Development and Characterization of an Active Chitosan-Based Film Containing Quercetin

Abstract

This work aims at developing an active chitosan film through the incorporation of quercetin and the evaluation of physical and functional properties of the films made thereof. The addition of quercetin showed to influence films' properties in terms of surface morphology, tensile strength, and opacity while elongation-at-break, thickness, water vapor, and oxygen permeability were not significantly affected with incorporation of quercetin. The color parameters of chitosan films were affected by quercetin incorporation with a decrease of the values of L* and a*. The film exhibited a high freeradical scavenging activity, showing antioxidant activity. The film-forming solutions of chitosan with or without quercetin showed antibacterial activity against four Gram-negative and three Gram-positive bacteria. These results showed that quercetin incorporation in chitosan-based films has potential to be used as a solution for active food packaging.

Flavonoid interaction with chitosan: planning active packing with antioxidant and antimicrobial activity

“…The present study is similar to other experimental studies developed, where flavonoid quercetin was used as an additive and incorporated into chitosan efficiently [19][20][21]. …”

Investigation of antioxidant activity and release kinetics of curcumin from tara gum/ polyvinyl alcohol active film

“…Because of consumer health concerns, current research has focused on natural active compounds rather than synthetic compounds. These natural compounds include those in green-tea extract (Siripatrawan & Harte, 2010), quercetin (Souza et al, 2015), grapeseed extract (Moradi et al, 2012), atocopherol (Melo, Arrivetti, Alencar, & Skibsted, 2016), pomegranate-rind extract (Qin et al, 2015), curcumin (Etxabide, Coma, Guerrero, Gardrat, & de la Caba, 2017) and essential oils (Moradi, Tajik, Rohani, & Mahmoudian, 2016). Among these natural active compounds, curcumin, which is a polyphenolic compound that is isolated from turmeric powder, has been used extensively in medicine because of its desirable antioxidant, antitumor and antiinflammatory activities (Sonkaew, Sane, & Suppakul, 2012).…”

“…Sun et al fabricated a poly(glycerolesebacateecurcumin) polymer for possible use in healing brain gliomas (Sun et al, 2013); Baipai et al prepared an antioxidant film made from curcumin, cellulose microcrystals and chitosan for wound healing (Bajpai, Chand, & Ahuja, 2015a). Bitencourt et al prepared gelatin-based films that were activated with curcuma ethanol extract for food packaging (Bitencourt, F avaro-Trindade, Sobral, & Carvalho, 2014).…”

Properties of novel chitosan incorporated with hexahydro‐β‐acids edible films and its effect on shelf life of pork

“…Materials used to form films or coatings are usually rich in polysaccharides such as starch (Medina Jaramillo, Gutiérrez, Goyanes, Bernal, & Famá, 2016), carboxymethyl cellulose (Martelli et al., 2017), and chitosan (CH) (Azevedo et al., 2014; Mohamed, Clementine, Didier, Gérard, & Marie Noëlle, 2013), and proteins such as whey protein (Seydim & Sarikus, 2006), soy protein isolate (Emiroğlu, Yemiş, Coşkun, & Candoğan, 2010), gelatin (Podshivalov, Zakharova, Glazacheva, & Uspenskaya, 2017) and lipids, including waxes (Singh et al., 2016), and so on. Among these, CH is widely used to prepare edible antibacterial films due to its biocompatibility, biodegradation, and excellent film‐forming properties (Genskowsky et al., 2015) as well as antibacterial activity against bacteria and fungi (Lago et al., 2014; Mohamed et al., 2013; Souza et al., 2015). CH, a linear polysaccharide (poly‐glucose‐acetylamino), is a natural nontoxic biopolymer produced by partial or total de‐N‐acetylation of chitin, which is derived from the shells of shrimps and crab.…”