Propiedades psicométricas y utilidad diagnóstica del Addenbrooke's Cognitive Examination-Revised (ACE-R) en una muestra de ancianos chilenos

Muñoz-Neira, Carlos; Henríquez, Fernando; J, Josefina Ihnen; C, Mauricio Sánchez; M, Patricia Flores; Slachevsky, Andrea

doi:10.4067/s0034-98872012000800006

Cited by 40 publications

(22 citation statements)

References 27 publications

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“…All participants were also tested with global cognitive efficiency measures: [1] the Mini Mental State Examination (MMSE), 28 the most commonly used cognitive screening test internationally; 29 and [2] the Addenbrooke's Cognitive Examination Revised- Chilean Version (ACE-R-Ch), 30 a test that assesses five cognitive domains: orientation and attention, memory, verbal fluency, language and visuospatial abilities.…”

Section: Methodsmentioning

confidence: 99%

Chilean version of the INECO Frontal Screening (IFS-Ch): Psychometric properties and diagnostic accuracy

Ihnen

Antivilo

Muñoz-Neira

et al. 2013

Dement. neuropsychol.

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OBJECTIVEThis study sought to analyze the psychometric properties and diagnostic accuracy of the Chilean version of the INECO Frontal Screening (IFS-Ch) in a sample of dementia patients and control subjects.METHODSAfter adapting the instrument to the Chilean context and obtaining content validity evidence through expert consultation, the IFS-Ch was administered to 31 dementia patients and 30 control subjects together with other executive assessments (Frontal Assessment Battery [FAB], Modified version of the Wisconsin Card Sorting Test [MCST], phonemic verbal fluencies [letters A and P] and semantic verbal fluency [animals]) and global cognitive efficiency tests (Mini mental State Examination [MMSE] and Addenbrooke's Cognitive Examination-Revised [ACE-R]). Caregivers of dementia patients and proxies of control subjects were interviewed with instruments measuring dysexecutive symptoms (Dysexecutive Questionnaire [DEX]), dementia severity (Clinical Dementia Rating Scale [CDR]) and functional status in activities of daily living (Activities of Daily Living Scale [IADL] and Technology-Activities of Daily Living Questionnaire [T-ADLQ]). Convergent and discriminant validity, internal consistency reliability, cut-off points, sensitivity and specificity for the IFS-Ch were estimated.RESULTSEvidence of content validity was obtained. Evidence of convergent validity was also found showing significant correlations (p<0.05) between the IFS-Ch and the other instruments measuring: executive functions (FAB, r=0.935; categories achieved in the MCST, r=0.791; perseverative errors in the MCST, r= -0.617; animal verbal fluency, r=0.728; "A" verbal fluency, r=0.681; and "P" verbal fluency, r=0.783), dysexecutive symptoms in daily living (DEX, r= -0.494), dementia severity (CDR, r= -0.75) and functional status in activities of daily living (T-ADLQ, r= -0.745; IADL, r=0.717). Regarding reliability, a Cronbach's alpha coefficient of 0.905 was obtained. For diagnostic accuracy, a cut-off point of 18 points (sensitivity=0.903; specificity=0.867) and an area under curve of 0.951 were estimated to distinguish between patients with dementia and control subjects.DISCUSSIONThe IFS-Ch showed acceptable psychometric properties, supported by evidence of validity and reliability for its use in the measurement of executive functions in patients with dementia. The diagnostic accuracy of the IFS-Ch for detecting dementia patients was also considered acceptable.

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Section: Methodsmentioning

confidence: 99%

Chilean version of the INECO Frontal Screening (IFS-Ch): Psychometric properties and diagnostic accuracy

Ihnen

Antivilo

Muñoz-Neira

et al. 2013

Dement. neuropsychol.

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“…Briefly, AD patients displayed a history of significant episodic memory loss, within the context of a preserved behavioral and personality score above 0.5 on the Clinical Dementia Rating scale (CDR) (25 with CDR = 1; 8 patients with CDR = 2; 2 with CDR = 3) [25]. CN subjects did not report memory complaints, had a score of 0 on the CDR [25], and their cognitive performance was considered as normal according to local normative data for the Addenbrooke's Cognitive Examination -Revised Chilean Version (ACE-R-Ch) (>76) [26]. Scores of the FCSRT were not considered to establish the diagnosis.…”

Section: Participantsmentioning

confidence: 99%

“…Concerning neuropsychological assessment, experienced clinical psychologists extensively trained at conducting neuropsychological evaluations (CMN and FH) and blinded to the condition of each subject administered a battery of tools that, in addition to both Word and Picture FCSRT versions to measure episodic memory, included the Mini-Mental State Examination (MMSE) [27], the Montreal Cognitive Assessment (MoCA) [28], and the Addenbrooke's Cognitive Examination-Revised, Chilean version (ACE-R-Ch) [26] …”

Section: Clinical and Neuropsychological Examinationmentioning

confidence: 99%

Neuroanatomical Comparison of the “Word” and “Picture” Versions of the Free and Cued Selective Reminding Test in Alzheimer’s Disease

Slachevsky

Barraza

Hornberger

et al. 2017

JAD

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Abstract. Episodic memory tests with cued recall, such as the Free and Cued Selective Reminding Test (FCSRT), allow for the delineation of hippocampal and prefrontal atrophy contributions to memory performance in Alzheimer's disease (AD). Both Word and Picture versions of the test exist but show different profiles, with the Picture version usually scoring higher across different cohorts. One possible explanation for this divergent performance between the different modality versions of the test might be that they rely on different sets of neural correlates. The current study explores this by contrasting the neural correlates of the Word and Picture versions of the FCSRT with voxel-based morphometry (VBM) in AD and healthy subjects. We predicted that the Picture version would be associated with different cortical regions than the Word version, which might be more hippocampal-centric. When comparing 35 AD patients and 34 controls, AD patients exhibited impairments on both versions of the FCSRT and both groups performed higher in the Picture version. A region of interest analysis based on prior work revealed significant correlations between free recall of either version with atrophy of the temporal pole and hippocampal regions. Thus, contrary to expectations, performance on both the Word and the Picture version of the FCSRT is associated with largely overlapping networks. Free recall is associated with hippocampal volume and might be properly considered as an indicator of hippocampal structural integrity.

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“…Recientemente, se vienen n e u r o l a r g . 2 0 1 5;x x x(x x):xxx-xxx realizando estudios preliminares de validación de instrumentos diagnósticos de uso breve, que definen mejor la demencia y discriminan con mayor claridad los grados de severidad del deterioro cognitivo, como el Eurotest, el ACE-R, el IFS-Ch y el MIS [47][48][49][50] . En segundo lugar, el ruido ambiental y la interferencia asociada a una AF y cognitiva grupal.…”

Section: Discussionunclassified

Efectos de un programa combinado de actividad física y entrenamiento cognitivo en pacientes chilenos con Alzheimer leve

López

Burgos

Soto‐Añari

et al. 2015

Neurología Argentina

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Propiedades psicométricas y utilidad diagnóstica del Addenbrooke's Cognitive Examination-Revised (ACE-R) en una muestra de ancianos chilenos

Abstract: Background: The Addenbrooke's Cognitive Examination -Revised (ACE-R) is a good alternative to the Mini Mental State Examination (MMSE) for 822 with CDR), functional capacity assessments and r = 0,650 with IADL Scale) and a measure of cognitive changes (Rev Med Chile 2012; 140: 1006-1013.

Cited by 40 publications

References 27 publications

Chilean version of the INECO Frontal Screening (IFS-Ch): Psychometric properties and diagnostic accuracy

Chilean version of the INECO Frontal Screening (IFS-Ch): Psychometric properties and diagnostic accuracy

Neuroanatomical Comparison of the “Word” and “Picture” Versions of the Free and Cued Selective Reminding Test in Alzheimer’s Disease

Efectos de un programa combinado de actividad física y entrenamiento cognitivo en pacientes chilenos con Alzheimer leve

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