2015
DOI: 10.17795/jjhr-23831
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Prevalence, Demographics and Clinical Characteristics of Multiple Sclerosis in North of Khuzestan Province, Iran

Abstract: Background: Multiple sclerosis (MS) is a chronic, idiopathic and the most common inflammatory demyelinating disease of the central nervous system that progresses to severe disability. Prevalence of MS is 2-150 per 100,000 people. The main cause of the disease is not clear and occurs due to a combination of both genetic and environmental factors. Objectives: The purpose of this study was to determine the prevalence rate of MS in the northern cities of Khuzestan Province, Iran, as well as to determine the demogr… Show more

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Cited by 11 publications
(16 citation statements)
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References 25 publications
(37 reference statements)
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“…This finding indicated that the incidence rate of familial MS was low in the sample being studied, namely the population in Hamadan society. This result was similar to previous studies where MS was more common in women than in men (18,22). In addition, our result confirmed that healthcare and support services have improved compared to past years (including increased numbers of neurologists and MRIs) (12).…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…This finding indicated that the incidence rate of familial MS was low in the sample being studied, namely the population in Hamadan society. This result was similar to previous studies where MS was more common in women than in men (18,22). In addition, our result confirmed that healthcare and support services have improved compared to past years (including increased numbers of neurologists and MRIs) (12).…”
Section: Discussionsupporting
confidence: 92%
“…However, it has been shown that there has been an increase in the prevalence of MS between 2008 (1) and 2013 (5,12,21,22). It has also been reported that 5% -13% of MS patients have an affected relative (23)(24)(25)(26)(27).…”
Section: Introductionmentioning
confidence: 99%
“…Recent investigations showed that the prevalence of MS in Iran increased significantly (12) and it was 45/100,000 individuals (in 2011) (13). In the recent studies, the prevalence of MS in Khuzestan province, South-West of Iran, was 15 -18.50 per 100,000 people (14,15). The clinical studies described 4 types of MS: 1) About 85% of the affected patients are diagnosed with relapsing-remitting (RRMS) type of MS, a relapse phase followed by remission phase (16); 2) The second most frequent type of MS is secondary progressive MS (SPMS) that occurs in about 30% of the patients (1); 3) The third type of MS that affects 10% -15% of people with MS is called primary progressive MS (PPMS) (17); 4) Progressiverelapsing MS (PRMS) occurs in 5% of cases and has overlap with PPMS and SPMS (7).…”
Section: Introductionmentioning
confidence: 98%
“…If this type develops to progressive neurological relapse between the attacks, the MS subtypes is SP subtype. The PP subtype, which is more common among older men, is characterized by no remission after the initial symptoms …”
Section: Introductionmentioning
confidence: 99%
“…It is believed that the type of initial symptoms affects the disease prognosis; for example, sensory symptoms will be diagnosed more easily than cerebellar or motor involvement at the beginning of the disease . In contrast, clinical manifestation of MS might differ geographically.…”
Section: Introductionmentioning
confidence: 99%