“…After removing duplicates, 1796 abstracts were screened and, from these, 193 full-text articles were assessed for eligibility. One study was published in Spanish 158 and all others were published in English. The flow of studies is presented in Figure 16.…”
Section: Resultsmentioning
confidence: 99%
“…176 Our exploration of a range of specific cognitive functions suggested no effect in memory, praxis, language or attention. 159 Hoffmann 2017 164 Holthoff 2015 165 Kemoun 2010 166 López 2015 158 Pitkälä 2013 168 Venturelli 2011 171 Venturelli 2016 172 Vreugdenhil 2012 148 Yang 2015 173 Subtotal (95% CI) Heterogeneity: τ 2 = 0.31; χ 2 = 46.10, df = 9 (p < 0.00001); I 2 = 80% Test for overall effect: z = 3.02 (p = 0.003) AD and non-AD Arcoverde 2014 160 Bossers 2015 161 Cheng 2014 162 DAPA trial Miu 2008 167 Underwood 2013 149 Subtotal (95% CI) Heterogeneity: τ 2 = 0.00; χ 2 = 4.99, df = 5 (p = 0.42); I 2 = 0% Test for overall effect: z = 0.08 (p = 0.94)…”
“…[158][159][160][161][162][163]165,167,169,170,172,173,DAPA RCT Eleven studies included participants with Alzheimer's disease only 148,158,159,[164][165][166]168,169,[171][172][173] and eight included various types of dementia, including Alzheimer's Disease, or did not report the disease type. 149,[160][161][162][163]167,170,DAPA RCT Participants were either recruited from community settings (9/19, 58%) 148,158,164,165,[167][168][169]173,DAPA RCT or nursing homes. Three studies (3/19, 16%) 164,165,172 had an upper-age restriction within their eligibility criteria, and for these studies the average age of participants ranged from 70 to 85 years.…”
Section: Economic Evaluationmentioning
confidence: 99%
“…160,163,164,166,167,[169][170][171][172][173] Seven studies used a mixed-resistance and aerobic exercise. 148,149,159,161,165,168,DAPA RCT One study used resistance exercise only 158 and one study used three-dimensional exercises (tai chi and yoga only). 162 The interventions varied in the mode of delivery.…”
This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full programme and will be published in full in Vol. 22, No. 28. See the NIHR Journals Library website for further project information. Additional funding was provided by the Oxford NIHR Biomedical Research Centre and the Oxford NIHR Collaboration for Leadership in Applied Health Research and Care.
“…After removing duplicates, 1796 abstracts were screened and, from these, 193 full-text articles were assessed for eligibility. One study was published in Spanish 158 and all others were published in English. The flow of studies is presented in Figure 16.…”
Section: Resultsmentioning
confidence: 99%
“…176 Our exploration of a range of specific cognitive functions suggested no effect in memory, praxis, language or attention. 159 Hoffmann 2017 164 Holthoff 2015 165 Kemoun 2010 166 López 2015 158 Pitkälä 2013 168 Venturelli 2011 171 Venturelli 2016 172 Vreugdenhil 2012 148 Yang 2015 173 Subtotal (95% CI) Heterogeneity: τ 2 = 0.31; χ 2 = 46.10, df = 9 (p < 0.00001); I 2 = 80% Test for overall effect: z = 3.02 (p = 0.003) AD and non-AD Arcoverde 2014 160 Bossers 2015 161 Cheng 2014 162 DAPA trial Miu 2008 167 Underwood 2013 149 Subtotal (95% CI) Heterogeneity: τ 2 = 0.00; χ 2 = 4.99, df = 5 (p = 0.42); I 2 = 0% Test for overall effect: z = 0.08 (p = 0.94)…”
“…[158][159][160][161][162][163]165,167,169,170,172,173,DAPA RCT Eleven studies included participants with Alzheimer's disease only 148,158,159,[164][165][166]168,169,[171][172][173] and eight included various types of dementia, including Alzheimer's Disease, or did not report the disease type. 149,[160][161][162][163]167,170,DAPA RCT Participants were either recruited from community settings (9/19, 58%) 148,158,164,165,[167][168][169]173,DAPA RCT or nursing homes. Three studies (3/19, 16%) 164,165,172 had an upper-age restriction within their eligibility criteria, and for these studies the average age of participants ranged from 70 to 85 years.…”
Section: Economic Evaluationmentioning
confidence: 99%
“…160,163,164,166,167,[169][170][171][172][173] Seven studies used a mixed-resistance and aerobic exercise. 148,149,159,161,165,168,DAPA RCT One study used resistance exercise only 158 and one study used three-dimensional exercises (tai chi and yoga only). 162 The interventions varied in the mode of delivery.…”
This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full programme and will be published in full in Vol. 22, No. 28. See the NIHR Journals Library website for further project information. Additional funding was provided by the Oxford NIHR Biomedical Research Centre and the Oxford NIHR Collaboration for Leadership in Applied Health Research and Care.
Introduction: Early-life educational experiences are associated with cognitive performance in aging. Early literacy seems to improve executive control mechanisms, however, it is not clear whether early education would still be an advantage in countries like Peru, where access to and quality of education is highly variable.Aim: Our objective was to analyze the association of literacy level with executive control factors.Method: We evaluated 93 healthy older adults with a clinical protocol that included the Mini-Mental State Examination, the Geriatric Depression Scale and Global Dementia Staging. We also used a neuropsychological executive function battery which included the Trail-Making Test parts A and B, the Stroop Test, phonological and semantic verbal fluency tasks, Forward and Backward Digits, Numbers and Letters of the Wechsler Scale, and the Go/No-Go task. We used a principal component analysis for the dimensional reduction of the variables. To measure the level of literacy we used the word accentuation test (WAT).Results: We observed statistically significant correlations between the principal components (PCs) of working memory, cognitive flexibility and inhibitory control with the WAT scores. Furthermore, we observed that processing speed and WAT predict the scores on PCs factors better than years of education and age.Conclusions: Literacy level correlates more closely with better cognitive performance than years of education and thus, might improve executive control factors that could compensate and protect against brain changes in cognitive decline and dementia.
Aim: To characterize physical exercise programs for older adults in Latin America. Methods: This review was conducted in accordance with the PRISMA statement. A search for randomized controlled trials (RCTs) published between the years 2015 and 2020 was performed in the Scopus, MedLine and SciELO databases. Results: A total of 101 RCTs were included. A large percentage of the studies had an unclear risk of bias in the items: selection, performance, detection and attribution. Furthermore, a heterogeneous level of compliance was observed in the CERT items. A total sample of 5013 older adults (79% women) was included. 97% of the studies included older adults between 60–70 years, presenting an adherence to the interventions of 86%. The studies were mainly carried out in older adults with cardiometabolic diseases. Only 44% of the studies detailed information regarding the place of intervention; of these studies, 61% developed their interventions in university facilities. The interventions were mainly based on therapeutic physical exercise (89% of the articles), with a duration of 2–6 months (95% of the articles) and a frequency of 2–3 times a week (95% of the articles) with sessions of 30–60 min (94% of the articles) led by sports science professionals (51% of the articles). The components of physical fitness that were exercised the most were muscular strength (77% of the articles) and cardiorespiratory fitness (47% of the articles). Furthermore, only 48% of the studies included a warm-up stage and 34% of the studies included a cool-down stage. Conclusions: This systematic review characterized the physical exercise programs in older adults in Latin America, as well the most frequently used outcome measures and instruments, by summarizing available evidence derived from RCTs. The results will be useful for prescribing future physical exercise programs in older adults.
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