Protective effect of pristine C60 fullerene nanoparticle in combination with curcumin against hyperglycemia‐induced kidney damage in diabetes caused by streptozotocin

Demir, Ersin; Aslan, Abdullah Nabi

doi:10.1111/jfbc.13470

Cited by 16 publications

(6 citation statements)

References 64 publications

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“…In addition, some studies found that diabetes mellitus is associated with the generation of free radicals and/or antioxidant defense system (Adam et al, 2017). The continue generation of ROS in high blood glucose conditions has been found to bring about oxidative stress involved in the damage of islet of b‐cell function (Abhishek et al, 2019; Demir & Aslan, 2020). While on the contrary, free radicals could cause harmful oxidation by attacking macromolecules including carbohydrate, lipids, and proteins (Adam et al, 2017).…”

Section: Resultsmentioning

confidence: 99%

Antioxidant and antidiabetic activities of vanadium‐binding protein and trifuhalol A

Zhang

Kim

Liu³

et al. 2020

J. Food Biochem.

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Diabetes mellitus has become a major global health problem due to increasing morbidity among all age groups. It has been reported that the number of patients with diabetes was more than 450 million in 2017, and would reach to 693 million on 2045 (Makinde et al., 2019). Diabetes mellitus is considered as a chronic and systemic metabolic disease which is associated with insulin deficiency (type 1) and insulin resistance or insulin insensitiveness (type 2) (Chausmer, 1998; De Liefde et al., 2005). The high blood glucose level could lead to hypertension, hyperlipidemia, weight gain, or obesity (Ahmed et al., 2019). It is well known that the destruction of pancreatic β cells can cause insulin deficiency and further develop into diabetes (Yoon & Jun, 2005). The pancreatic β cells are highly sensitive toward oxidative stress, which

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Section: Resultsmentioning

confidence: 99%

Antioxidant and antidiabetic activities of vanadium‐binding protein and trifuhalol A

Zhang

Kim

Liu³

et al. 2020

J. Food Biochem.

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“…The C60 has been widely employed in PDT 46 . Moreover, C60 fullerene has been considered a potent therapeutic agent for the treatment of diseases such as cancer, diabetes, Parkinson's, and Alzheimer's 47 …”

Section: Carbon Nanomaterialsmentioning

confidence: 99%

Theranostic applications of multifunctional carbon nanomaterials

Asil

Guerrero

Bugarini

et al. 2023

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Nanobiotechnology is one of the leading research areas in biomedical science, developing rapidly worldwide. Among various types of nanoparticles, carbon nanomaterials (CNMs) have attracted a great deal of attention from the scientific community, especially with respect to their prospective application in the field of disease diagnosis and therapy. The unique features of these nanomaterials, including favorable size, high surface area, and electrical, structural, optical, and chemical properties, have provided an excellent opportunity for their utilization in theranostic systems. Carbon nanotubes, carbon quantum dots, graphene, and fullerene are the most employed CNMs in biomedical fields. They have been considered safe and efficient for non‐invasive diagnostic techniques such as fluorescence imaging, magnetic resonance imaging, and biosensors. Various functionalized CNMs exhibit a great capacity to improve cell targeting of anticancer drugs. Due to their thermal properties, they have been extensively used in cancer photothermal and photodynamic therapy assisted by laser irradiation and CNMs. CNMs also can cross the blood‐brain barrier and have the potential to treat various brain disorders, for instance, neurodegenerative diseases, by removing amyloid fibrils. This review has summarized and emphasized on biomedical application of CNMs and their recent advances in diagnosis and therapy.

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“…Nanocarbon particles may be of clinical use for the treatment of non-life-threatening diseases, such as diabetes mellitus, [66][67][68][69][70][71][72][73][74][75][76][77][78][79][80][81][82][83][84][85] and in bone regenerative medicine. [27,33,[86][87][88] The safety assessment approaches are exactly the same as in application (2), although the principle of therapeutic effect versus risk requires much more stringent standards.…”

Section: Administration Of Nanocarbon Particles Locally In Non-life-t...mentioning

confidence: 99%

Future Prospects for Clinical Applications of Nanocarbons Focusing on Carbon Nanotubes

et al. 2022

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Over the past 15 years, numerous studies have been conducted on the use of nanocarbons as biomaterials towards such applications as drug delivery systems, cancer therapy, and regenerative medicine. However, the clinical use of nanocarbons remains elusive, primarily due to short‐ and long‐term safety concerns. It is essential that the biosafety of each therapeutic modality be demonstrated in logical and well‐conducted experiments. Accordingly, the fundamental techniques for assessing nanocarbon biomaterial safety have become more advanced. Optimal controls are being established, nanocarbon dispersal techniques are being refined, the array of biokinetic evaluation methods has increased, and carcinogenicity examinations under strict conditions have been developed. The medical implementation of nanocarbons as a biomaterial is in sight. With a particular focus on carbon nanotubes, these perspectives aim to summarize the contributions to date on nanocarbon applications and biosafety, introduce the recent achievements in evaluation techniques, and clarify the future prospects and systematic introduction of carbon nanomaterials for clinical use through practical yet sophisticated assessment methods.

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Protective effect of pristine C60 fullerene nanoparticle in combination with curcumin against hyperglycemia‐induced kidney damage in diabetes caused by streptozotocin

Cited by 16 publications

References 64 publications

Antioxidant and antidiabetic activities of vanadium‐binding protein and trifuhalol A

Antioxidant and antidiabetic activities of vanadium‐binding protein and trifuhalol A

Theranostic applications of multifunctional carbon nanomaterials

Future Prospects for Clinical Applications of Nanocarbons Focusing on Carbon Nanotubes

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