Preparation of silver nanoparticles with antimicrobial activities and the researches of their biocompatibilities

Cao, Xuelian; Cheng, Chong; L, Dr. Yesappa; Zhao, Changsheng

doi:10.1007/s10856-010-4133-2

Cited by 151 publications

(102 citation statements)

References 30 publications

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“…The authors suggested that the difference in MIC values could be related to the variation in nanoparticle size and shape. Silver/chitosan nanocomposites were characterized by Cao et al [122] in terms of their particle sizes and morphology. The antibacterial activities of these nanocomposites against S. aureus and E. coli were investigated.…”

Section: Influence Of the Preparation Techniques Of Chitin/chitosan-bmentioning

confidence: 99%

Biomedical Activity of Chitin/Chitosan Based Materials—Influence of Physicochemical Properties Apart from Molecular Weight and Degree of N-Acetylation

et al. 2011

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Abstract:The physicochemical nature of chitin and chitosan, which influences the biomedical activity of these compounds, is strongly related to the source of chitin and the conditions of the chitin/chitosan production process. Apart from widely described key factors such as weight-averaged molecular weight (M W ) and degree of N-acetylation (DA), other physicochemical parameters like polydispersity (M W /M N ), crystallinity or the pattern of acetylation (P A ) have to be taken into consideration. From the biological point of view, these parameters affect a very important factor-the solubility of chitin and chitosan in water and organic solvents. The physicochemical properties of chitosan solutions can be controlled by manipulating solution conditions (temperature, pH, ionic strength, concentration, solvent). The degree of substitution of the hydroxyl and the amino groups or the degree of quaternization of the amino groups also influence the mechanical and biological properties of chitosan samples. Finally, a considerable research effort has been directed towards developing safe and efficient chitin/chitosan-based products because many factors, like the size of nanoparticles, can determine the biomedical characteristics of medicinal products. The influence of these factors on the biomedical activity of chitin/chitosan-based products is presented in this report in more detail. OPEN ACCESSPolymers 2011, 3 1876

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Section: Influence Of the Preparation Techniques Of Chitin/chitosan-bmentioning

confidence: 99%

Biomedical Activity of Chitin/Chitosan Based Materials—Influence of Physicochemical Properties Apart from Molecular Weight and Degree of N-Acetylation

et al. 2011

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“…15,22 These studies showed potential antibacterial activity against both Gram-negative and Gram-positive bacteria. 14,19,[23][24][25] Any metal nanoparticle could be evaluated for antiviral activity; however, little effort has already been devoted to the determination of nanoparticle's antiviral activity and their interactions with viruses.…”

Section: Introductionmentioning

confidence: 99%

Antiviral activity of mycosynthesized silver nanoparticles against herpes simplex virus and human parainfluenza virus type 3

Gaikwad¹,

Ingle²,

Gade³

et al. 2013

IJN

170

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The interaction between silver nanoparticles and viruses is attracting great interest due to the potential antiviral activity of these particles, and is the subject of much research effort in the treatment of infectious diseases. In this work, we demonstrate that silver nanoparticles undergo a size-dependent interaction with herpes simplex virus types 1 and 2 and with human parainfluenza virus type 3. We show that production of silver nanoparticles from different fungi is feasible, and their antiviral activity is dependent on the production system used. Silver nanoparticles are capable of reducing viral infectivity, probably by blocking interaction of the virus with the cell, which might depend on the size and zeta potential of the silver nanoparticles. Smaller-sized nanoparticles were able to inhibit the infectivity of the viruses analyzed.

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“…In recent years, Ag-NPs have been widely used in various applications because of their well-known effectiveness in biomedical (Cao et al, 2010), electronic, catalysis and optical applications (Hayward et al, 2000). In particular, the outstanding antimicrobial properties of AgNPs have led to the development of variety of silver nanoparticle products including nanosilver-coated bandages, surgical instruments, contraceptive devices and dental implants (Lohse et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Potential antibacterial activity of crude extracts and silver nanoparticles synthesized from Sargassum wightii

Thirumalairaj¹,

Vijayan²,

Durairaj³

et al. 2014

Int Curr Pharm J

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The present work investigates the antibacterial activity of silver nanoparticles (Ag-NPs) synthesized by biological method using Sargassum wightii. The fresh live seaweed was collected from the Mandapam coast of Tamilnadu, India. Solvent extract was prepared using acetone, petroleum ether and methanol. Aqueous extract of the seaweed was also used for the synthesis of silver Ag-NPs. Seaweed extract is used as a reducing agent of 2mM silver nitrate solution for the synthesis of Ag-NPs. Periodical monitoring of reaction mixture was done using UV-vis spectroscopy at 300-750 nm. The scanning electron microscopy (SEM) of the sample confirms the presence of Ag-NPs. The antibacterial activity of solvent extract was done by Minimal inhibitory concentration (MIC) assay. The methanol extract of the seaweed at a concentration of 250µg/ml exhibited potent antimicrobial activity against the test microorganism. The zone of inhibition ranging from 8-14 mm was observed with different extracts. The antibacterial activity of the synthesized Ag-NPs against the organism was also done by MIC test. The MIC of Ag-NPs was found to be 130µg/ml for all pathogenic microorganisms selected for the study. The zone of inhibition against Bacillus cereus, Bacillus anhtracis, Staphylococcus aureus and Vibrio alginoyticus were found to be 10, 8, 10 and 9 mm, respectively. The synthesized Ag-NPs exhibited significant antimicrobial activity against the selected microorganisms than the solvent extract of seaweed.DOI: http://dx.doi.org/10.3329/icpj.v3i10.20337 International Current Pharmaceutical Journal, September 2014, 3(10): 322-325

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Preparation of silver nanoparticles with antimicrobial activities and the researches of their biocompatibilities

Cited by 151 publications

References 30 publications

Biomedical Activity of Chitin/Chitosan Based Materials—Influence of Physicochemical Properties Apart from Molecular Weight and Degree of N-Acetylation

Biomedical Activity of Chitin/Chitosan Based Materials—Influence of Physicochemical Properties Apart from Molecular Weight and Degree of N-Acetylation

Antiviral activity of mycosynthesized silver nanoparticles against herpes simplex virus and human parainfluenza virus type 3

Potential antibacterial activity of crude extracts and silver nanoparticles synthesized from Sargassum wightii

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