Prevalence and epidemiological and histopathological features of canine cutaneous mast cell tumours in Uberlândia, Brazil

Costa, Marcelo Carrijo da; Silva, Ana Letícia Daher Aprígio; Moreira, Thaís de Almeida; Gundim, Lígia Fernandes; Medeiros-Ronchi, Alessandra Aparecida

doi:10.2754/avb201786020189

Cited by 3 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…According to Merlo et al (31), the critical period to cancer onset in dogs is 6 to 10 years old. This suggests that older ages predispose dogs to develop neoplasms, this was also reported by many authors Kaldrymidou et al; Costa et al; Hargis et al (18,30,32). However, in the present study, only two cases were reported in dogs less than one year of age.…”

Section: Discussionsupporting

confidence: 75%

See 1 more Smart Citation

Incidence of cutaneous and subcutaneous tumors of dogs from Baghdad city: Clinical, cytological and histopathological features

Lafta¹,

Alabbody²

2020

IJVS

View full text Add to dashboard Cite

The present study was conducted to estimate the incidence, clinical findings, cytological and histopathological characteristics of spontaneously occurring skin neoplasms in dogs. A total of 40 grossly suspected cases of cutaneous and subcutaneous tumors were gathered during the period from July 2016 to August 2018 from male and female dogs in Baghdad city. Dogs with skin neoplasia revealed various clinical signs, and their ages were older than 5 years to 15 years. German shepherd 30% followed by Terrier dogs 25% were more influenced than other breeds. Concerning tumor features, the majority of neoplasms had solitary lesion 70%, regular shapes 65% with black color 55%. The tumors frequently occurred on fore-limbs and abdomen, and 80% of them lasted for 1-6 months. Cytological examination was valuable for initial evaluation of benign and malignant tumors. Its results were confirmed by the histopathology, in which the majority of neoplasms sized more than 5 cm and grade I. Nine different types of skin neoplasms were recognized, while 65% of them were malignant, the others were benign. Squamous cell carcinoma and adenocarcinomas were the most common comprising 35% and 25%, respectively.

show abstract

Section: Discussionsupporting

confidence: 75%

“…These injuries, e.g. necrosis, edema, and hemorrhage are not statistically correlated with histological classification of tumors (30). In this study, skin tumors were mainly reported in older dogs.…”

Section: Discussionmentioning

confidence: 56%

Incidence of cutaneous and subcutaneous tumors of dogs from Baghdad city: Clinical, cytological and histopathological features

Lafta¹,

Alabbody²

2020

IJVS

View full text Add to dashboard Cite

show abstract

“…Analisou-se a relação entre a idade dos animais acometidos por mastocitomas e a graduação dos tumores e foi possível observar que animais acima de 6 anos apresentaram maior número de tumores Grau III (Quadro 2). De Carvalho et al (2017) relatam que a classificação histológica é dependente da idade, sendo que os cães idosos têm 8 vezes mais chances de terem tumores classificados em alto grau.…”

Section: Resultsunclassified

“…Dentre as principais neoplasias que ocorrem nos animais domésticos, destacam-se as neoplasias de pele e dentre essas, o mastocitoma. Na região de Uberlândia, o mastocitoma e o carcinoma de células escamosas são as neoplasias de pele mais frequentes (COSTA et al, 2017).…”

Section: Introductionunclassified

See 1 more Smart Citation

Estudo Retrospectivo Do Mastocitoma Cutâneo Canino E Papel Do Azul De Toluidina Na Graduação Histológica De Mastocitomas

Medeiros-Ronchi¹,

Souza²,

Oliveira³

et al. 2018

Enci Bio

View full text Add to dashboard Cite

RESUMO O mastocitoma é uma das neoplasias de pele mais comuns em cães. A partir da análise histológica destes tumores, obtêm-se a graduação histológica, porém há grande divergência entre os patologistas na classificação de grau II. Objetivou-se verificar se a coloração de azul de toluidina (AT) auxilia a classificação de mastocitomas grau II e realizar estudo epidemiológico e clínicopatológico de mastocitomas cutâneos caninos atendidos no Hospital Veterinário da Universidade Federal de Uberlândia. Foram analisados 85 cães, sendo 71% fêmeas e 29% machos. Os cães mestiços foram mais frequentemente afetados (44%) e as faixas etárias entre 6 a 10 anos e 11-15 anos foram as mais frequentes (p,0,05). Analisando a relação entre idade e graduação, notou-se que animais acima de 6 anos apresentaram mais tumores Grau I. Macroscopicamente, os tumores eram predominantemente nodulares (71,8%), brancacentos (45,9%), 30,6 eram aderidos, 51,8% não eram ulcerados e 50,6% mediam menos que 5 cm. As localizações mais frequentes foram o tronco (34,1%) e a região inguinal (17,6%). Na graduação histológica, quando classificados em três graus, a maioria das neoplasias foram classificadas como grau II e quando classificadas em dois graus, 65,9% foram graduados como de baixo grau e 31,8% como alto grau. Dos 40 tumores classificados como grau II, 27,5% foram reclassificados como grau I na coloração especial de AT e 10% como grau III. Conclui-se que a graduação histológica influencia no aspecto macroscópico dos mastocitomas e na ulceração. A coloração de azul de toluidina pode ser utilizada na otimização da avaliação de mastocitomas grau II. PALAVRAS-CHAVE: cão, coloração especial.Mastócitos, neoplasia.

show abstract

Cytological grading of canine mast cell tumors: correlation with histologic grading and survival time

et al. 2023

View full text Add to dashboard Cite

Mast cell tumors are one of the most common neoplasia in dogs and cytopathology and/or histopathology examinations are used for diagnosis. Histologic grading is considered the gold standard test to predict the prognosis of this neoplasia. However, studies have been conducted using the cytological grading system to provide similar information in a faster, less invasive, and more accessible way. This study aimed to investigate cytological graduation and correlate it with histological grading and the survival time of dogs diagnosed with cutaneous mast cell tumors at the Veterinary Hospital of “Universidade Federal de Uberlândia” over five years. For that, cytological and histological slides from 72 animals were reviewed. The statistical methods used were the kappa test for agreement between grading systems, the Kaplan-Meier for survival time, Cox regression for comparison of cytological and histological grades and survival time. The cytological grading when compared to the two-tier histologic grading, high and low grades, had a moderate agreement (kappa 0.566). When the correlation between survival time and the cytological grade was evaluated, there was a higher death rate in the group with high-grade mast cell tumors compared to low grade, pointing to a correlation between survival time and cytological grade (p=0.009). In conclusion, the cytological grade is useful to treatment planning and providing prognostic information that precedes tumor removal, showing a good correlation with the two-tier histologic grading and with the survival time of the animals.

show abstract

Prevalence and epidemiological and histopathological features of canine cutaneous mast cell tumours in Uberlândia, Brazil

Cited by 3 publications

References 9 publications

Incidence of cutaneous and subcutaneous tumors of dogs from Baghdad city: Clinical, cytological and histopathological features

Incidence of cutaneous and subcutaneous tumors of dogs from Baghdad city: Clinical, cytological and histopathological features

Estudo Retrospectivo Do Mastocitoma Cutâneo Canino E Papel Do Azul De Toluidina Na Graduação Histológica De Mastocitomas

Cytological grading of canine mast cell tumors: correlation with histologic grading and survival time

Contact Info

Product

Resources

About