Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis of 25 years of research

Meijer, Anna; Conradi, Henk Jan; Bos, Elisabeth H.; Thombs, Brett D.; Melle, Joost P. van; Jonge, Peter de

doi:10.1016/j.genhosppsych.2011.02.007

Cited by 450 publications

(346 citation statements)

References 39 publications

Supporting

Mentioning

298

Contrasting

Unclassified

Order By: Relevance

“…In addition, our findings are also in line with meta-analyses that showed that depressive symptoms following MI are a stronger predictor of mortality than cardiovascular events [Meijer et al, 2011;Meijer et al, 2013a], suggesting that the potential effect of depression on medical illness is not specific for heart disease. On the other hand, it could also be that depressive symptoms are only predictive of specific events, such as (acute) ischemic events, or that only specific depressive symptoms, excluded from our study, are related to non-fatal cardiac events, or that depressive symptoms are predictive of non-fatal cardiovascular events at short-term but not at long-term follow-up.…”

Section: Discussionsupporting

confidence: 90%

Symptom and course heterogeneity of depressive symptoms and prognosis following myocardial infarction.

Roest¹,

Wardenaar²,

Jonge³

2016

Health Psychology

Self Cite

View full text Add to dashboard Cite

Objective: Previously published findings from the DepreMI cohort suggested that both the course and the type of depressive symptoms following myocardial infarction (MI) are related to prognosis, but did not examine both factors simultaneously. The aim of this re-analysis study was to assess whether MI patients can be empirically classified based on trajectories of cognitive/affective (CA) and somatic/affective (SA) symptoms, and whether these classes differentially predict adverse outcomes. Results: Three classes were identified: 'low severity': consistently low CA and SA (n=316); 'somatic persistence': consistently low CA and high SA (n=110); and 'overall persistence': high and increasing CA and SA (n=31). After adjustment for gender and the Global Registry of Acute Coronary Events risk score, somatic persistence (HR:1.86; 95% CI: 1.18-2.94; p=0.008), but not overall persistence (HR:1.09.; 95% CI: 0.39-3.03; p=0.87), predicted mortality compared with low severity. Classes were not predictive of non-fatal cardiovascular events.Conclusions: MI patient classes differed in severity and course of CA and SA depressive symptoms in the post-MI year. Only a class with persistent SA depressive symptoms was associated with increased mortality compared with patients with low severity. This is suggestive of different origins of SA depressive symptoms in MI patients that may explain the differential associations with mortality.

show abstract

Section: Discussionsupporting

confidence: 90%

Symptom and course heterogeneity of depressive symptoms and prognosis following myocardial infarction.

Roest¹,

Wardenaar²,

Jonge³

2016

Health Psychology

Self Cite

View full text Add to dashboard Cite

show abstract

“…The relevance of the presence of anxiety and depression in cardiac patients has repeatedly been shown in systematic reviews; both are associated with higher death rates and poorer prognoses in general in cardiovascular disease (3)(4)(5).…”

mentioning

confidence: 89%

Revisiting the dimensionality of the Hospital Anxiety and Depression Scale in an international sample of patients with ischaemic heart disease

Burns

Höfer

Curry

et al. 2014

Journal of Psychosomatic Research

View full text Add to dashboard Cite

“…Its prevalence ranges from 6.6% to 21% across countries (Kessler and Bromet, 2013), rising to 18.3% in Qatar (Bener et al, 2015). Nearly 20% of patients with heart disease suffer from depression (Carney and Freedland, 2008;Elderon and Whooley, 2013;Thombs et al, 2006), while depression following myocardial infarction is associated with 2.25-to 2.38-fold risk of all-cause mortality and 2.59-to 2.71-fold risk of cardiac mortality (Meijer et al, 2011;van Melle et al, 2004). In patients with heart failure, depression is associated with 51% increased risk of all-cause mortality and 119% increased risk of cardiac mortality (Fan et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Translation and validation of the Cardiac Depression Scale to Arabic

Papasavvas

Al-Amin

Ghabrash

et al. 2016

Asian Journal of Psychiatry

View full text Add to dashboard Cite

Background: The Cardiac Depression Scale (CDS) has been designed to measure depressive symptoms in patients with heart disease. There is no Arabic version of the CDS. We translated and validated the CDS in an Arabic sample of patients with heart disease. Methods: Forward and back translation of the CDS was followed by assessment of cultural relevance and content validity. The Arabic version of the CDS (A-CDS) and the Arabic version of the Hospital Anxiety and Depression Scale (A-HADS) were then administered to 260 Arab in-patients with heart disease from 18 Arabic countries. Construct validity was assessed using exploratory factor analysis with polychoric correlations. Internal consistency was assessed using ordinal reliability alpha and item-to-factor polychoric correlations. Concurrent validity was assessed using Pearson's correlation coefficient between the A-CDS and the depression subscale of the A-HADS (A-HADS-D).Results: Cultural relevance and content validity of the A-CDS were satisfactory. Exploratory factor analysis revealed three robust factors, without cross-loadings, that formed a single dimension. Internal consistency was high (ordinal reliability alpha for the total scale and the three factors were .94, .91, .86, and .87, respectively; item-to-factor correlations ranged from .77 to .91). Concurrent validity was high (r = .72). The A-CDS demonstrated a closer to normal distribution of scores than the A-HADS-D. Limitations: Sensitivity and specificity of the A-CDS were not objectively assessed. Conclusions: The A-CDS appears to be a valid and reliable instrument to measure depressive symptoms in a representative sample of Arab in-patients with heart disease.Keywords: Arabic; Cardiac Depression Scale; cultural relevance; depression; heart disease; scale validation Highlights• We translated and validated the Cardiac Depression Scale to Arabic.• Cultural relevance and content validity were satisfactory.• A stable, parsimonious, and meaningful three-factor model was created.• Internal consistency and concurrent validity were high.• The translated scale appears to be a valid and reliable instrument.

show abstract

Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis of 25 years of research

Abstract: Post-MI depression is associated with a 1.6- to 2.7-fold increased risk of impaired outcomes within 24 months. This association has been relatively stable over the past 25 years.

Cited by 450 publications

References 39 publications

Symptom and course heterogeneity of depressive symptoms and prognosis following myocardial infarction.

Symptom and course heterogeneity of depressive symptoms and prognosis following myocardial infarction.

Revisiting the dimensionality of the Hospital Anxiety and Depression Scale in an international sample of patients with ischaemic heart disease

Translation and validation of the Cardiac Depression Scale to Arabic

Contact Info

Product

Resources

About