Postvoid residual urine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: pooled analysis of eleven controlled studies with alfuzosin

McNeill, S. Alan; Hargreave, T. B.; Geffriaud-Ricouard, Christine; Santoni, Jean-Philippe; Roehrborn, Claus G.

doi:10.1016/s0090-4295(00)01021-9

Cited by 54 publications

(36 citation statements)

References 23 publications

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“…There may be many reasons for this. First, it is known that intra-and interindividual variability exists (24,39). Furthermore, as is the case for flow-rate testing, measurement of PVR does not distinguish obstruction from underactive bladder, nor does it correlate with urodynamic evidence of the severity or duration of obstruction (39).…”

Section: Measuring Pvrmentioning

confidence: 99%

“…First, it is known that intra-and interindividual variability exists (24,39). Furthermore, as is the case for flow-rate testing, measurement of PVR does not distinguish obstruction from underactive bladder, nor does it correlate with urodynamic evidence of the severity or duration of obstruction (39). Even though large PVR volume may indicate bladder dysfunction and herald progression of disease, clear-cut parameters for decision making, as yet, do not exist (26).…”

Section: Measuring Pvrmentioning

confidence: 99%

“…McNeill et al (39) examined the correlation between PVR and clinical efficacy of an alpha blocker. In 953 patients followed, only seven went into retention during the study, two in the medication group (0.3%) and five (1.3%) in the placebo group.…”

Section: Pvr £ 50 MLmentioning

confidence: 99%

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A practical guide to the evaluation and treatment of male lower urinary tract symptoms in the primary care setting

Rosenberg¹,

Staskin

Kaplan

et al. 2007

International Journal of Clinical Practice

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Summary Aims: Lower urinary tract symptoms (LUTS) are common in both men and women, and are among the most prevalent patient complaints heard by primary care physicians (PCPs). This article aims to provide PCPs with a logical algorithm for the assessment and initiation of treatment for LUTS in the male patient. Results: Management of LUTS involves a focused history and physical, as well as the assessment of bother. In patients for whom treatment is warranted, a series of decisions regarding therapy should be considered. Male patients commonly suffer from storage and/or voiding symptoms. Treatment of male LUTS is commonly begun with agents that are aimed at remedying the outlet symptoms of benign prostatic hyperplasia (BPH). When this intervention is ineffective or when refractory symptoms persist, consideration should be given to treating the storage symptoms characteristic of overactive bladder (OAB). Discussion: This article is intended to provide the PCP with a logical guide to the treatment of male LUTS. Benign prostatic hyperplasia and OAB predominate among the causes of these symptoms, and the PCP should be comfortable treating each. Recent data detailing the safety of the use of these treatments in the male patient are reviewed and incorporated into the algorithm. Conclusion: Primary care physicians are in a unique position to successfully identify and treat male patients with LUTS. With this paper, they now have a tool to approach treatment logically and practically.

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Section: Measuring Pvrmentioning

confidence: 99%

Section: Measuring Pvrmentioning

confidence: 99%

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A practical guide to the evaluation and treatment of male lower urinary tract symptoms in the primary care setting

Rosenberg¹,

Staskin

Kaplan

et al. 2007

International Journal of Clinical Practice

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“…A pooled analysis of 11 studies has recently been performed to determine the relationship between PVR and clinical parameters such as age, maximum flow rate, voided volume and PSA, as well as to characterise the effect of alfuzosin on PVR [13]. The studies involved a total of 953 patients with a PVR of 50–350 ml at baseline with follow-up data available up to 6 months.…”

Section: Impact Of Medical Treatmentmentioning

confidence: 99%

Long-Term Aspects of Medical Treatment of BPH

Schulman¹

2001

Eur Urol

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“…ALH is alphaadrenergic blockers [1] and relaxes the muscles in the prostate and bladder neck, making it easier to urinate. It is used to improve urination in men with benign prostatic hyperplasia [2].…”

Section: Introductionmentioning

confidence: 99%

Development and Validation of New RP-HPLC Method for the Estimation of Alfuzosin Hydrochloride in Bulk and Tablet Dosage Form

Patil¹,

Devdhe²,

Kale³

et al. 2013

AJAC

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A reverse phase high performance liquid chromatographic method (HPLC) has been developed for the estimation of Alfuzosin hydrochloride (ALH) in the pharmaceutical formulation using RP-C18 column. The mobile phase (Tetrahydrofuran, Acetonitrile and buffer (pH 3.50) was pumped at a flow rate of 1.5 ml/min in the ratio of 1:20:80 and the eluents were monitored at 254.0 nm. Linearity was obtained in the concentration range of 80 -120 µg/mL for ALH. The method was statistically validated and RSD was found to be less than 2% indicating high degree of accuracy and precision of the proposed HPLC method. Due to its simplicity, rapidness, high precision and accuracy, the proposed HPLC method may be used for determination of Alfuzosin hydrochloride in bulk drugs and in pharmaceutical dosage form.

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Postvoid residual urine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: pooled analysis of eleven controlled studies with alfuzosin

Cited by 54 publications

References 23 publications

A practical guide to the evaluation and treatment of male lower urinary tract symptoms in the primary care setting

A practical guide to the evaluation and treatment of male lower urinary tract symptoms in the primary care setting

Long-Term Aspects of Medical Treatment of BPH

Development and Validation of New RP-HPLC Method for the Estimation of Alfuzosin Hydrochloride in Bulk and Tablet Dosage Form

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