Quantum Dots and Their Multimodal Applications: A Review

Bera, Debasis; Liu, Qian; Tseng, T.K.; Holloway, Paul H.

doi:10.3390/ma3042260

Cited by 1,090 publications

(661 citation statements)

References 379 publications

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“…For example, quantum dots (QDs), as semiconductors, can be excited by chemical and electrochemical reactions. The light emission of QDs controlled by the applied electrode potential enables them to be applied as excellent ECL labels for bioassays [9]. The use of CdTe QDs as the luminophor and K 2 S 2 O 8 as the coreactant is the most popular system in sandwichenhanced ECL immunoassays.…”

Section: Nanoparticle-functionalized Nanoprobes For Signal Amplificationmentioning

confidence: 99%

Signal Amplification for Highly Sensitive Immunosensing

2017

J. Anal. Test.

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To dissolve the bottleneck problem of life and biomedical science in detection of biomolecules with low abundance and acquisition of ultraweak biological signals, highly sensitive analytical methods coupling with the specificity of biological recognition events have been quickly developed by the exploring of signal amplification strategies. These strategies have extensively been introduced into the development of highly sensitive immunosensing methods by combining with highly specific immunological recognition. They can be divided into two groups. One group of strategies attempts to transfer the immunological recognition event into large number of reporter probes or signal probes for signal readout by employing nano/micro-materials as vehicles for multi-labeling and/or molecular biological amplification for increasing the abundance of the signal molecules. The other uses nanomaterials or enzyme mimics as catalytic tools/tags to obtain enhanced detection signal. This review focuses on the significant advances in design of signal amplification strategies for highly sensitive immunosensing.

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Section: Nanoparticle-functionalized Nanoprobes For Signal Amplificationmentioning

confidence: 99%

Signal Amplification for Highly Sensitive Immunosensing

2017

J. Anal. Test.

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“…It is an allotrope of carbon whose structure is a single planar sheet of sp2-bonded carbon atoms that are densely packed in a honeycomb crystal lattice. Hence, graphenes may be considered as the mother of graphite, fullerene and CNTs (Bera et al, 2010).…”

Section: Carbon Allotrope Graphenesmentioning

confidence: 99%

A review of nanotechnology with an emphasis on Nanoplex

Kadam

Shendge

Pande

2015

Braz. J. Pharm. Sci.

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The use of nanotechnology based on the development and fabrication of nanostructures is one approach that has been employed to overcome the challenges involved with conventional drug delivery systems. Formulating Nanoplex is the new trend in nanotechnology. A nanoplex is a complex formed by a drug nanoparticle with an oppositely charged polyelectrolyte. Both cationic and anionic drugs form complexes with oppositely charged polyelectrolytes. Compared with other nanostructures, the yield of Nanoplex is greater and the complexation efficiency is better. Nanoplex are also easier to prepare. Nanoplex formulation is characterized through the production yield, complexation efficiency, drug loading, particle size and zeta potential using scanning electron microscopy, differential scanning calorimetry, X-ray diffraction and dialysis studies. Nanoplex have wide-ranging applications in different fields such as cancer therapy, gene drug delivery, drug delivery to the brain and protein and peptide drug delivery.Uniterms: Nanotechnology. Nanoplex/formulation. Nanoplex/characterization. Nanoplex/applications O uso da nanotecnologia baseada no desenvolvimento e na fabricação de nanoestruturas é uma abordagem que tem sido empregada para superar os desafios envolvidos nos sistemas de liberação de fármacos convencionais. A formulação de nanoplexos é a nova tendência na nanotecnologia. Um nanoplexo é um complexo formado pela nanopartícula do fármaco com poplieletrólito de carga oposta. Tanto fármacos catiônicos quanto aniônicos formam complexos com polieletrólitos opostamente carregados. Comparado com outras nanoestruturas, o rendimento dos nanoplexos é maior e a eficiência de complexação é melhor. Nanoplexos são, também. De mais fácil preparação. A formulação de nanoplexo é caracterizada pelo rendimento de produção, eficiência de complexação, carga do fármaco, tamanho de partícula e potencial zeta, utilizando microscopia eletrônica de varredura, calorimetria exploratória diferencial, difração de raios X e estudos de diálise. Os nanoplexos têm aplicações amplas em diferentes campos, como terapia antineoplásica, liberação em terapia gênica, liberação cerebral de fármaco, liberação de fármacos protéicos e peptídicos.Unitermos: Nanotecnologia. Nanoplexos/formulação. Nanoplexos/caracterização. Nanoplexos/ aplicações.

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“…The method of using oleic acid as the capping agent has been used before in other systems with different solvents to produce highly luminescence materials. [4,[24][25][26] The use of 1-octadecene/oleic acid/TOP system had not been used up to this point. It was found that this system produced a highly stable colloidal suspension.…”

Section: Hot Injection Methods Of Quantum Dot Synthesismentioning

confidence: 99%

“…It is also at a constant temperature which will dictate what the saturation pressure will be. * 1 = 1 1 1 [4] As mentioned before, the polymer is considered nonvolatile and the only component this equation is in reference to is the solvent, such as chloroform, water, or some other liquid. The activity coefficient, γ, will be calculated using the Flory-Huggins…”

Section: Polymer Layer Deposition and Characterizationmentioning

confidence: 99%

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Synthesis of cadmium selenide quantum dots for fabrication of hybrid light emitting diodes.

McCreary¹

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McCreary, Michael 1991-, "Synthesis of cadmium selenide quantum dots for fabrication of hybrid light emitting diodes." (2014 ABSTRACTThe synthesis of CdSe quantum dots was carried out using a variety of methods including co-precipitation method, reverse micellar method, and hot injection method. Of these three methods, only the hot injection method produced an immediately viable product for application in the hybrid light emitting diode proposed. The co-precipitation method did generate the ability to perform the reverse micellar method which produced ~30 nm diameter nanorods of mostly amorphous material. These rods were analyzed using XRD, and TEM. The hot injection method using octadecene as the solvent and various ligands, including oleic acid, benzene-1,4-dithiol, mercapto-benzoic acid and TOP, created quantum dots exhibiting photoluminescence in the green region of the visible spectrum. These quantum dots were characterized using UV-Visible Spectroscopy and Photoluminescence Spectroscopy. The oleic acid capped QD had a characteristic wavelength of 560 nm. While the mercapto-benzoic acid and benzene-1,4-dithiol capped QD had a characteristic wavelengths of 510 nm and 555 nm, respectively, all under the same operating conditions. For the purposes of device fabrication, the NN-Labs QDs vii were mostly used because their performance was much better than quantum dots synthesized in house.The fabrication of a hybrid light emitting diode has been developed with the structure ITO/PEDOT:PSS/PVK/CdSe QD/Alq3/Al. The device has exhibited a turn-on voltage from 2-3 V with currents ranging from 4-5 mA. The PEDOT:PSS layer was deposited using spin coating and analyzed using Photoluminescence Spectroscopy, Atomic Force Microscopy, Optical Microscopy, and Surface Profiling. The layer produce is sufficient for device fabrication. To facilitate proper hole transport and a sufficient quantum dot layer, a PVK/QD composite solution was used to create a monolayer layer of quantum dots by phase separation of the solutes in the solution. Alq3 and Al were deposited using thermal evaporation techniques.viii

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Quantum Dots and Their Multimodal Applications: A Review

Cited by 1,090 publications

References 379 publications

Signal Amplification for Highly Sensitive Immunosensing

Signal Amplification for Highly Sensitive Immunosensing

A review of nanotechnology with an emphasis on Nanoplex

Synthesis of cadmium selenide quantum dots for fabrication of hybrid light emitting diodes.

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