W. orientalis is a one-year herbaceous plant, located in the Lamiaceae family, and is called Ballıbaba in Turkish. In the presented study, the antimicrobial and anticancer properties of flowers extracts of endemic W. orientalis were investigated for the first time. Also, it was investigated the antiradical activity and phytochemical contents of this plant extracts. According to our study results, endemic W. orientalis flowers extract show very high anticancer activity against MCF-7, HCT-116 and LNCaP cancer cell lines, high antiradical activity against ABTS radicals, and effective antimicrobial activity against some microorganism caused infection in humans. In conclusion, endemic W. orientalis can be used as an anticancer and antimicrobial agent and this plant can be the subject of further studies in the field of herbal medicine.
Hypericum scabrum L. has been widely used in traditional medicine for the treatment of many diseases just as the other Hypericum species. In the present study, the antiradical, antimicrobial and cytotoxic activities of water and ethanol extracts of H. scabrum flowers were investigated. Their phytochemical contents and composition were also determined. The water and ethanol extracts are better scavenged ABTS (97.89 and 98.99%) and OH radicals (96.36 and 97.33%); the water extract is better scavenged DPPH radicals (91.66%) than the standard antioxidant BHA (94.33, 85.19, 90.16%, respectively). Flowers of H. scabrum contain flavonoids, phenolic acids, vitamins and phytosterols, dominated by catechin, vanillic acid, vitamin K and ergosterol. The extracts exhibit a strong cytotoxic activity against MCF-7, HCT-116, and LNCaP cancer cell lines. It is found that their antimicrobial activities are higher than the standard antibiotics. These results indicate that H. scabrum flowers have potent antiradical, antimicrobial and cytotoxic activities.
Rheum ribes L. (rhubarb) is belonging to Polygonaceae, and its roots and fresh shoots are consumed as vegetable in Turkey. This plant is considered to be one of the most important pharmaceutical raw materials in Middle East.In this study, the antiradical, antimicrobial, cytotoxic and bioactive properties of water, ethanol, and methanol extracts of R. ribes stems were determined. R. ribes stems water, ethanol and methanol extracts are better
Monodisperse Pd/Co nanoparticles (Mw−Pd/Co@CNT NPs) decorated multi‐walled carbon nanotubes have been reproducibly and easily synthesized by microwave assisted method. They were found to be remarkable catalysts for the preparation of tetrazole derivatives which have significant benefits in wide range of drug purposes. Mw−Pd/Co@CNT NPs were characterized by X‐ray diffraction (XRD), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HR‐TEM) and X‐ray photoelectron spectroscopy (XPS). The results showed the fact that the prepared catalysts are highly crystalline, monodisperse and colloidally stable. The catalytic performance of these NPs was examined for any preparation of tetrazole derivatives and it's found that these Mw−Pd/Co@CNT NPs showed extraordinary catalytic activity, stability and durability. All products were provided with perfect yield in addition to shortest reaction time by employing Mw−Pd/Co@CNT as a heterogeneous catalyst. Our synthesis process comes with a facile and eco‐friendly option to Mw−Pd/Co@CNT, allowing further scrutiny of current catalysts for numerous other chemical reactions.
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