Prevalence of urinary tract infection among children

Almofarreh, Moatez Khalaf; Alowaa, Zainab; Junainah, Elaf; Alshahrani, Nourah Falah; Alharbi, Meshal; Alkhalifah, Waleed; Aldmak, Amer Farhan; Salawi, Mohammed; Alaradi, Abdullah; Althomali, Ruya Abdulaziz

doi:10.18203/2349-3291.ijcp20183878

Cited by 9 publications

(11 citation statements)

References 17 publications

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“…The guideline recommends that the choice of agent is also based on local antimicrobial sensitivity patterns and should later be adjusted according to sensitivity-testing of the isolated uropathogen. Frequently used antibacterial substances for UTI therapy in infants and children were cephalosporins, trimethoprim or trimethoprim/sulfamethoxazole, ampicillin, amoxicillin, amoxicillin/clavulanic acid, tobramycin, gentamicin, ciprofloxacin, and nitrofurantoin [8]. Our investigation also found a similar pattern of etiological uropathogens and antibacterial agents, with some uropathogen heterogeneity and antibacterial resistance.…”

Section: Discussionsupporting

confidence: 71%

Retrospective Analysis of Antimicrobial Susceptibility of Uropathogens Isolated from Pediatric Patients in Tertiary Hospital at Al-Baha Region, Saudi Arabia

et al. 2021

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Introduction: Prompt diagnosis and initiation of treatment are essential in preventing long-term renal scarring. However, increasing antibiotic resistance may delay the initiation of appropriate therapy. Methodology: A retrospective chart review was performed for patients admitted to the pediatric department with urinary tract infection (UTI) diagnosis in a large tertiary care hospital in Al Baha, Saudi Arabia, from May 2017 to April 2018. The study included children of both sexes under the age of 14 years. Results: Out of 118 urinary bacterial samples, Escherichia coli was the main etiologic agent in the community- and hospital-acquired infections. The infection rate was higher in girls (68.64%) than in boys (31.36%). The commonest isolates were Escherichia coli (44.07%), extended-spectrum beta-lactamase-producing Escherichia coli (11.86%), Klebsiella pneumoniae (9.32%), Enterococcus faecalis (7.63%), methicillin-resistant Staphylococcus epidermidis (4.24%), and coagulase-negative Staphylococci (3.39%). The current study demonstrates that nitrofurantoin (19%) was the most commonly prescribed medication in the inpatient and outpatient departments, followed by trimethoprim/sulfamethoxazole (16%), amoxicillin/clavulanic acid (15%), cefuroxime (10%), azithromycin (8%), ceftriaxone (7%), and ciprofloxacin (4%), while amikacin, amoxicillin, ampicillin, cefepime, imipenem, phenoxymethylpenicillin were prescribed less commonly due to the high resistance rate. Conclusion: The microbial culture and sensitivity of the isolates from urine samples should be routine before starting antimicrobial therapy. Current knowledge of the antibiotic susceptibility patterns of uropathogens in specific geographical locations is essential for choosing an appropriate empirical antimicrobial treatment rather than reliance on recommended guidelines.

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Section: Discussionsupporting

confidence: 71%

Retrospective Analysis of Antimicrobial Susceptibility of Uropathogens Isolated from Pediatric Patients in Tertiary Hospital at Al-Baha Region, Saudi Arabia

et al. 2021

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“…This prevalence is comparable to many studies Shaikh N et al, [8] and Bauchner et al [9], showed prevalence range from 1.2% to 8%. As per Almofarreh M et al study, gender is the commonest influencing factor of UTI [10]; the studies also reported that the prevalence of UTI is more in female children [11,12,13]. The anatomical structure as well as less distance with anal region is the main reported cause for more prevalence of UTI among female children.…”

Section: Discussionmentioning

confidence: 76%

Prevalence of urinary tract infection in febrile children between one to five years of age

Sriram¹,

Satyanarayana²,

Naik³

et al. 2019

Int J Pediatr Res

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Introduction: It is essential to identify urinary tract infection (UTI) in febrile children and institute prompt treatment to reduce the potential for lifelong morbidity. With this a study was taken to find the prevalence of UTI in febrile children one year to five years of age. Materials and Methods: Study was conducted in GSL Medical College. Febrile children aged 1 year to 5 years attending the outpatient department or admitted in the hospital were included in the study. Socioeconomic status was categorized as per modified kuppuswamy scale. The fresh urine sample was subjected for urinalysis and culture and sensitivity. Chi-square test was used to assess the association between different categorical variables; P<0.05 was considered statistically significant. Results: Total 200 participants were included with male female ratio 0.87. Maximum cases were in lower middle class and nil participants in upper class. Significant pyemia was detected 13.5% (27) cases, statistically the difference was not significant (P>0.05) and culture positivity was 8% (16); Esch. coli was the predominant pathogen, followed by Klebsiella pneumoniae, Pseudomonas aeruginosa and serratia spp. Conclusion: The culture positivity was 8% which is significant in the pediatric group. Hence any child with fever, UTI also should be suspected.

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“…2 The risk of infection can be augmented in certain conditions, such as age under 3 months, uncircumcised males, malnutrition, and constipation. 3 The prevalence of urinary tract infections in children by antibiotic-resistant bacteria has been reported in many studies. For instance, Nazmi et al, revealed that an overall prevalence of UTI caused by ESBL Escherichia coli and Klebsiella pneumoniae were 35% and 45%, respectively, in a private hospital in Tangerang.…”

Section: Introductionmentioning

confidence: 99%

The Characteristics of Children with UTI Due to ESBL-producing Bacteria at Dr. Soetomo General Hospital, Surabaya

Fitriawati

Wahyunitisari

Prasetyo

et al. 2021

BHSJ

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Introduction: Urinary tract infection (UTI) by extended-spectrum beta-lactamase-producing bacteria often results in a delay in obtaining appropriate antibiotics. The information on patients’ clinical characteristics is necessary for early recognition and the selection of empiric antibiotic therapy. This study aims to investigate the clinical characteristics and the length of therapy of patients with urinary tract infections by those resistant bacteria.Method: This study utilizes a cross-sectional design. Medical records of hospitalized children aged 1-18 months with UTI due to ESBL-producing bacteria at Dr. Soetomo general hospital between January 1, 2017 - July 20, 2020, were reviewed retrospectively. Variables of interest were the demographic data, underlying diseases, causative organism, clinical presentation, maximal body temperature, and length of antibiotic therapy.Results: Among 37 patients enrolled, 25 patients were female. The incidence of urinary tract infection in children was dominated by age 1-12 months old (37.8%). Urological abnormalities were presented in 62.2% of patients. ESBL-producing Escherichia coli was the most common isolated uropathogen (62.2%). High fever was found in 10/28 patients (35.7%). In 17 patients (45.9%), the total duration of antibiotic therapy was 8-14 days.Conclusion: In children with UTI, especially in the infant group, who had urological abnormality or present with a high fever, and who do not respond to empiric therapy should be suspected of developing UTI due to ESBL-producing bacteria.

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Prevalence of urinary tract infection among children

Cited by 9 publications

References 17 publications

Retrospective Analysis of Antimicrobial Susceptibility of Uropathogens Isolated from Pediatric Patients in Tertiary Hospital at Al-Baha Region, Saudi Arabia

Retrospective Analysis of Antimicrobial Susceptibility of Uropathogens Isolated from Pediatric Patients in Tertiary Hospital at Al-Baha Region, Saudi Arabia

Prevalence of urinary tract infection in febrile children between one to five years of age

The Characteristics of Children with UTI Due to ESBL-producing Bacteria at Dr. Soetomo General Hospital, Surabaya

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