Practical investigation of direct analysis in real time mass spectrometry for fast screening of explosives

Plasma‐based ambient mass spectrometry: Recent progress and applications

“…Using this approach, they achieved precise characterization of various energetic formulations of 83 preand postblast samples. Frazier et al (2020) summarized the advantages and limitations of several different DART-MS modules (QuickStrip, transmission, and closed mesh method, thermal desorption method, and direct-insert method) for detecting organic explosive residues, while another research group performed a comparative study of thermal desorption (TD)-DART-MS with helium and conventional DART-MS with three different discharge gas (helium, nitrogen, and argon) by analyzing 14 explosives . Forbes et al (2017) introduced a Joule heating thermal desorption (JHTD)-DART-MS to enhance the analysis ability of inorganic explosive than conventional DART-MS. Based on JHTD-DART, they developed a modified infrared thermal desorption (IRTD)-DART-MS , providing an effective method for the desorption and detection of organic explosives, including the species that were hard to detect using traditional DART-MS, and inorganic oxidizers at tens of nanograms sensitivities (Figure 5A).…”

Interpol review of the analysis and detection of explosives and explosives residues

“…DART-MS is primarily a fast technique wherein it's use as a sample screening tool is theoretically very useful. Frazier, J., Benefield, V., and Zhang, M. test five different types of DART-MS sample introduction techniques for a suite of explosives and reported that a Dart gas stream of 200 °C as well as the addition of an acetic acid dopant to wet swabs produced the best results as other methods even including thermal desorption “failed in one aspect or another to be high-throughput, sensitive, and/or robust” [ 465 ].…”

Rapid quantification of cannabidiol from oils by direct analysis in real time mass spectrometry

“…Since its first publication in 2005 by Cody et al , 12 the use of DART-MS has been demonstrated for rapid quality control of a wide variety of analytes, e.g. spices, 13,14 pesticides, 15 explosives 12,16 and polymers. 17 Rapid quantification methods using DART-MS have already been developed for nicotine in cigars 18 and melamine and cyanuric acid in milk powder.…”