Prions and neuronal death

Apoptosis, a genetically regulated form of cell death with distinct biochemical and morphological features, plays a relevant physiological and pathological role in the organism, being pivotal in the maintenance of tissue development and homeostasis in the adult as well as in the regulation of immune responses. Deregulation of this process causes several human disorders including cancer, autoimmune and neurodegenerative diseases. Thus, modulation of the apoptotic process and of cell death in general, is a potential therapeutic approach for the treatment of several human pathologies.

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Cell death in disease: from 2010 onwards

Knight

Melino

2011

Cell Death Dis

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The strong interest in cell death, and the shift in emphasis from basic mechanisms to translational aspects fostered the launch last year of the new sister journal of Cell Death and Differentiation, named Cell Death and Disease, to reflect its stronger focus towards clinical applications. Here, we review that first year of activity, which reflects an enthusiastic response by the scientific community. On the basis of this, we now launch two novel initiatives, the start of a new section dedicated to cancer metabolism and the opening of a new editorial office in Shanghai.

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Prions and neuronal death

Abstract: The present contribution is a Letter to the Editor (Correspondence) and, as a consequence, no abstract is available.[...

Cited by 4 publications

References 4 publications

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Cell death pathology: Perspective for human diseases

Cell death in disease: from 2010 onwards

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