stages of wound healing. This review will discuss the effects of various types of hydrogels on wound pathophysiology, as well as the ideal characteristics of hydrogels for wound healing, crosslinking mechanism, fabrication techniques and design considerations of hydrogel engineering. Finally, several challenges related to adopting hydrogels to promote wound healing and future perspectives are discussed.

show abstract

Section: Fabrication Of Hydrogel For Wound Healingmentioning

confidence: 99%

Biomimetic Hydrogels to Promote Wound Healing

Fan

Saha

Hanjaya‐Putra

2021

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

show abstract

“…One emerging research line (the papers was not included in this scientometric analysis) illustrates the significant advances in the cell source-related technologies aimed at generating a safe and effective cell source for clinical use[ 112 - 114 ]. Nevertheless, the vast majority of the bioprinting studies conducted today use cells to develop proof-of-concept tissue constructs rather than functional tissues for transplantation[ 111 , 115 ].…”

Section: Bioinks For Different Bioprinting Technologiesmentioning

confidence: 99%

Bioinks for 3D Bioprinting: A Scientometric Analysis of Two Decades of Progress

Pedroza-González¹,

Rodríguez-Salvador²,

Pérez-Benítez³

et al. 2021

ijb

View full text Add to dashboard Cite

This scientometric analysis of 393 original papers published from January 2000 to June 2019 describes the development and use of bioinks for 3D bioprinting. The main trends for bioink applications and the primary considerations guiding the selection and design of current bioink components (i.e., cell types, hydrogels, and additives) were reviewed. The cost, availability, practicality, and basic biological considerations (e.g., cytocompatibility and cell attachment) are the most popular parameters guiding bioink use and development. Today, extrusion bioprinting is the most widely used bioprinting technique. The most reported use of bioinks is the generic characterization of bioink formulations or bioprinting technologies (32%), followed by cartilage bioprinting applications (16%). Similarly, the cell-type choice is mostly generic, as cells are typically used as models to assess bioink formulations or new bioprinting methodologies rather than to fabricate specific tissues. The cell-binding motif arginine-glycine-aspartate is the most common bioink additive. Many articles reported the development of advanced functional bioinks for specific biomedical applications; however, most bioinks remain the basic compositions that meet the simple criteria: Manufacturability and essential biological performance. Alginate and gelatin methacryloyl are the most popular hydrogels that meet these criteria. Our analysis suggests that present-day bioinks still represent a stage of emergence of bioprinting technology.

show abstract

“…Extrusion techniques result in lower cell viability where extrusion volume and nozzle size influence cell survival. It has been proposed that the droplet size will range from 1 pL to 300 pL with a printing rate of 10,000 droplets per second, enabling the production of long or thin lines up to 50 μ [26].…”

Section: Bio Printing In Tissue Engineeringmentioning

confidence: 99%

The amber nano fibers development prospects to expand the capabilites of textile 3D printing in the general process of fabrication methods

Viļuma-Gudmona

Ļašenko

Sanchaniya

et al. 2021

20th International Scientific Conference Engineering for Rural Development Proceedings

View full text Add to dashboard Cite

The amber nano fibres are bio-active composites which could be applied in three-dimensional printing. The idea of using the amber for creating a new 3D printing material, including technological composition of the innovative amber nano and micro fibres is based on the hypothesis that organic compounds of succinite have an effective impact on living cells, including reparative, stimulating, for sedative effects as well protective properties from electro-magnetic field. To produce amber nano fibres, bioactive components were used that were isolated from the succinite and tested (in vitro) in the scientific laboratories. Three-dimensional printing is an emerging technology, which has been initially used to design and generate three-dimensional structures mainly for transplantation therapies. This process, which can be used for a variety of polymers, is becoming an increasingly essential component of biotechnological advancements. This article discusses the foundations of this technology, namely the processes used in conventional three-dimensional printing; it also discusses tissue engineering, a discipline of which new implementations of this technology are used as bio printing. The shortcomings of tissue engineering are addressed, including the failure of existing technology to manufacture nanofiber-based constructs used in blood vessels, cartilage, artery valves, tendon, cardiac muscle valves, muscle, and cornea. From this need for nanofiber processing, electrospinning is proposed as a possible roadmap for imminent tissue engineering threedimensional printing technologies, and finally, the latest integration of this technology with three-dimensional printing is addressed, highlighting the existing shortcomings in maintaining mandatory nano resolutions.

show abstract

Rapid printing of bio-inspired 3D tissue constructs for skin regeneration

Cited by 165 publications

References 70 publications

Biomimetic Hydrogels to Promote Wound Healing

Biomimetic Hydrogels to Promote Wound Healing

Bioinks for 3D Bioprinting: A Scientometric Analysis of Two Decades of Progress

The amber nano fibers development prospects to expand the capabilites of textile 3D printing in the general process of fabrication methods

Contact Info

Product

Resources

About