Background: Multiple sclerosis (MS) is a chronic, idiopathic and the most common inflammatory demyelinating disease of the central nervous system that progresses to severe disability. Prevalence of MS is 2-150 per 100,000 people. The main cause of the disease is not clear and occurs due to a combination of both genetic and environmental factors. Objectives: The purpose of this study was to determine the prevalence rate of MS in the northern cities of Khuzestan Province, Iran, as well as to determine the demographic characteristics, initial symptoms at onset, clinical features and the correlation between the above factors with each other. Patients and Methods: In this descriptive correlational study, patients were recruited through the MS Society as well as the neurology clinics and departments of hospitals in north cities of Khuzestan Province (Iran). Data were collected through completing a face to face questionnaire and were analyzed using SPSS version 17 and the chi-square test. P value < 0.05 was considered statistically significance. Results: A total of 142 patients were participated in this study. Prevalence of MS was 15 per 100,000 people. Seventy-eight percent of the patients had low literacy, and 81% were unemployed. Female to male ratio was 2.08: 1 that became less in younger patients. 69% and 15% of the patients were relapsing remitting and progressive relapsing, respectively. Demographic characteristics of the patients did not show any statistically significant relationship with clinical courses and signs at onset; however, a significant correlation was seen between severe disability and sex (P = 0.001) as well as between severe disability and progressive-relapsing subtype (P = 0.02). Conclusions: The prevalence of MS showed an increasing rate of the disease in recent years. Decreasing of the female to male ratio and patients' low socioeconomic level, need more studies. The increasing rate of patients with progressive relapsing feature and more disabled patients belong to this subtype show the poor prognosis.
We present a patient with unstable angina candidate for coronary artery bypass grafting. Saphenous vein graft was used in obtuse marginal and left internal mammary artery to left anterior descending artery properly. After surgery, the patient experienced flaccid paralysis of lower limb and impaired sensation of touch and warmth of knee and below. A computed tomography angiogram of lower limbs and thoracolumbar magnetic resonance imaging showed no abnormality. Based on the symptom, clinical diagnosis of anterior spinal artery syndrome was considered. The artery of Adamkiewicz is an important supplier to the anterior spinal artery. Internal thoracic mammary artery, used in coronary artery bypass grafting, is suspected as a collateral supplier of the artery of Adamkiewicz and has been accused for cause of spinal infarction.
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