Quercetin loaded biopolymeric colloidal particles prepared by simultaneous precipitation of quercetin with hydrophobic protein in aqueous medium

Patel, Ashok R.; Heussen, Patricia C.M.; Hazekamp, Johan; Drost, Ellen; Velikov, Krassimir P.

doi:10.1016/j.foodchem.2012.01.054

Cited by 185 publications

(80 citation statements)

References 39 publications

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“…Quercetin displays an amphipathic behavior due to the phenyl rings that form the hydrophobic part of the molecule and the hydroxyl groups constituting the polar portion. However, quercetin solubility in water is poor, which can explain the formation of quercetin crystals and their presence in the surface (Srinivas et al 2010;Patel et al 2012). The results are in agreement with Norajit et al (2010) that showed the effect of the incorporation of red ginseng extract on alginate-based film, where the surface smoothness of alginate film was changed with the appearance of a fibrous surface.…”

Section: Resultssupporting

confidence: 80%

Development and Characterization of an Active Chitosan-Based Film Containing Quercetin

Souza

Vaz

Silva

et al. 2015

Food Bioprocess Technol

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This work aims at developing an active chitosan film through the incorporation of quercetin and the evaluation of physical and functional properties of the films made thereof. The addition of quercetin showed to influence films' properties in terms of surface morphology, tensile strength, and opacity while elongation-at-break, thickness, water vapor, and oxygen permeability were not significantly affected with incorporation of quercetin. The color parameters of chitosan films were affected by quercetin incorporation with a decrease of the values of L* and a*. The film exhibited a high freeradical scavenging activity, showing antioxidant activity. The film-forming solutions of chitosan with or without quercetin showed antibacterial activity against four Gram-negative and three Gram-positive bacteria. These results showed that quercetin incorporation in chitosan-based films has potential to be used as a solution for active food packaging.

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Section: Resultssupporting

confidence: 80%

Development and Characterization of an Active Chitosan-Based Film Containing Quercetin

Souza

Vaz

Silva

et al. 2015

Food Bioprocess Technol

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“…9,10 These proteins have been extensively investigated because of their ability to form nanoparticles (NPs) for the encapsulation of bioactive compounds, such as essential oils, 11,12 and also for controlled drug delivery for biomedical applications. 13,14,10 Because of their high biocompatibility and ability to form nanospheres through coacervation, zeins are natural raw materials with potential uses in tissue engineering, drug delivery systems, and biomedicine. 1,15 Biodegradable NPs have received considerable attention because of their potential usefulness in the development of strategies for the topical delivery of oils and therapeutic drugs, [16][17][18] particularly when drug penetration into the dermis is desirable.…”

Section: Introductionmentioning

confidence: 99%

Biodegradable Nanoparticles Obtained From Zein as a Drug Delivery System for Terpinen-4-Ol

Marini¹,

Martelli²,

Zornio³

et al. 2014

Química Nova

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Biodegradable nanoparticles (NPs) have received considerable attention because of their possible use in the development of strategies for the topical delivery of oils and therapeutic drugs, particularly when drug penetration in dermis is desired. Zein is a prolamine and is a promising material for the design of drug delivery systems. In this study, NPs were prepared with zein and were used to encapsulate and release terpinen-4-ol, which is a therapeutic agent for the treatment of melanoma. The results show that the zein NPs are promising nanostructured systems for the prolonged delivery of T4OL with potential applications in anti-melanoma therapy.

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“…Zein films and zein micro/nano particles can be used for encapsulation of essential oils, aromas and flavors, controlled release of active additives and as an active food packaging material, etc. (Alkan et al, 2011;Parris, Cooke, & Hicks, 2005;Patel, Heussen, Hazekamp, Drost, & Velikov, 2012;Sanchez-Garcia, Hilliou, & Lagaron, 2010;Shi, Kokini, & Huang, 2009;Zhong, Jin, Davidson, & Zivanovic, 2009). In the recent years, electrospinning of zein nanofibers have received much attention as well (Jiang, Reddy, & Yang, 2010;Jiang & Yang, 2011;Jiang, Zhao, & Zhu, 2007;Miyoshi, Toyohara, & Minematsu, 2005;Selling et al, 2007Torres-Giner, Gimenez, & Lagaron, 2008;).…”

Section: Introductionmentioning

confidence: 99%

Electrospun zein nanofibers incorporating cyclodextrins

Kayacı

Uyar

2012

Carbohydrate Polymers

129

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a b s t r a c tZein nanofibers containing cyclodextrins (zein/CD) were produced via electrospinning. Three types of CDs (␣-CD, ␤-CD and ␥-CD) having 10%, 25% and 50% (w/w) were individually incorporated into zein nanofibers. SEM imaging elucidated that the morphologies of the electrospun zein/CD nanofibers depended on the CD type and weight percentage. The incorporation of CDs in zein improved the electrospinnability and bead-free nanofibers were obtained at lower zein concentrations. Zein/CD nanofibers having fiber diameters ∼100-400 nm were obtained depending on the zein concentrations, types and weight percentages of CD. XRD studies revealed that CDs were mostly distributed without forming crystalline aggregates for zein/CD nanofibers containing lower weight percentage of CDs. The surface analyses of zein/CD nanofibers by ATR-FTIR and XPS indicated that some of the CDs were present on the fiber surface. Thermal analyses showed that zein/␤-CD nanofibers have shown higher glass transition temperatures and higher degradation temperature with increasing CD content.

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Quercetin loaded biopolymeric colloidal particles prepared by simultaneous precipitation of quercetin with hydrophobic protein in aqueous medium

Cited by 185 publications

References 39 publications

Development and Characterization of an Active Chitosan-Based Film Containing Quercetin

Development and Characterization of an Active Chitosan-Based Film Containing Quercetin

Biodegradable Nanoparticles Obtained From Zein as a Drug Delivery System for Terpinen-4-Ol

Electrospun zein nanofibers incorporating cyclodextrins

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