Quantitative Immunochemical Determination of Lysozyme (Muramidase) in Serum and Urine

Johansson, Benny; Malmquist, Jörgen

doi:10.3109/00365517109080216

Cited by 91 publications

(26 citation statements)

References 17 publications

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“…These cases comprised 2 females with oral contraceptive hypertension and 1 male with Alport's syndrome. In the 46 patients DISCUSSION Determination of muramidase in serum and urine by means of the present principle was first reported by Johansson & 'Malmquist (9). Their modification of the method differs from the present one.…”

Section: Resultsmentioning

confidence: 87%

Renal Handling of Muramidase in Patients with Kidney Diseases or Hypertension

Jensen

1973

Scandinavian Journal of Clinical and Laboratory Investigation

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Jensen, H. Renal Handling of Murarnidase in Patients with Kidney Diseases or Hypertension. Scand. 1. din. Lab. Invest. 32. 11 1-1 15, 1973. By means of electrophoresis in antibodycontaining agarose gel, serum and urine rnuramidase were quantitated in 79 patients with renal disease or hypertension. In patients with a normal glornerular filtration rate, an increased urinary excretion of muramidase was found in only 3 of 33 cases. The diagnosis in these 3 cases was: Alport's syndrome (I case), hypertension from oral contraceptives (2 cases). In 46 patients with a decreased glomerular filtration rate, the urinary excretion of muramidase was increased in 29 cases. It is concluded that rnuramidasuria in chronic renal disorders is determined by the magnitude of the glomerular filtration rate and not by the aetiology of the renal disease.

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Section: Resultsmentioning

confidence: 87%

Renal Handling of Muramidase in Patients with Kidney Diseases or Hypertension

Jensen

1973

Scandinavian Journal of Clinical and Laboratory Investigation

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“…Immunochemical lysozyme determinations, as described by Johansson and Malmquist (1971), can be expected to give more accurate information about the true lysozyme concentration in serum and urine.…”

Section: Discussionmentioning

confidence: 99%

“…HL was isolated from the urine of a patient suffering from nephrocalcinosis and renal tubular acidosis. The isolation was carried out according to the procedure of Johansson and Malmquist (1971). The purity of the lysozyme preparation was checked electrophoretically in agarose gel.…”

Section: Methodsmentioning

confidence: 99%

Reliability of enzymatic lysozyme determinations.

Tepper¹,

Meijer²,

Brouwer-Pijpen³

1976

Journal of Clinical Pathology

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“…Crude papain, free of lysozyme activity, was dissolved in 0.9% NaCl (10 mg/ml) and clarified with a 0. 22 were obtained from Sigma Chemical Co. All other reagents were analytical grade.…”

Section: Methodsmentioning

confidence: 99%

Effects of acute cartilaginous injury on serum and cartilage lysozyme levels

Greenwald¹,

Cantor²,

Schwartz³

et al. 1975

Arthritis & Rheumatism

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Acute cartilage degradation was produced in rabbits by the intravenous injection of crude papain. This resulted in a significant rise in serum lysozyme in 97% of the animals, as well as a fall in the residual lysozyme content of auricular and costal cartilage. The rise in serum lysozyme paralleled the rise in serum chondroitin sulfate. The source of the rise in lysozyme appeared to be the release of extracellular, nonlysosomal lysozyme from the cartilage matrix. Serum lysozyme elevation in arthritic disorders may reflect cartilage degradation.

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Quantitative Immunochemical Determination of Lysozyme (Muramidase) in Serum and Urine

Cited by 91 publications

References 17 publications

Renal Handling of Muramidase in Patients with Kidney Diseases or Hypertension

Renal Handling of Muramidase in Patients with Kidney Diseases or Hypertension

Reliability of enzymatic lysozyme determinations.

Effects of acute cartilaginous injury on serum and cartilage lysozyme levels

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